The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis
We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First...
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ftmdpi:oai:mdpi.com:/1660-4601/15/3/539/ 2023-08-20T04:06:31+02:00 The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis Lesya Marushka Xuefeng Hu Malek Batal Tonio Sadik Harold Schwartz Amy Ing Karen Fediuk Constantine Tikhonov Hing Chan agris 2018-03-17 application/pdf https://doi.org/10.3390/ijerph15030539 EN eng Multidisciplinary Digital Publishing Institute Environmental Health https://dx.doi.org/10.3390/ijerph15030539 https://creativecommons.org/licenses/by/4.0/ International Journal of Environmental Research and Public Health; Volume 15; Issue 3; Pages: 539 persistent organic pollutants type 2 diabetes fish consumption difference in difference model long chain n-3 fatty acids First Nations Text 2018 ftmdpi https://doi.org/10.3390/ijerph15030539 2023-07-31T21:26:07Z We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First Nations Food Nutrition and Environment Study, a cross-sectional study of 706 Manitoba and 1429 Ontario FNs were analyzed. The consumption of fish was estimated using a food frequency questionnaire. Fish samples were analyzed for dichloro diphenyldichloro ethylene (DDE) and polychlorinated biphenyls (PCBs) content. Difference in difference model results showed that persistent organic pollutant (POP) exposure was positively associated with T2D in a dose-response manner. Stronger positive associations were found among females (OR = 14.96 (3.72–60.11)) than in males (OR = 2.85 (1.14–8.04)). The breakpoints for DDE and PCB intake were 2.11 ng/kg/day and 1.47 ng/kg/day, respectively. Each further 1 ng/kg/day increase in DDE and PCB intake increased the risk of T2D with ORs 2.29 (1.26–4.17) and 1.44 (1.09–1.89), respectively. Our findings suggest that the balance of risk and benefits associated with fish consumption is highly dependent on the regional POP concentrations in fish. Text First Nations MDPI Open Access Publishing Canada International Journal of Environmental Research and Public Health 15 3 539 |
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English |
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persistent organic pollutants type 2 diabetes fish consumption difference in difference model long chain n-3 fatty acids First Nations |
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persistent organic pollutants type 2 diabetes fish consumption difference in difference model long chain n-3 fatty acids First Nations Lesya Marushka Xuefeng Hu Malek Batal Tonio Sadik Harold Schwartz Amy Ing Karen Fediuk Constantine Tikhonov Hing Chan The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
topic_facet |
persistent organic pollutants type 2 diabetes fish consumption difference in difference model long chain n-3 fatty acids First Nations |
description |
We previously studied the association between fish consumption and prevalence of type 2 diabetes (T2D) in Manitoba and Ontario First Nations (FNs), Canada and found different results. In this study, we used a difference in difference model to analyze the data. Dietary and health data from the First Nations Food Nutrition and Environment Study, a cross-sectional study of 706 Manitoba and 1429 Ontario FNs were analyzed. The consumption of fish was estimated using a food frequency questionnaire. Fish samples were analyzed for dichloro diphenyldichloro ethylene (DDE) and polychlorinated biphenyls (PCBs) content. Difference in difference model results showed that persistent organic pollutant (POP) exposure was positively associated with T2D in a dose-response manner. Stronger positive associations were found among females (OR = 14.96 (3.72–60.11)) than in males (OR = 2.85 (1.14–8.04)). The breakpoints for DDE and PCB intake were 2.11 ng/kg/day and 1.47 ng/kg/day, respectively. Each further 1 ng/kg/day increase in DDE and PCB intake increased the risk of T2D with ORs 2.29 (1.26–4.17) and 1.44 (1.09–1.89), respectively. Our findings suggest that the balance of risk and benefits associated with fish consumption is highly dependent on the regional POP concentrations in fish. |
format |
Text |
author |
Lesya Marushka Xuefeng Hu Malek Batal Tonio Sadik Harold Schwartz Amy Ing Karen Fediuk Constantine Tikhonov Hing Chan |
author_facet |
Lesya Marushka Xuefeng Hu Malek Batal Tonio Sadik Harold Schwartz Amy Ing Karen Fediuk Constantine Tikhonov Hing Chan |
author_sort |
Lesya Marushka |
title |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_short |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_full |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_fullStr |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_full_unstemmed |
The Relationship between Persistent Organic Pollutants Exposure and Type 2 Diabetes among First Nations in Ontario and Manitoba, Canada: A Difference in Difference Analysis |
title_sort |
relationship between persistent organic pollutants exposure and type 2 diabetes among first nations in ontario and manitoba, canada: a difference in difference analysis |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2018 |
url |
https://doi.org/10.3390/ijerph15030539 |
op_coverage |
agris |
geographic |
Canada |
geographic_facet |
Canada |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
International Journal of Environmental Research and Public Health; Volume 15; Issue 3; Pages: 539 |
op_relation |
Environmental Health https://dx.doi.org/10.3390/ijerph15030539 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/ijerph15030539 |
container_title |
International Journal of Environmental Research and Public Health |
container_volume |
15 |
container_issue |
3 |
container_start_page |
539 |
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1774717626127220736 |