Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species
The effects of crude oil (Szeged-Algyő, Hungary) and oil fractions (F1: rich in aromatics; F2 fraction: free from aromatics) were investigated on liver CYP1A isoenzymes and antioxidant defence system following their i.p. injection into different freshwater fish species: carp ( Cyprinus carpio L.), s...
Published in: | Acta Biologica Hungarica |
---|---|
Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | Hungarian |
Published: |
Akadémiai Kiadó
2010
|
Subjects: | |
Online Access: | http://real.mtak.hu/70387/ http://real.mtak.hu/70387/1/abiol.61.2010.3.3.pdf https://doi.org/10.1556/ABiol.61.2010.3.3 |
id |
ftmtak:oai:real.mtak.hu:70387 |
---|---|
record_format |
openpolar |
spelling |
ftmtak:oai:real.mtak.hu:70387 2023-05-15T16:08:39+02:00 Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species Deér, Aranka Henczová, Mária Banka, L. Varanka, Zs. Nemcsók, J. 2010 text http://real.mtak.hu/70387/ http://real.mtak.hu/70387/1/abiol.61.2010.3.3.pdf https://doi.org/10.1556/ABiol.61.2010.3.3 hu hun Akadémiai Kiadó http://real.mtak.hu/70387/1/abiol.61.2010.3.3.pdf Deér, Aranka and Henczová, Mária and Banka, L. and Varanka, Zs. and Nemcsók, J. (2010) Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species. Acta Biologica Hungarica, 61 (3). pp. 262-273. ISSN 0236-5383 QH Natural history / természetrajz Article PeerReviewed 2010 ftmtak https://doi.org/10.1556/ABiol.61.2010.3.3 2017-11-29T23:58:33Z The effects of crude oil (Szeged-Algyő, Hungary) and oil fractions (F1: rich in aromatics; F2 fraction: free from aromatics) were investigated on liver CYP1A isoenzymes and antioxidant defence system following their i.p. injection into different freshwater fish species: carp ( Cyprinus carpio L.), silver carp ( Hyphothalmichtys molitrix V.), and European eel ( Anquilla anquilla ). A dose of 2 mL kg −1 crude oil enhanced EROD activity 8-fold in carp and only 5-fold in eel after 3 days. Oil fraction F1 caused only a 2-fold induction in EROD activity only in carp, while F2 fraction caused significant inhibition in all three investigated fish species. The antioxidant parameters [lipid peroxidation (LP), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione (GSH)] were measured following the treatment. A decrease of 50% in CAT activity was observed after oil treatment. The GSH level enhanced, resulting the protective effects against LP. The same dose of crude oil but a longer duration time resulted in lower CYP1A induction in carp and antioxidant parameters had returned close to control. In all treatments the EROD isoenzymes proved to be more sensitive and the effects of oil treatment showed species to be different. Carp proved to be more sensitive than eel or silver carp. Article in Journal/Newspaper European eel MTAK: REAL (Library and Information Centre of the Hungarian Academy of Sciences Acta Biologica Hungarica 61 3 262 273 |
institution |
Open Polar |
collection |
MTAK: REAL (Library and Information Centre of the Hungarian Academy of Sciences |
op_collection_id |
ftmtak |
language |
Hungarian |
topic |
QH Natural history / természetrajz |
spellingShingle |
QH Natural history / természetrajz Deér, Aranka Henczová, Mária Banka, L. Varanka, Zs. Nemcsók, J. Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
topic_facet |
QH Natural history / természetrajz |
description |
The effects of crude oil (Szeged-Algyő, Hungary) and oil fractions (F1: rich in aromatics; F2 fraction: free from aromatics) were investigated on liver CYP1A isoenzymes and antioxidant defence system following their i.p. injection into different freshwater fish species: carp ( Cyprinus carpio L.), silver carp ( Hyphothalmichtys molitrix V.), and European eel ( Anquilla anquilla ). A dose of 2 mL kg −1 crude oil enhanced EROD activity 8-fold in carp and only 5-fold in eel after 3 days. Oil fraction F1 caused only a 2-fold induction in EROD activity only in carp, while F2 fraction caused significant inhibition in all three investigated fish species. The antioxidant parameters [lipid peroxidation (LP), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione (GSH)] were measured following the treatment. A decrease of 50% in CAT activity was observed after oil treatment. The GSH level enhanced, resulting the protective effects against LP. The same dose of crude oil but a longer duration time resulted in lower CYP1A induction in carp and antioxidant parameters had returned close to control. In all treatments the EROD isoenzymes proved to be more sensitive and the effects of oil treatment showed species to be different. Carp proved to be more sensitive than eel or silver carp. |
format |
Article in Journal/Newspaper |
author |
Deér, Aranka Henczová, Mária Banka, L. Varanka, Zs. Nemcsók, J. |
author_facet |
Deér, Aranka Henczová, Mária Banka, L. Varanka, Zs. Nemcsók, J. |
author_sort |
Deér, Aranka |
title |
Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
title_short |
Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
title_full |
Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
title_fullStr |
Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
title_full_unstemmed |
Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
title_sort |
effects of crude oil and oil fractions on the liver p450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species |
publisher |
Akadémiai Kiadó |
publishDate |
2010 |
url |
http://real.mtak.hu/70387/ http://real.mtak.hu/70387/1/abiol.61.2010.3.3.pdf https://doi.org/10.1556/ABiol.61.2010.3.3 |
genre |
European eel |
genre_facet |
European eel |
op_relation |
http://real.mtak.hu/70387/1/abiol.61.2010.3.3.pdf Deér, Aranka and Henczová, Mária and Banka, L. and Varanka, Zs. and Nemcsók, J. (2010) Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species. Acta Biologica Hungarica, 61 (3). pp. 262-273. ISSN 0236-5383 |
op_doi |
https://doi.org/10.1556/ABiol.61.2010.3.3 |
container_title |
Acta Biologica Hungarica |
container_volume |
61 |
container_issue |
3 |
container_start_page |
262 |
op_container_end_page |
273 |
_version_ |
1766404675839459328 |