Surveillance for Adenoviruses in Bats in Italy
Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in...
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ftmdpi:oai:mdpi.com:/1999-4915/11/6/523/ 2023-08-20T04:09:18+02:00 Surveillance for Adenoviruses in Bats in Italy Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli agris 2019-06-06 application/pdf https://doi.org/10.3390/v11060523 EN eng Multidisciplinary Digital Publishing Institute Animal Viruses https://dx.doi.org/10.3390/v11060523 https://creativecommons.org/licenses/by/4.0/ Viruses; Volume 11; Issue 6; Pages: 523 bat adenovirus mastadenovirus aviadenovirus sequence NGS Italy phylogenetic analysis Text 2019 ftmdpi https://doi.org/10.3390/v11060523 2023-07-31T22:20:19Z Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a Pipistrellus kuhlii, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the Pipistrellus pipistrellus strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts. Text Pipistrellus pipistrellus MDPI Open Access Publishing Viruses 11 6 523 |
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Open Polar |
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MDPI Open Access Publishing |
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ftmdpi |
language |
English |
topic |
bat adenovirus mastadenovirus aviadenovirus sequence NGS Italy phylogenetic analysis |
spellingShingle |
bat adenovirus mastadenovirus aviadenovirus sequence NGS Italy phylogenetic analysis Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli Surveillance for Adenoviruses in Bats in Italy |
topic_facet |
bat adenovirus mastadenovirus aviadenovirus sequence NGS Italy phylogenetic analysis |
description |
Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a Pipistrellus kuhlii, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the Pipistrellus pipistrellus strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts. |
format |
Text |
author |
Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli |
author_facet |
Georgia Diakoudi Gianvito Lanave Ana Moreno Chiara Chiapponi Enrica Sozzi Alice Prosperi Vittorio Larocca Michele Losurdo Nicola Decaro Vito Martella Antonio Lavazza Davide Lelli |
author_sort |
Georgia Diakoudi |
title |
Surveillance for Adenoviruses in Bats in Italy |
title_short |
Surveillance for Adenoviruses in Bats in Italy |
title_full |
Surveillance for Adenoviruses in Bats in Italy |
title_fullStr |
Surveillance for Adenoviruses in Bats in Italy |
title_full_unstemmed |
Surveillance for Adenoviruses in Bats in Italy |
title_sort |
surveillance for adenoviruses in bats in italy |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2019 |
url |
https://doi.org/10.3390/v11060523 |
op_coverage |
agris |
genre |
Pipistrellus pipistrellus |
genre_facet |
Pipistrellus pipistrellus |
op_source |
Viruses; Volume 11; Issue 6; Pages: 523 |
op_relation |
Animal Viruses https://dx.doi.org/10.3390/v11060523 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/v11060523 |
container_title |
Viruses |
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11 |
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6 |
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523 |
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1774722153705373696 |