Komparativno ispitivanje mehanizama antiparazitskog i toksičnog dejstva gabaergičkih i holinergičkih antihelmintika

• Main Author: Ivanović, Saša
• Other Authors: Trailović, Saša, Jezdimirović, Milanka, Ćupić, Vitomir, Todorović, Zoran, Kulišić, Zoran
• Format: Doctoral or Postdoctoral Thesis
• Language: srp
• Published: Универзитет у Београду, Факултет ветеринарске медицине 2020
• Subjects: antiparazitici; mehanizam dejstva; toksičnost; GABA agonisti; holinergički agonisti; karvakrol; tribendimidin; antiparasitics; mechanism of action; toxicity; GABA agonists; cholinergic agonists; carvacrol; tribendimidine; Kanala; sami
• Online Access: https://nardus.mpn.gov.rs/handle/123456789/2976; http://eteze.bg.ac.rs/application/showtheses?thesesId=880; https://fedorabg.bg.ac.rs/fedora/get/o:7283/bdef:Content/download; http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=44858895; http://nardus.mpn.gov.rs/bitstream/id/20153/Disertacija.pdf; https://nardus.mpn.gov.rs/bitstream/id/20153/Disertacija.pdf; https://doi.org/10.2298/bg20131105ivanovic; https://hdl.handle.net/21.15107/rcub_nardus_2976

Gabaergički i holinergički sistem u neuro-mišićnom sistemu parazitskih nematoda su glavna ciljna mesta delovanja antihelmintika. U okviru holinergičkog sistema nematoda, farmakološki značaj ima pre svega nikotinski-acetilholinski receptor (nAChR). S druge strane, GABA-receptor parazitskih nematoda j...