A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland
Endocrine disrupting chemicals (EDCs), found in the environment, can cause hypothyroidism, infertility, and neurodevelopmental deficits. EDCs can be transported long distances on water currents and can bioaccumulate in marine food webs. Two water currents around Newfoundland are suspected of transpo...
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ftmemorialuniv:oai:research.library.mun.ca:14789 2023-10-01T03:56:05+02:00 A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland Babichuk, Nicole Allen 2021-05 application/pdf https://research.library.mun.ca/14789/ https://research.library.mun.ca/14789/1/thesis.pdf en eng Memorial University of Newfoundland https://research.library.mun.ca/14789/1/thesis.pdf Babichuk, Nicole Allen <https://research.library.mun.ca/view/creator_az/Babichuk=3ANicole_Allen=3A=3A.html> (2021) A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland. Doctoral (PhD) thesis, Memorial University of Newfoundland. thesis_license Thesis NonPeerReviewed 2021 ftmemorialuniv 2023-09-03T06:49:57Z Endocrine disrupting chemicals (EDCs), found in the environment, can cause hypothyroidism, infertility, and neurodevelopmental deficits. EDCs can be transported long distances on water currents and can bioaccumulate in marine food webs. Two water currents around Newfoundland are suspected of transporting EDCs to adjacent marine ecosystems. Newfoundlanders may be exposed to EDCs through consumption of local seafood contaminated with EDCs. This study investigated EDC exposure in rural Newfoundland population by 1) testing local seafood species for the presence of EDCs, 2) determining the extent of local seafood consumption by surveying residents of two rural communities (Burin and New-Wes-Valley), 3) measuring serum thyroid hormones and plasma EDC concentrations in individuals who participated in the seafood consumption survey, and 4) exploring associations between seafood consumption, EDCs and thyroid hormones in participants. Liver samples from cod (Gadus morhua) and turbot (Scophthalmus maximus) showed the presence of polybrominated diphenyl ethers (PBDEs), which were commonly used as flame retardants. There were higher levels of PBDEs in fish samples from the west coast compared to those from the northeast coast of Newfoundland. Residents from the study communities consumed local cod more than any other species, and seafood consumption was higher in males than in females; and higher in older (> 50 years) than in younger (<50 years) participants. Increasing frequency of local cod consumption was positively associated with increasing PCB (-105, -118, -138, -170, -180 and ΣPCBs) and p,p’-DDE concentrations in participants. Therefore local cod consumption may be a source of exposure to these EDCs for rural Newfoundlanders. All participants had at least 11 EDCs present in their plasma; polychlorinated biphenyl (PCB), polybrominated biphenyl (PBB) and dichlorodiphenyldichloroethylene (p,p’-DDE) concentrations were higher in older participants, reflecting exposure to EDCs that have since been discontinued; ... Thesis Gadus morhua Newfoundland Scophthalmus maximus Turbot Memorial University of Newfoundland: Research Repository |
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Memorial University of Newfoundland: Research Repository |
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Endocrine disrupting chemicals (EDCs), found in the environment, can cause hypothyroidism, infertility, and neurodevelopmental deficits. EDCs can be transported long distances on water currents and can bioaccumulate in marine food webs. Two water currents around Newfoundland are suspected of transporting EDCs to adjacent marine ecosystems. Newfoundlanders may be exposed to EDCs through consumption of local seafood contaminated with EDCs. This study investigated EDC exposure in rural Newfoundland population by 1) testing local seafood species for the presence of EDCs, 2) determining the extent of local seafood consumption by surveying residents of two rural communities (Burin and New-Wes-Valley), 3) measuring serum thyroid hormones and plasma EDC concentrations in individuals who participated in the seafood consumption survey, and 4) exploring associations between seafood consumption, EDCs and thyroid hormones in participants. Liver samples from cod (Gadus morhua) and turbot (Scophthalmus maximus) showed the presence of polybrominated diphenyl ethers (PBDEs), which were commonly used as flame retardants. There were higher levels of PBDEs in fish samples from the west coast compared to those from the northeast coast of Newfoundland. Residents from the study communities consumed local cod more than any other species, and seafood consumption was higher in males than in females; and higher in older (> 50 years) than in younger (<50 years) participants. Increasing frequency of local cod consumption was positively associated with increasing PCB (-105, -118, -138, -170, -180 and ΣPCBs) and p,p’-DDE concentrations in participants. Therefore local cod consumption may be a source of exposure to these EDCs for rural Newfoundlanders. All participants had at least 11 EDCs present in their plasma; polychlorinated biphenyl (PCB), polybrominated biphenyl (PBB) and dichlorodiphenyldichloroethylene (p,p’-DDE) concentrations were higher in older participants, reflecting exposure to EDCs that have since been discontinued; ... |
format |
Thesis |
author |
Babichuk, Nicole Allen |
spellingShingle |
Babichuk, Nicole Allen A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland |
author_facet |
Babichuk, Nicole Allen |
author_sort |
Babichuk, Nicole Allen |
title |
A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland |
title_short |
A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland |
title_full |
A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland |
title_fullStr |
A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland |
title_full_unstemmed |
A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland |
title_sort |
fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural newfoundland |
publisher |
Memorial University of Newfoundland |
publishDate |
2021 |
url |
https://research.library.mun.ca/14789/ https://research.library.mun.ca/14789/1/thesis.pdf |
genre |
Gadus morhua Newfoundland Scophthalmus maximus Turbot |
genre_facet |
Gadus morhua Newfoundland Scophthalmus maximus Turbot |
op_relation |
https://research.library.mun.ca/14789/1/thesis.pdf Babichuk, Nicole Allen <https://research.library.mun.ca/view/creator_az/Babichuk=3ANicole_Allen=3A=3A.html> (2021) A fine kettle of fish: marine fish consumption, endocrine disrupting chemicals and thyroid hormones in rural Newfoundland. Doctoral (PhD) thesis, Memorial University of Newfoundland. |
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1778525194755768320 |