miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor
This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon’s photoperiodic re...
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ftmdpi:oai:mdpi.com:/2410-3888/8/7/345/ 2023-08-20T04:05:14+02:00 miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi agris 2023-06-30 application/pdf https://doi.org/10.3390/fishes8070345 EN eng Multidisciplinary Digital Publishing Institute Environment and Climate Change https://dx.doi.org/10.3390/fishes8070345 https://creativecommons.org/licenses/by/4.0/ Fishes; Volume 8; Issue 7; Pages: 345 photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon Text 2023 ftmdpi https://doi.org/10.3390/fishes8070345 2023-08-01T10:42:26Z This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon’s photoperiodic reproduction. These salmon were reared for 5 months under six different photoperiod regimens, including two with changing photoperiods (LL–SL = 24L:0D–8L:16D and SL–LL = 8L:16D–24L:0D) and four with constant photoperiods (24L:0D, 18L:6D, 12L:12D, and 8L:16D). The longer photoperiod groups (LL–SL and 24L:0D) were ultimately associated with higher gonadosomatic index (GSI) values and an increased proportion of mature fish relative to other exposure groups, indicating that the photoperiod positively impacted the Atlantic salmon’s gonadal development in RAS environments. Hypothalamic miR-155 expression in these Atlantic salmon was also found to be influenced by the photoperiod, showing a markedly decreased expression in salmon exposed to a long photoperiod and upregulation following rearing under a short photoperiod. Functionally, miR-155 was found to suppress the expression of gonadal axis-related genes, including FSH and GnRH, through its ability to target the brain-derived neurotrophic factor (BDNF) and to thereby regulate photoperiod reproduction. Overall, these results suggested that the photoperiod could regulate gonad development in Atlantic salmon with miRNA-155 being involved in this process by targeting the BDNF. Text Atlantic salmon Salmo salar MDPI Open Access Publishing Fishes 8 7 345 |
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MDPI Open Access Publishing |
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ftmdpi |
language |
English |
topic |
photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon |
spellingShingle |
photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor |
topic_facet |
photoperiod gonad development microRNA-155 recirculating aquaculture system Atlantic salmon |
description |
This study was designed to explore the impact of the photoperiod on the gonadal development and somatic growth of Atlantic salmon raised in recirculating aquaculture systems (RASs), with specific focus on the role that microRNA (miR)-155 plays as a regulator in the Atlantic salmon’s photoperiodic reproduction. These salmon were reared for 5 months under six different photoperiod regimens, including two with changing photoperiods (LL–SL = 24L:0D–8L:16D and SL–LL = 8L:16D–24L:0D) and four with constant photoperiods (24L:0D, 18L:6D, 12L:12D, and 8L:16D). The longer photoperiod groups (LL–SL and 24L:0D) were ultimately associated with higher gonadosomatic index (GSI) values and an increased proportion of mature fish relative to other exposure groups, indicating that the photoperiod positively impacted the Atlantic salmon’s gonadal development in RAS environments. Hypothalamic miR-155 expression in these Atlantic salmon was also found to be influenced by the photoperiod, showing a markedly decreased expression in salmon exposed to a long photoperiod and upregulation following rearing under a short photoperiod. Functionally, miR-155 was found to suppress the expression of gonadal axis-related genes, including FSH and GnRH, through its ability to target the brain-derived neurotrophic factor (BDNF) and to thereby regulate photoperiod reproduction. Overall, these results suggested that the photoperiod could regulate gonad development in Atlantic salmon with miRNA-155 being involved in this process by targeting the BDNF. |
format |
Text |
author |
Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi |
author_facet |
Teng Guo Yanfeng Wang Ping Jiang Jun Li Qinghua Liu Liang Chi |
author_sort |
Teng Guo |
title |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor |
title_short |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor |
title_full |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor |
title_fullStr |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor |
title_full_unstemmed |
miR-155 Regulates Photoperiod Induced Gonadal Development in Atlantic Salmon (Salmo salar) by Targeting Brain-Derived Neurotrophic Factor |
title_sort |
mir-155 regulates photoperiod induced gonadal development in atlantic salmon (salmo salar) by targeting brain-derived neurotrophic factor |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2023 |
url |
https://doi.org/10.3390/fishes8070345 |
op_coverage |
agris |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Fishes; Volume 8; Issue 7; Pages: 345 |
op_relation |
Environment and Climate Change https://dx.doi.org/10.3390/fishes8070345 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/fishes8070345 |
container_title |
Fishes |
container_volume |
8 |
container_issue |
7 |
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345 |
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1774715718231654400 |