Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames
The fishery industry generates large amounts of waste (20–75% (w/w) of the total caught fish weight). The recovery of bioactive compounds from residues and their incorporation in cosmetics represents a promising market opportunity and may contribute to a sustainable valorisation of the sector. In th...
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ftmdpi:oai:mdpi.com:/2076-3921/11/10/1925/ 2023-08-20T04:06:38+02:00 Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames Martim Cardeira Ana Bernardo Inês C. Leonardo Frédéric B. Gaspar Marta Marques Rodrigo Melgosa Alexandre Paiva Pedro Simões Naiara Fernández Ana Teresa Serra agris 2022-09-28 application/pdf https://doi.org/10.3390/antiox11101925 EN eng Multidisciplinary Digital Publishing Institute Natural and Synthetic Antioxidants https://dx.doi.org/10.3390/antiox11101925 https://creativecommons.org/licenses/by/4.0/ Antioxidants; Volume 11; Issue 10; Pages: 1925 fish waste streams valorisation antioxidant activity anti-inflammatory activity antimicrobial activity anti-ageing anti-hyperpigmentation cosmeceuticals Text 2022 ftmdpi https://doi.org/10.3390/antiox11101925 2023-08-01T06:40:04Z The fishery industry generates large amounts of waste (20–75% (w/w) of the total caught fish weight). The recovery of bioactive compounds from residues and their incorporation in cosmetics represents a promising market opportunity and may contribute to a sustainable valorisation of the sector. In this work, protein-rich extracts obtained by high-pressure technologies (supercritical CO2 and subcritical water) from sardine (Sardina pilchardus) waste and codfish (Gadus morhua) frames were characterized regarding their cosmeceutical potential. Antioxidant, anti-inflammatory and antibacterial activities were evaluated through chemical (ORAC assay), enzymatic (inhibition of elastase and tyrosinase), antimicrobial susceptibility (Klebsiella pneumoniae, Staphylococcus aureus and Cutibacterium acnes) and cell-based (in keratinocytes-HaCaT) assays. Sardine extracts presented the highest antibacterial activity, and the extract obtained using higher extraction temperatures (250 °C) and without the defatting step demonstrated the lowest minimum inhibitory concentration (MIC) values (1.17; 4.6; 0.59 mg/mL for K. pneumoniae, S. aureus and C. acnes, respectively). Codfish samples extracted at lower temperatures (90 °C) were the most effective anti-inflammatory agents (a concentration of 0.75 mg/mL reduced IL-8 and IL-6 levels by 58% and 47%, respectively, relative to the positive control). Threonine, valine, leucine, arginine and total protein content in the extracts were highlighted to present a high correlation with the reported bioactivities (R2 ≥ 0.7). These results support the potential application of extracts obtained from fishery industry wastes in cosmeceutical products with bioactive activities. Text Gadus morhua MDPI Open Access Publishing Antioxidants 11 10 1925 |
institution |
Open Polar |
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MDPI Open Access Publishing |
op_collection_id |
ftmdpi |
language |
English |
topic |
fish waste streams valorisation antioxidant activity anti-inflammatory activity antimicrobial activity anti-ageing anti-hyperpigmentation cosmeceuticals |
spellingShingle |
fish waste streams valorisation antioxidant activity anti-inflammatory activity antimicrobial activity anti-ageing anti-hyperpigmentation cosmeceuticals Martim Cardeira Ana Bernardo Inês C. Leonardo Frédéric B. Gaspar Marta Marques Rodrigo Melgosa Alexandre Paiva Pedro Simões Naiara Fernández Ana Teresa Serra Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
topic_facet |
fish waste streams valorisation antioxidant activity anti-inflammatory activity antimicrobial activity anti-ageing anti-hyperpigmentation cosmeceuticals |
description |
The fishery industry generates large amounts of waste (20–75% (w/w) of the total caught fish weight). The recovery of bioactive compounds from residues and their incorporation in cosmetics represents a promising market opportunity and may contribute to a sustainable valorisation of the sector. In this work, protein-rich extracts obtained by high-pressure technologies (supercritical CO2 and subcritical water) from sardine (Sardina pilchardus) waste and codfish (Gadus morhua) frames were characterized regarding their cosmeceutical potential. Antioxidant, anti-inflammatory and antibacterial activities were evaluated through chemical (ORAC assay), enzymatic (inhibition of elastase and tyrosinase), antimicrobial susceptibility (Klebsiella pneumoniae, Staphylococcus aureus and Cutibacterium acnes) and cell-based (in keratinocytes-HaCaT) assays. Sardine extracts presented the highest antibacterial activity, and the extract obtained using higher extraction temperatures (250 °C) and without the defatting step demonstrated the lowest minimum inhibitory concentration (MIC) values (1.17; 4.6; 0.59 mg/mL for K. pneumoniae, S. aureus and C. acnes, respectively). Codfish samples extracted at lower temperatures (90 °C) were the most effective anti-inflammatory agents (a concentration of 0.75 mg/mL reduced IL-8 and IL-6 levels by 58% and 47%, respectively, relative to the positive control). Threonine, valine, leucine, arginine and total protein content in the extracts were highlighted to present a high correlation with the reported bioactivities (R2 ≥ 0.7). These results support the potential application of extracts obtained from fishery industry wastes in cosmeceutical products with bioactive activities. |
format |
Text |
author |
Martim Cardeira Ana Bernardo Inês C. Leonardo Frédéric B. Gaspar Marta Marques Rodrigo Melgosa Alexandre Paiva Pedro Simões Naiara Fernández Ana Teresa Serra |
author_facet |
Martim Cardeira Ana Bernardo Inês C. Leonardo Frédéric B. Gaspar Marta Marques Rodrigo Melgosa Alexandre Paiva Pedro Simões Naiara Fernández Ana Teresa Serra |
author_sort |
Martim Cardeira |
title |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
title_short |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
title_full |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
title_fullStr |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
title_full_unstemmed |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
title_sort |
cosmeceutical potential of extracts derived from fishery industry residues: sardine wastes and codfish frames |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2022 |
url |
https://doi.org/10.3390/antiox11101925 |
op_coverage |
agris |
genre |
Gadus morhua |
genre_facet |
Gadus morhua |
op_source |
Antioxidants; Volume 11; Issue 10; Pages: 1925 |
op_relation |
Natural and Synthetic Antioxidants https://dx.doi.org/10.3390/antiox11101925 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/antiox11101925 |
container_title |
Antioxidants |
container_volume |
11 |
container_issue |
10 |
container_start_page |
1925 |
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1774717859996368896 |