Study of the Protective Role of Ginseng Aqueous Extract on Lipid Profile (TC), (Tg), (HDL) and (LDL) in Male Rabbits Treated with Lead Acetate for 30 Days

• Main Authors: Hamzah, S. A. (Sarah), Jawad, R. A. (Rasha)
• Format: Article in Journal/Newspaper
• Language: Indonesian
• Published: ScienceScholar 2022
• Subjects: panax ginseng extract; lead acetate toxic; lipid profile; rabbit; Indonesia; Lepus arcticus
• Online Access: https://sciencescholar.us/publications/576360/study-of-the-protective-role-of-ginseng-aqueous-extract-on-lipid-profile-tc-tg-h

The Study involved twenty healthy adult white male rabbits (Lepus arcticus L.). the average weight (1500- 1600) Kg and aged from eight months to one year. The rabbits ware divided to four groups(G) each group contains five rabbits. G1 was treated with normal saline (1.5) ml orally as negative control group, G2 was treated with lead acetate (150) mg/kg as positive control group, G3 was treated with the aqueous extract of the Panax ginseng (400 ) mg/kg b.wt and G4 was treated with the aqueous extract of the Panax ginseng ( 400) mg/kg b.wt after 3 hours given them lead acetate (150 mg/kg b. wt/day) for peroid 30 days . study aimed to determine the protective role of Panax ginseng extract on Lipid profile like total cholesterol (TC) , triglycerides (Tg) , high-density lipoproteins (HDL) , low-density lipoproteins(LDL). The result of present study showed:- increase (P<0.05) in mean levels of high-density lipoproteins (HDL) in the (G3) and (G4) group compare with Second group (positive control G2). decrease (P<0.05) in mean levels total cholesterol (TC), triglycerides (Tg) low-density lipoproteins(LDL) in group (G3) and (G4) compare with Second group (positive control G2).