Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis
Oral squamous cell carcinoma (SCC) is a common finding in domestic and wild felids. Only two cases of oral SCC have been reported in Lynx species (Lynx rufus and Lynx canadensis), at mandibular and gingival sites. In this study, we describe the first report of tongue SCC in a 15 years old female Eur...
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ftmdpi:oai:mdpi.com:/2306-7381/5/1/1/ 2023-08-20T04:10:26+02:00 Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis Gennaro Altamura Claudia Eleni Roberta Meoli Giusy Cardeti Klaus Friedrich Giuseppe Borzacchiello agris 2018-01-02 application/pdf https://doi.org/10.3390/vetsci5010001 EN eng Multidisciplinary Digital Publishing Institute https://dx.doi.org/10.3390/vetsci5010001 https://creativecommons.org/licenses/by/4.0/ Veterinary Sciences; Volume 5; Issue 1; Pages: 1 bobcat lynx papillomavirus squamous cell carcinoma Text 2018 ftmdpi https://doi.org/10.3390/vetsci5010001 2023-07-31T21:20:02Z Oral squamous cell carcinoma (SCC) is a common finding in domestic and wild felids. Only two cases of oral SCC have been reported in Lynx species (Lynx rufus and Lynx canadensis), at mandibular and gingival sites. In this study, we describe the first report of tongue SCC in a 15 years old female European lynx (Lynx lynx), along with viral investigations. Necropsy and histological analysis were performed and the presence of papillomavirus (PV) infection was investigated by ultrastructural and molecular methods. The lardaceous mass at tongue level was histologically diagnosed as moderately differentiated SCC. Typical microscopical features of SCC were also found in the retropharyngeal lymph node and at the pulmonary level. Neither viral DNA by PCR, nor viral particles by transmission electron microscopy were found. Despite that PV infection is associated with Felidae, this work reports the first description of tongue SCC in Lynx species, but no evidence of PV infection, suggesting that PV may not be involved in development of SCC in bobcat species. Text Lynx Lynx lynx lynx MDPI Open Access Publishing Veterinary Sciences 5 1 1 |
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bobcat lynx papillomavirus squamous cell carcinoma |
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bobcat lynx papillomavirus squamous cell carcinoma Gennaro Altamura Claudia Eleni Roberta Meoli Giusy Cardeti Klaus Friedrich Giuseppe Borzacchiello Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis |
topic_facet |
bobcat lynx papillomavirus squamous cell carcinoma |
description |
Oral squamous cell carcinoma (SCC) is a common finding in domestic and wild felids. Only two cases of oral SCC have been reported in Lynx species (Lynx rufus and Lynx canadensis), at mandibular and gingival sites. In this study, we describe the first report of tongue SCC in a 15 years old female European lynx (Lynx lynx), along with viral investigations. Necropsy and histological analysis were performed and the presence of papillomavirus (PV) infection was investigated by ultrastructural and molecular methods. The lardaceous mass at tongue level was histologically diagnosed as moderately differentiated SCC. Typical microscopical features of SCC were also found in the retropharyngeal lymph node and at the pulmonary level. Neither viral DNA by PCR, nor viral particles by transmission electron microscopy were found. Despite that PV infection is associated with Felidae, this work reports the first description of tongue SCC in Lynx species, but no evidence of PV infection, suggesting that PV may not be involved in development of SCC in bobcat species. |
format |
Text |
author |
Gennaro Altamura Claudia Eleni Roberta Meoli Giusy Cardeti Klaus Friedrich Giuseppe Borzacchiello |
author_facet |
Gennaro Altamura Claudia Eleni Roberta Meoli Giusy Cardeti Klaus Friedrich Giuseppe Borzacchiello |
author_sort |
Gennaro Altamura |
title |
Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis |
title_short |
Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis |
title_full |
Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis |
title_fullStr |
Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis |
title_full_unstemmed |
Tongue Squamous Cell Carcinoma in a European Lynx (Lynx Lynx): Papillomavirus Infection and Histologic Analysis |
title_sort |
tongue squamous cell carcinoma in a european lynx (lynx lynx): papillomavirus infection and histologic analysis |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2018 |
url |
https://doi.org/10.3390/vetsci5010001 |
op_coverage |
agris |
genre |
Lynx Lynx lynx lynx |
genre_facet |
Lynx Lynx lynx lynx |
op_source |
Veterinary Sciences; Volume 5; Issue 1; Pages: 1 |
op_relation |
https://dx.doi.org/10.3390/vetsci5010001 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/vetsci5010001 |
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Veterinary Sciences |
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5 |
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1 |
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1 |
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1774724620672303104 |