利用固定化金屬親和薄膜進行酵素固定化：右旋-乙內醯脲酶與脂肪分解酶

• Main Authors: 柯怡妙, Ko, Yi-Miao
• Other Authors: 化學工程學系所, 劉永銓, Yung-Chuan Liu
• Format: Other/Unknown Material
• Language: English
• Published: 化學工程學系所 2013
• Subjects: 右旋-乙內醯脲酶; D-Hydantoinase; 脂肪分解酶; 固定化金屬親和薄膜; 純化; 固定化; 金屬離子效應; 酵素穩定性; 親水性薄膜; 疏水性薄膜; Candida antartica lipase B; immobilized metal affinity mem-brane; purification; immobilization; metal ion effect; enzyme stability; hydrophilic membrane; hydrophobic membrane; Ida; Tive; Posi; Antarc*; Antarctica; antartic*
• Online Access: http://hdl.handle.net/11455/3192

右旋-乙內醯脲酶（D-Hydantoinase, DHTase）是一重要生化觸媒，能將D-5-substituted hydantoing水解成N-carbamoyl-D-p-hydroxyphenylglycine (Nca-HPG)，之後再利用N-carbamoyl-D-amino acid amidohydrolase (DCase)水解成D-p-Hydroxyphenylglycine (D-p-HGP)。D-p-HGP能與六青黴素酸（6-aminopenicillanic acid, 6-APA）反應生成合成Amoxicillin，Amoxicillin、Cefadroxil、Cef...