A Polyprotein-Expressing Salmonid Alphavirus Replicon Induces Modest Protection in Atlantic Salmon (Salmo Salar) Against Infectious Pancreatic Necrosis

• Published in: Viruses
• Main Authors: Azila Abdullah, Christel Olsen, Kjartan Hodneland, Espen Rimstad
• Format: Text
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2015
• Subjects: infectious pancreatic necrosis; Atlantic salmon; vaccination; alphavirus replicon; Sav’; Salmo salar
• Online Access: https://doi.org/10.3390/v7010252

Vaccination is an important strategy for the control and prevention of infectious pancreatic necrosis (IPN) in farmed Atlantic salmon (Salmo salar) in the post-smolt stage in sea-water. In this study, a heterologous gene expression system, based on a replicon construct of salmonid alphavirus (SAV),...