Sea Lice (Lepeophtheirus salmonis) Infestation Reduces the Ability of Peripheral Blood Monocytic Cells (PBMCs) to Respond to and Control Replication of Salmonid Alphavirus in Atlantic Salmon (Salmo salar L.)

• Published in: Viruses
• Main Authors: Amr A. A. Gamil, Koestan Gadan, Elisabeth Gislefoss, Øystein Evensen
• Format: Text
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2020
• Subjects: Lepeophtheirus salmonis; innate immune responses; salmonid alphavirus; interaction; Sav’; Atlantic salmon; Salmo salar
• Online Access: https://doi.org/10.3390/v12121450

Here we have studied the impact of lice (Lepeophtheirus salmonis) infestation of donor fish on the ability of isolated peripheral blood monocytes (PBMCs) to control the replication of salmonid alphavirus (SAV) ex vivo. PBMCs were collected by Percoll gradients at eight and nine weeks post copepodid...