Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome
Background: Most medical treatments for carpal tunnel syndrome (CTS) have focused on suppressing the inflammatory process. Injection of dexamethasone acetate might provide the necessary cellular and humoral mediators to induce a healing cascade. Dexamethasone is a water-soluble steroid that is safe...
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ftmui:oai:ojs.journals.mui.ac.ir:article/6600 2023-05-15T16:02:05+02:00 Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome Ali Reza Moghtaderi Neda Moghtaderi Amir Loghmani 2011-05-16 application/octetstream text/xml http://journals.mui.ac.ir/jrms/article/view/6600 en eng Journal of Research in Medical Sciences مجله پژوهش در علوم پزشکی http://journals.mui.ac.ir/jrms/article/download/6600/27753 Journal of Research in Medical Sciences (JRMS) applies the Creative Commons Attribution License (CCAL) to all of its published papers. Under the CCAL, authors retain ownership of the copyright for their article, but authors allow anyone to download, reuse, reprint, modify, distribute, and/or copy articles in JRMS, so long as the original authors and source are cited. No permission is required from the authors or the publishers. [ License summary ] [ License full text ] CC-BY Journal of Research in Medical Sciences; Vol 16, No 5 (2011) مجله پژوهش در علوم پزشکی; Vol 16, No 5 (2011) Physical Medicin & Rehabilitation Dexamethasone acetate injection CTS pain intensity electro physiologic parameters. 2011 ftmui 2013-11-05T19:44:56Z Background: Most medical treatments for carpal tunnel syndrome (CTS) have focused on suppressing the inflammatory process. Injection of dexamethasone acetate might provide the necessary cellular and humoral mediators to induce a healing cascade. Dexamethasone is a water-soluble steroid that is safe to be used in the third trimester, especially as a local treatment. The aim of this study was to evaluate the effectiveness of 4 mg dexamethasone acetate injection for treatment of carpal tunnel syndrome in pregnancy period. Methods: Twenty pregnant patients with carpal tunnel syndrome were recruited using strict inclusion and exclusion criteria. All patients were injected with 4 mg of Dexamethasone acetate and 0.5 ml lidocaeine 1% under the carpal tunnel. Pain intensity [based on visual analog scale (VAS)] and electrophysiologic parameters of median nerve (transcarpal median sensory nerve conduction velocity (SNCV), distal motor latency (DML), and distal sensory latency (DSL) were recorded before and 3 weeks after injection.Results: The average pain scores before and 3 weeks after Dexamethasone acetate injection was 8.70 ± 0.92 and 4.30 ± 0.76 respectively (p < 0.005). Also transcarpal sensory nerve conduction velocity of median nerve was 33.7 ± 6.3 m/s and 24.5 ± 6.8 m/s (p = 0.001); distal motor latency of median nerve was 5.16 ± 1.04 ms and 4.70 ± 0.53 ms (p = 0.001) and distal sensory latency of median nerve was 4.84 ± 0.77 ms and 4.2 ± 0.6 ms (p = 0.001), respectively.Conclusions: After Dexamethasone acetate injection, pain intensity and electerophysiologic parameters were significantly improved. This study offers encouraging results for an alternative minimally invasive treatment for CTS in pregnant women.Keywords: Dexamethasone Acetate Injection, Carpal Tunnel Syndrome, Pain Intensity, Electrophysiologic Parameters. Other/Unknown Material DML Isfahan University of Medical Sciences: MUI Periodicals |
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Isfahan University of Medical Sciences: MUI Periodicals |
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English |
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Physical Medicin & Rehabilitation Dexamethasone acetate injection CTS pain intensity electro physiologic parameters. |
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Physical Medicin & Rehabilitation Dexamethasone acetate injection CTS pain intensity electro physiologic parameters. Ali Reza Moghtaderi Neda Moghtaderi Amir Loghmani Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome |
topic_facet |
Physical Medicin & Rehabilitation Dexamethasone acetate injection CTS pain intensity electro physiologic parameters. |
description |
Background: Most medical treatments for carpal tunnel syndrome (CTS) have focused on suppressing the inflammatory process. Injection of dexamethasone acetate might provide the necessary cellular and humoral mediators to induce a healing cascade. Dexamethasone is a water-soluble steroid that is safe to be used in the third trimester, especially as a local treatment. The aim of this study was to evaluate the effectiveness of 4 mg dexamethasone acetate injection for treatment of carpal tunnel syndrome in pregnancy period. Methods: Twenty pregnant patients with carpal tunnel syndrome were recruited using strict inclusion and exclusion criteria. All patients were injected with 4 mg of Dexamethasone acetate and 0.5 ml lidocaeine 1% under the carpal tunnel. Pain intensity [based on visual analog scale (VAS)] and electrophysiologic parameters of median nerve (transcarpal median sensory nerve conduction velocity (SNCV), distal motor latency (DML), and distal sensory latency (DSL) were recorded before and 3 weeks after injection.Results: The average pain scores before and 3 weeks after Dexamethasone acetate injection was 8.70 ± 0.92 and 4.30 ± 0.76 respectively (p < 0.005). Also transcarpal sensory nerve conduction velocity of median nerve was 33.7 ± 6.3 m/s and 24.5 ± 6.8 m/s (p = 0.001); distal motor latency of median nerve was 5.16 ± 1.04 ms and 4.70 ± 0.53 ms (p = 0.001) and distal sensory latency of median nerve was 4.84 ± 0.77 ms and 4.2 ± 0.6 ms (p = 0.001), respectively.Conclusions: After Dexamethasone acetate injection, pain intensity and electerophysiologic parameters were significantly improved. This study offers encouraging results for an alternative minimally invasive treatment for CTS in pregnant women.Keywords: Dexamethasone Acetate Injection, Carpal Tunnel Syndrome, Pain Intensity, Electrophysiologic Parameters. |
author |
Ali Reza Moghtaderi Neda Moghtaderi Amir Loghmani |
author_facet |
Ali Reza Moghtaderi Neda Moghtaderi Amir Loghmani |
author_sort |
Ali Reza Moghtaderi |
title |
Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome |
title_short |
Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome |
title_full |
Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome |
title_fullStr |
Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome |
title_full_unstemmed |
Evaluation of the effectiveness of local Dexamethasone injection in pregnant women with carpal tunnel syndrome |
title_sort |
evaluation of the effectiveness of local dexamethasone injection in pregnant women with carpal tunnel syndrome |
publisher |
Journal of Research in Medical Sciences |
publishDate |
2011 |
url |
http://journals.mui.ac.ir/jrms/article/view/6600 |
genre |
DML |
genre_facet |
DML |
op_source |
Journal of Research in Medical Sciences; Vol 16, No 5 (2011) مجله پژوهش در علوم پزشکی; Vol 16, No 5 (2011) |
op_relation |
http://journals.mui.ac.ir/jrms/article/download/6600/27753 |
op_rights |
Journal of Research in Medical Sciences (JRMS) applies the Creative Commons Attribution License (CCAL) to all of its published papers. Under the CCAL, authors retain ownership of the copyright for their article, but authors allow anyone to download, reuse, reprint, modify, distribute, and/or copy articles in JRMS, so long as the original authors and source are cited. No permission is required from the authors or the publishers. [ License summary ] [ License full text ] |
op_rightsnorm |
CC-BY |
_version_ |
1766397701617876992 |