Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua)
Currently, little information exists on how chronic hypoxia influences fish physiology. Thus, a comprehensive examination of how this ecologically-relevant environmental challenge affects the cardiorespiratory physiology, exercise performance and hypoxia tolerance of Atlantic cod (Gadus morhud) was...
Main Author: | |
---|---|
Format: | Thesis |
Language: | English |
Published: |
Memorial University of Newfoundland
2010
|
Subjects: | |
Online Access: | https://research.library.mun.ca/9146/ https://research.library.mun.ca/9146/1/Petersen_Lene.pdf |
id |
ftmemorialuniv:oai:research.library.mun.ca:9146 |
---|---|
record_format |
openpolar |
spelling |
ftmemorialuniv:oai:research.library.mun.ca:9146 2023-10-01T03:54:32+02:00 Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) Petersen, Lene Hebsgaard 2010 application/pdf https://research.library.mun.ca/9146/ https://research.library.mun.ca/9146/1/Petersen_Lene.pdf en eng Memorial University of Newfoundland https://research.library.mun.ca/9146/1/Petersen_Lene.pdf Petersen, Lene Hebsgaard <https://research.library.mun.ca/view/creator_az/Petersen=3ALene_Hebsgaard=3A=3A.html> (2010) Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua). Doctoral (PhD) thesis, Memorial University of Newfoundland. thesis_license Thesis NonPeerReviewed 2010 ftmemorialuniv 2023-09-03T06:47:15Z Currently, little information exists on how chronic hypoxia influences fish physiology. Thus, a comprehensive examination of how this ecologically-relevant environmental challenge affects the cardiorespiratory physiology, exercise performance and hypoxia tolerance of Atlantic cod (Gadus morhud) was performed. -- Exposure to acute hypoxia (PwO₂ 8-9 kPa) lowered the Ucrit of normoxic-acclimated cod by approx. 30%, and this was associated with large decreases in max. oxygen consumption (MO₂), metabolic scope (≥ 50%), and maximum heart rate (ƒH) and cardiac output (Q) (by 16 and 22%). Hypoxic acclimation (6-12 weeks at 10 °C; PwO₂ 8-9 kPa) elevated normoxic MO₂ (standard by 27 %; routine by 44%) compared with normoxic controls, but did not influence Ucrit, max. MO₂ or metabolic scope under either normoxia or hypoxia. Further, although, resting and maximum values for Q were significantly diminished in hypoxic-acclimated cod due to lower values for stroke volume (Sᵥ), increased ƒH partially compensated for the latter, and hypoxic-acclimated cod were able to consume more oxygen for a given cardiac output. -- This lower in vivo cardiac pumping capacity proved not to be a regulated decrease as hypoxic acclimation reduced in situ values for maximum Sᵥ, the scope for Sᵥ, and consequently maximum cardiac output (Qmax) (by 19%). However, hypoxic-acclimated fish were able to sustain Q better under hypoxia, and the recovery of Qmax (compared to initial Qmax) was significantly improved (94 vs. 83%) as compared with normoxic controls. -- Although several physiological adjustments had taken place during the 6-12 weeks of hypoxic acclimation [increased ƒH; elevated hematocrit (Hct) by 11 % and [Hb] by 14 %; enhanced tissue oxygen extraction efficiency by ~ 15%; and a more robust stress response (2-8 fold higher levels of plasma catecholamines at PwO₂'s of 5.3 and 2.7 kPa)], these adjustments were only successful in improving the cod's critical oxygen tension (Pcrit of normoxic and hypoxic-acclimated cod 8.1 ± 0.5 vs. 6.6 ± 0.6 ... Thesis atlantic cod Gadus morhua Memorial University of Newfoundland: Research Repository |
institution |
Open Polar |
collection |
Memorial University of Newfoundland: Research Repository |
op_collection_id |
ftmemorialuniv |
language |
English |
description |
Currently, little information exists on how chronic hypoxia influences fish physiology. Thus, a comprehensive examination of how this ecologically-relevant environmental challenge affects the cardiorespiratory physiology, exercise performance and hypoxia tolerance of Atlantic cod (Gadus morhud) was performed. -- Exposure to acute hypoxia (PwO₂ 8-9 kPa) lowered the Ucrit of normoxic-acclimated cod by approx. 30%, and this was associated with large decreases in max. oxygen consumption (MO₂), metabolic scope (≥ 50%), and maximum heart rate (ƒH) and cardiac output (Q) (by 16 and 22%). Hypoxic acclimation (6-12 weeks at 10 °C; PwO₂ 8-9 kPa) elevated normoxic MO₂ (standard by 27 %; routine by 44%) compared with normoxic controls, but did not influence Ucrit, max. MO₂ or metabolic scope under either normoxia or hypoxia. Further, although, resting and maximum values for Q were significantly diminished in hypoxic-acclimated cod due to lower values for stroke volume (Sᵥ), increased ƒH partially compensated for the latter, and hypoxic-acclimated cod were able to consume more oxygen for a given cardiac output. -- This lower in vivo cardiac pumping capacity proved not to be a regulated decrease as hypoxic acclimation reduced in situ values for maximum Sᵥ, the scope for Sᵥ, and consequently maximum cardiac output (Qmax) (by 19%). However, hypoxic-acclimated fish were able to sustain Q better under hypoxia, and the recovery of Qmax (compared to initial Qmax) was significantly improved (94 vs. 83%) as compared with normoxic controls. -- Although several physiological adjustments had taken place during the 6-12 weeks of hypoxic acclimation [increased ƒH; elevated hematocrit (Hct) by 11 % and [Hb] by 14 %; enhanced tissue oxygen extraction efficiency by ~ 15%; and a more robust stress response (2-8 fold higher levels of plasma catecholamines at PwO₂'s of 5.3 and 2.7 kPa)], these adjustments were only successful in improving the cod's critical oxygen tension (Pcrit of normoxic and hypoxic-acclimated cod 8.1 ± 0.5 vs. 6.6 ± 0.6 ... |
format |
Thesis |
author |
Petersen, Lene Hebsgaard |
spellingShingle |
Petersen, Lene Hebsgaard Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) |
author_facet |
Petersen, Lene Hebsgaard |
author_sort |
Petersen, Lene Hebsgaard |
title |
Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) |
title_short |
Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) |
title_full |
Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) |
title_fullStr |
Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) |
title_full_unstemmed |
Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua) |
title_sort |
effects of chronic hypoxia on the cardiorespiratory physiology of atlantic cod (gadus morhua) |
publisher |
Memorial University of Newfoundland |
publishDate |
2010 |
url |
https://research.library.mun.ca/9146/ https://research.library.mun.ca/9146/1/Petersen_Lene.pdf |
genre |
atlantic cod Gadus morhua |
genre_facet |
atlantic cod Gadus morhua |
op_relation |
https://research.library.mun.ca/9146/1/Petersen_Lene.pdf Petersen, Lene Hebsgaard <https://research.library.mun.ca/view/creator_az/Petersen=3ALene_Hebsgaard=3A=3A.html> (2010) Effects of chronic hypoxia on the cardiorespiratory physiology of Atlantic cod (Gadus morhua). Doctoral (PhD) thesis, Memorial University of Newfoundland. |
op_rights |
thesis_license |
_version_ |
1778522296121556992 |