The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax)
Thesis (M.Sc.)--Memorial University of Newfoundland, 2002. Biology Includes bibliographical references Trimethylamine oxide (TMAO) is common to most marine fishes; however, the role TMAO plays in the physiology of marine fish is not well understood. I have used two distinct TMAO accumulating fish ...
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ftmemorialunivdc:oai:collections.mun.ca:theses3/160957 2023-05-15T17:23:32+02:00 The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) Treberg, Jason R., 1976- Memorial University of Newfoundland. Dept. of Biology 2002 xi, 73 leaves Image/jpeg; Application/pdf http://collections.mun.ca/cdm/ref/collection/theses3/id/160957 eng eng Electronic Theses and Dissertations (8.92 MB) -- http://collections.mun.ca/PDFs/theses/Treberg_JasonR.pdf a1591354 http://collections.mun.ca/cdm/ref/collection/theses3/id/160957 The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission. Paper copy kept in the Centre for Newfoundland Studies, Memorial University Libraries Deep-sea fishes--Metabolism Deep-sea fishes--Physiology Rainbow smelt--Metabolism Rainbow smelt--Physiology Text Electronic thesis or dissertation 2002 ftmemorialunivdc 2015-08-06T19:20:24Z Thesis (M.Sc.)--Memorial University of Newfoundland, 2002. Biology Includes bibliographical references Trimethylamine oxide (TMAO) is common to most marine fishes; however, the role TMAO plays in the physiology of marine fish is not well understood. I have used two distinct TMAO accumulating fish 'types', deep-sea fish and smelt (Osmerus mordax), to compare differences in the levels, intertissue distribution and capacity for synthesis of TMAO in fish with high and low levels of TMAO. Several consistencies were found. The intertissue distribution of TMAO showed a trend of locomotory muscle > heart > liver= kidney = brain. Levels of trimethylamine oxidase, the enzyme required for TMAO synthesis, did not correlate with higher tissue TMAO content indicating that enhanced endogenous synthetic capacity is not responsible for elevated TMAO content. Finally, evidence for the active uptake of TMAO into striated muscle and the regulation of TMAO concentration in white muscle is presented, possibly due to some role TMAO plays in muscle function. Thesis Newfoundland studies University of Newfoundland Memorial University of Newfoundland: Digital Archives Initiative (DAI) |
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Memorial University of Newfoundland: Digital Archives Initiative (DAI) |
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ftmemorialunivdc |
language |
English |
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Deep-sea fishes--Metabolism Deep-sea fishes--Physiology Rainbow smelt--Metabolism Rainbow smelt--Physiology |
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Deep-sea fishes--Metabolism Deep-sea fishes--Physiology Rainbow smelt--Metabolism Rainbow smelt--Physiology Treberg, Jason R., 1976- The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) |
topic_facet |
Deep-sea fishes--Metabolism Deep-sea fishes--Physiology Rainbow smelt--Metabolism Rainbow smelt--Physiology |
description |
Thesis (M.Sc.)--Memorial University of Newfoundland, 2002. Biology Includes bibliographical references Trimethylamine oxide (TMAO) is common to most marine fishes; however, the role TMAO plays in the physiology of marine fish is not well understood. I have used two distinct TMAO accumulating fish 'types', deep-sea fish and smelt (Osmerus mordax), to compare differences in the levels, intertissue distribution and capacity for synthesis of TMAO in fish with high and low levels of TMAO. Several consistencies were found. The intertissue distribution of TMAO showed a trend of locomotory muscle > heart > liver= kidney = brain. Levels of trimethylamine oxidase, the enzyme required for TMAO synthesis, did not correlate with higher tissue TMAO content indicating that enhanced endogenous synthetic capacity is not responsible for elevated TMAO content. Finally, evidence for the active uptake of TMAO into striated muscle and the regulation of TMAO concentration in white muscle is presented, possibly due to some role TMAO plays in muscle function. |
author2 |
Memorial University of Newfoundland. Dept. of Biology |
format |
Thesis |
author |
Treberg, Jason R., 1976- |
author_facet |
Treberg, Jason R., 1976- |
author_sort |
Treberg, Jason R., 1976- |
title |
The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) |
title_short |
The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) |
title_full |
The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) |
title_fullStr |
The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) |
title_full_unstemmed |
The accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (Osmerus mordax) |
title_sort |
accumulation, synthetic capacity and intertissue distribution of trimethylamine oxide in deep-sea fish and the cold adapted smelt (osmerus mordax) |
publishDate |
2002 |
url |
http://collections.mun.ca/cdm/ref/collection/theses3/id/160957 |
genre |
Newfoundland studies University of Newfoundland |
genre_facet |
Newfoundland studies University of Newfoundland |
op_source |
Paper copy kept in the Centre for Newfoundland Studies, Memorial University Libraries |
op_relation |
Electronic Theses and Dissertations (8.92 MB) -- http://collections.mun.ca/PDFs/theses/Treberg_JasonR.pdf a1591354 http://collections.mun.ca/cdm/ref/collection/theses3/id/160957 |
op_rights |
The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission. |
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