Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data
In this paper, we revealed the genetic structure and migration history of the Powassan virus (POWV) reconstructed based on 25 complete genomes available in NCBI and ViPR databases (accessed in June 2021). The usage of this data set allowed us to perform a more precise assessment of the evolutionary...
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ftmdpi:oai:mdpi.com:/2079-7737/10/12/1282/ 2023-08-20T04:05:34+02:00 Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data Artem N. Bondaryuk Tatiana E. Peretolchina Elena V. Romanova Anzhelika V. Yudinceva Evgeny I. Andaev Yurij S. Bukin agris 2021-12-06 application/pdf https://doi.org/10.3390/biology10121282 EN eng Multidisciplinary Digital Publishing Institute Evolutionary Biology https://dx.doi.org/10.3390/biology10121282 https://creativecommons.org/licenses/by/4.0/ Biology; Volume 10; Issue 12; Pages: 1282 Powassan virus Bayesian inference phylogenetics phylogeography evolutionary rate Text 2021 ftmdpi https://doi.org/10.3390/biology10121282 2023-08-01T03:28:28Z In this paper, we revealed the genetic structure and migration history of the Powassan virus (POWV) reconstructed based on 25 complete genomes available in NCBI and ViPR databases (accessed in June 2021). The usage of this data set allowed us to perform a more precise assessment of the evolutionary rate of this virus. In addition, we proposed a simple Bayesian technique for the evaluation and visualization of ‘temporal signal dynamics’ along the phylogenetic tree. We showed that the evolutionary rate value of POWV is 3.3 × 10−5 nucleotide substitution per site per year (95% HPD, 2.0 × 10−5–4.7 × 10−5), which is lower than values reported in the previous studies. Divergence of the most recent common ancestor (MRCA) of POWV into two independent genetic lineages most likely occurred in the period between 2600 and 6030 years ago. We assume that the divergence of the virus lineages happened due to the melting of glaciers about 12,000 years ago, which led to the disappearance of the Bering Land Bridge between Eurasia and North America (the modern Alaskan territory) and spatial division of the viral areal into two parts. Genomic data provide evidence of the virus migrations between two continents. The mean migration rate detected from the Far East of Russia to North America was one event per 1750 years. The migration to the opposite direction occurred approximately once per 475 years. Text Bering Land Bridge MDPI Open Access Publishing Biology 10 12 1282 |
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Powassan virus Bayesian inference phylogenetics phylogeography evolutionary rate |
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Powassan virus Bayesian inference phylogenetics phylogeography evolutionary rate Artem N. Bondaryuk Tatiana E. Peretolchina Elena V. Romanova Anzhelika V. Yudinceva Evgeny I. Andaev Yurij S. Bukin Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data |
topic_facet |
Powassan virus Bayesian inference phylogenetics phylogeography evolutionary rate |
description |
In this paper, we revealed the genetic structure and migration history of the Powassan virus (POWV) reconstructed based on 25 complete genomes available in NCBI and ViPR databases (accessed in June 2021). The usage of this data set allowed us to perform a more precise assessment of the evolutionary rate of this virus. In addition, we proposed a simple Bayesian technique for the evaluation and visualization of ‘temporal signal dynamics’ along the phylogenetic tree. We showed that the evolutionary rate value of POWV is 3.3 × 10−5 nucleotide substitution per site per year (95% HPD, 2.0 × 10−5–4.7 × 10−5), which is lower than values reported in the previous studies. Divergence of the most recent common ancestor (MRCA) of POWV into two independent genetic lineages most likely occurred in the period between 2600 and 6030 years ago. We assume that the divergence of the virus lineages happened due to the melting of glaciers about 12,000 years ago, which led to the disappearance of the Bering Land Bridge between Eurasia and North America (the modern Alaskan territory) and spatial division of the viral areal into two parts. Genomic data provide evidence of the virus migrations between two continents. The mean migration rate detected from the Far East of Russia to North America was one event per 1750 years. The migration to the opposite direction occurred approximately once per 475 years. |
format |
Text |
author |
Artem N. Bondaryuk Tatiana E. Peretolchina Elena V. Romanova Anzhelika V. Yudinceva Evgeny I. Andaev Yurij S. Bukin |
author_facet |
Artem N. Bondaryuk Tatiana E. Peretolchina Elena V. Romanova Anzhelika V. Yudinceva Evgeny I. Andaev Yurij S. Bukin |
author_sort |
Artem N. Bondaryuk |
title |
Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data |
title_short |
Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data |
title_full |
Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data |
title_fullStr |
Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data |
title_full_unstemmed |
Phylogeography and Re-Evaluation of Evolutionary Rate of Powassan Virus Using Complete Genome Data |
title_sort |
phylogeography and re-evaluation of evolutionary rate of powassan virus using complete genome data |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2021 |
url |
https://doi.org/10.3390/biology10121282 |
op_coverage |
agris |
genre |
Bering Land Bridge |
genre_facet |
Bering Land Bridge |
op_source |
Biology; Volume 10; Issue 12; Pages: 1282 |
op_relation |
Evolutionary Biology https://dx.doi.org/10.3390/biology10121282 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/biology10121282 |
container_title |
Biology |
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10 |
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12 |
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1282 |
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1774716132560732160 |