Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population
Mortality from cardiovascular diseases (CVDs) is higher in Russia compared to other European countries. High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation, and its elevated levels indicate increased CVD risks. We aim to describe the prevalence of low-grade systemic inflammat...
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ftmdpi:oai:mdpi.com:/2218-273X/13/5/835/ 2023-08-20T04:05:06+02:00 Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population Olga Mirolyubova Kamila Kholmatova Anna Postoeva Galina Kostrova Sofia Malyutina Alexander V. Kudryavtsev agris 2023-05-14 application/pdf https://doi.org/10.3390/biom13050835 EN eng Multidisciplinary Digital Publishing Institute Cellular Biochemistry https://dx.doi.org/10.3390/biom13050835 https://creativecommons.org/licenses/by/4.0/ Biomolecules; Volume 13; Issue 5; Pages: 835 low-grade systemic inflammation high-sensitivity C-reactive protein socio-demographic factors lifestyle abdominal obesity dyslipidemia hypertension smoking Russia Text 2023 ftmdpi https://doi.org/10.3390/biom13050835 2023-08-01T10:04:11Z Mortality from cardiovascular diseases (CVDs) is higher in Russia compared to other European countries. High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation, and its elevated levels indicate increased CVD risks. We aim to describe the prevalence of low-grade systemic inflammation (LGSI) and the associated factors in a Russian population. The Know Your Heart cross-sectional study was conducted in Arkhangelsk, Russia in 2015–2017 with a population sample aged 35–69 years (n = 2380). LGSI was defined as hs-CRP ≥ 2 and <10 mg/L, and its associations with socio-demographic, lifestyle, and cardiometabolic characteristics were analyzed. The prevalence of LGSI (age-standardized to European Standard Population 2013) was 34.1% (33.5% in men and 36.1% in women). In the total sample, the increased odds ratios (ORs) of LGSI were associated with abdominal obesity (2.1), smoking (1.9), dyslipidemia (1.5), pulmonary diseases (1.4), and hypertension (1.3); the decreased ORs were in women (0.6) and in married participants (0.6). In men, the ORs were higher with abdominal obesity (2.1), smoking (2.0), CVDs (1.5), and hazardous drinking (1.5); in women—with abdominal obesity (4.4) and pulmonary diseases (1.5). In conclusion, one-third of the adult population in Arkhangelsk had LGSI. Abdominal obesity was the strongest LGSI correlate in both sexes, while the profiles of other associated factors were different between men and women. Text Arkhangelsk MDPI Open Access Publishing Biomolecules 13 5 835 |
institution |
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MDPI Open Access Publishing |
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ftmdpi |
language |
English |
topic |
low-grade systemic inflammation high-sensitivity C-reactive protein socio-demographic factors lifestyle abdominal obesity dyslipidemia hypertension smoking Russia |
spellingShingle |
low-grade systemic inflammation high-sensitivity C-reactive protein socio-demographic factors lifestyle abdominal obesity dyslipidemia hypertension smoking Russia Olga Mirolyubova Kamila Kholmatova Anna Postoeva Galina Kostrova Sofia Malyutina Alexander V. Kudryavtsev Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
topic_facet |
low-grade systemic inflammation high-sensitivity C-reactive protein socio-demographic factors lifestyle abdominal obesity dyslipidemia hypertension smoking Russia |
description |
Mortality from cardiovascular diseases (CVDs) is higher in Russia compared to other European countries. High-sensitivity C-reactive protein (hs-CRP) is a biomarker of inflammation, and its elevated levels indicate increased CVD risks. We aim to describe the prevalence of low-grade systemic inflammation (LGSI) and the associated factors in a Russian population. The Know Your Heart cross-sectional study was conducted in Arkhangelsk, Russia in 2015–2017 with a population sample aged 35–69 years (n = 2380). LGSI was defined as hs-CRP ≥ 2 and <10 mg/L, and its associations with socio-demographic, lifestyle, and cardiometabolic characteristics were analyzed. The prevalence of LGSI (age-standardized to European Standard Population 2013) was 34.1% (33.5% in men and 36.1% in women). In the total sample, the increased odds ratios (ORs) of LGSI were associated with abdominal obesity (2.1), smoking (1.9), dyslipidemia (1.5), pulmonary diseases (1.4), and hypertension (1.3); the decreased ORs were in women (0.6) and in married participants (0.6). In men, the ORs were higher with abdominal obesity (2.1), smoking (2.0), CVDs (1.5), and hazardous drinking (1.5); in women—with abdominal obesity (4.4) and pulmonary diseases (1.5). In conclusion, one-third of the adult population in Arkhangelsk had LGSI. Abdominal obesity was the strongest LGSI correlate in both sexes, while the profiles of other associated factors were different between men and women. |
format |
Text |
author |
Olga Mirolyubova Kamila Kholmatova Anna Postoeva Galina Kostrova Sofia Malyutina Alexander V. Kudryavtsev |
author_facet |
Olga Mirolyubova Kamila Kholmatova Anna Postoeva Galina Kostrova Sofia Malyutina Alexander V. Kudryavtsev |
author_sort |
Olga Mirolyubova |
title |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_short |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_full |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_fullStr |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_full_unstemmed |
Socio-Demographic, Lifestyle, and Cardiometabolic Characteristics Associated with Low-Grade Systemic Inflammation in Russian Adult Population |
title_sort |
socio-demographic, lifestyle, and cardiometabolic characteristics associated with low-grade systemic inflammation in russian adult population |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2023 |
url |
https://doi.org/10.3390/biom13050835 |
op_coverage |
agris |
genre |
Arkhangelsk |
genre_facet |
Arkhangelsk |
op_source |
Biomolecules; Volume 13; Issue 5; Pages: 835 |
op_relation |
Cellular Biochemistry https://dx.doi.org/10.3390/biom13050835 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/biom13050835 |
container_title |
Biomolecules |
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13 |
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5 |
container_start_page |
835 |
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1774715540159332352 |