血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性

Nagasaki University (長崎大学) 博士(医学) Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous pulmonary i...

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Main Author: 原田, 陽介
Format: Other/Unknown Material
Language:English
Published: American Society for Microbiology 2014
Subjects:
daptomycin
methicillin-resistant Staphylococcus aureus
hematogenous
pulmonary infection
taiga
Online Access:https://nagasaki-u.repo.nii.ac.jp/record/4302/files/ISYK688_Harada.pdf
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spelling ftnagasakiuniv:oai:nagasaki-u.repo.nii.ac.jp:00004302 2024-09-15T18:38:39+00:00 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性 In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection 原田, 陽介 2014-03-20 application/pdf https://nagasaki-u.repo.nii.ac.jp/record/4302/files/ISYK688_Harada.pdf eng eng American Society for Microbiology 10.1128/AAC.02331-12 http://hdl.handle.net/10069/34637 Antimicrobial Agents and Chemotherapy 6 57 2841 2844 甲医歯薬第688号 00664804 10986596 https://nagasaki-u.repo.nii.ac.jp/record/4302/files/ISYK688_Harada.pdf c 2013, American Society for Microbiology. open access daptomycin methicillin-resistant Staphylococcus aureus hematogenous pulmonary infection VoR 2014 ftnagasakiuniv 2024-08-23T06:19:41Z Nagasaki University (長崎大学) 博士(医学) Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous pulmonary infection mouse model. Compared with control results, daptomycin improved survival (P<0.001) and decreased the number of abscesses and bacteria in the lungs (P<0.01). Daptomycin may be an effective therapeutic option for MRSA hematogenous pulmonary infection. 長崎大学学位論文 学位記番号:博(医歯薬)甲第688号 学位授与年月日:平成26年3月20日 Author: Harada Yosuke, Yanagihara Katsunori, Yamada Koichi, Migiyama Yohei, Nagaoka Kentaro, Morinaga Yoshitomo, Nakamura Shigeki, Imamura Yoshifumi, Hasegawa Hiroo, Miyazaki Taiga, Izumikawa Koichi, Kakeya Hiroshi, Kohno Shigeru Citation: Antimicrobial Agents and Chemotherapy, 57(6), pp.2841-2844; 2013 Nagasaki University (長崎大学), 博士(医学) (2014-03-20) doctoral thesis Other/Unknown Material taiga NAOSITE: Nagasaki University Academic Output SITE
institution Open Polar
collection NAOSITE: Nagasaki University Academic Output SITE
op_collection_id ftnagasakiuniv
language English
topic daptomycin
methicillin-resistant Staphylococcus aureus
hematogenous
pulmonary infection
spellingShingle daptomycin
methicillin-resistant Staphylococcus aureus
hematogenous
pulmonary infection
原田, 陽介
血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性
topic_facet daptomycin
methicillin-resistant Staphylococcus aureus
hematogenous
pulmonary infection
description Nagasaki University (長崎大学) 博士(医学) Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous pulmonary infection mouse model. Compared with control results, daptomycin improved survival (P<0.001) and decreased the number of abscesses and bacteria in the lungs (P<0.01). Daptomycin may be an effective therapeutic option for MRSA hematogenous pulmonary infection. 長崎大学学位論文 学位記番号:博(医歯薬)甲第688号 学位授与年月日:平成26年3月20日 Author: Harada Yosuke, Yanagihara Katsunori, Yamada Koichi, Migiyama Yohei, Nagaoka Kentaro, Morinaga Yoshitomo, Nakamura Shigeki, Imamura Yoshifumi, Hasegawa Hiroo, Miyazaki Taiga, Izumikawa Koichi, Kakeya Hiroshi, Kohno Shigeru Citation: Antimicrobial Agents and Chemotherapy, 57(6), pp.2841-2844; 2013 Nagasaki University (長崎大学), 博士(医学) (2014-03-20) doctoral thesis
format Other/Unknown Material
author 原田, 陽介
author_facet 原田, 陽介
author_sort 原田, 陽介
title 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性
title_short 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性
title_full 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性
title_fullStr 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性
title_full_unstemmed 血行性MRSA肺感染マウスモデルにおけるダプトマイシンの有効性
title_sort 血行性mrsa肺感染マウスモデルにおけるダプトマイシンの有効性
publisher American Society for Microbiology
publishDate 2014
url https://nagasaki-u.repo.nii.ac.jp/record/4302/files/ISYK688_Harada.pdf
genre taiga
genre_facet taiga
op_relation 10.1128/AAC.02331-12
http://hdl.handle.net/10069/34637
Antimicrobial Agents and Chemotherapy
6
57
2841
2844
甲医歯薬第688号
00664804
10986596
https://nagasaki-u.repo.nii.ac.jp/record/4302/files/ISYK688_Harada.pdf
op_rights c 2013, American Society for Microbiology.
open access
_version_ 1810483063249960960

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