Analyzing longitudinally correlated failure time data - a generalized estimating equation approach
Thesis (M.Sc.)--Memorial University of Newfoundland, 2001. Mathematics and Statistics Bibliography: leaves 87-89. Multivariate correlated failure time data can be classified into two different groups: structural failure time data and longitudinal failure time data. As compared to the analysis of the...
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ftmemorialunivdc:oai:collections.mun.ca:theses4/14866 2023-05-15T17:23:33+02:00 Analyzing longitudinally correlated failure time data - a generalized estimating equation approach Hasan, Md. Tariqul, 1972- Memorial University of Newfoundland. Dept. of Mathematics and Statistics 2001 ix, 89 leaves. Image/jpeg; Application/pdf http://collections.mun.ca/cdm/ref/collection/theses4/id/14866 Eng eng Electronic Theses and Dissertations (10.27 MB) -- http://collections.mun.ca/PDFs/theses/Hasan_MDTariqul.pdf a1538826 http://collections.mun.ca/cdm/ref/collection/theses4/id/14866 The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission. Paper copy kept in the Centre for Newfoundland Studies, Memorial University Libraries Failure time data analysis Text Electronic thesis or dissertation 2001 ftmemorialunivdc 2015-08-06T19:21:05Z Thesis (M.Sc.)--Memorial University of Newfoundland, 2001. Mathematics and Statistics Bibliography: leaves 87-89. Multivariate correlated failure time data can be classified into two different groups: structural failure time data and longitudinal failure time data. As compared to the analysis of the structural failure time data, the analysis of longitudinal failure time data has however proven to be difficult, perhaps because of the difficulty in the modeling the true longitudinal correlation structures. In the present thesis, following certain longitudinal correlation models, recently developed for discrete data, we develop three longitudinal correlation models for exponential failure times to deal with such multivariate longitudinal data. Under these three models, we construct the co-variance structures of the martingales of the failure times for both uncensored and censored cases, and use them to develop a generalized estimating equation approach to estimate the parameters of main interest, namely, the hazard ratio parameters. The efficiency loss due to misspecification of the correlation structure is studied for both uncensored and censored cases. As the proposed generalized estimating equation approach use either the underlying true correlation structure for both uncensored and censored cases or a suitable robust correlation structure for the uncensored case, the methodology yields consistent as well as efficient estimators for the hazard ratio parameters. We apply the methodology to a numerical example. Thesis Newfoundland studies University of Newfoundland Memorial University of Newfoundland: Digital Archives Initiative (DAI) |
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Memorial University of Newfoundland: Digital Archives Initiative (DAI) |
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English |
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Failure time data analysis |
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Failure time data analysis Hasan, Md. Tariqul, 1972- Analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
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Failure time data analysis |
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Thesis (M.Sc.)--Memorial University of Newfoundland, 2001. Mathematics and Statistics Bibliography: leaves 87-89. Multivariate correlated failure time data can be classified into two different groups: structural failure time data and longitudinal failure time data. As compared to the analysis of the structural failure time data, the analysis of longitudinal failure time data has however proven to be difficult, perhaps because of the difficulty in the modeling the true longitudinal correlation structures. In the present thesis, following certain longitudinal correlation models, recently developed for discrete data, we develop three longitudinal correlation models for exponential failure times to deal with such multivariate longitudinal data. Under these three models, we construct the co-variance structures of the martingales of the failure times for both uncensored and censored cases, and use them to develop a generalized estimating equation approach to estimate the parameters of main interest, namely, the hazard ratio parameters. The efficiency loss due to misspecification of the correlation structure is studied for both uncensored and censored cases. As the proposed generalized estimating equation approach use either the underlying true correlation structure for both uncensored and censored cases or a suitable robust correlation structure for the uncensored case, the methodology yields consistent as well as efficient estimators for the hazard ratio parameters. We apply the methodology to a numerical example. |
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Memorial University of Newfoundland. Dept. of Mathematics and Statistics |
format |
Thesis |
author |
Hasan, Md. Tariqul, 1972- |
author_facet |
Hasan, Md. Tariqul, 1972- |
author_sort |
Hasan, Md. Tariqul, 1972- |
title |
Analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
title_short |
Analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
title_full |
Analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
title_fullStr |
Analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
title_full_unstemmed |
Analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
title_sort |
analyzing longitudinally correlated failure time data - a generalized estimating equation approach |
publishDate |
2001 |
url |
http://collections.mun.ca/cdm/ref/collection/theses4/id/14866 |
genre |
Newfoundland studies University of Newfoundland |
genre_facet |
Newfoundland studies University of Newfoundland |
op_source |
Paper copy kept in the Centre for Newfoundland Studies, Memorial University Libraries |
op_relation |
Electronic Theses and Dissertations (10.27 MB) -- http://collections.mun.ca/PDFs/theses/Hasan_MDTariqul.pdf a1538826 http://collections.mun.ca/cdm/ref/collection/theses4/id/14866 |
op_rights |
The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission. |
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1766113216417497088 |