Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa

3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them we...

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Published in:Marine Drugs
Main Authors: Christoph Timm, Thorsten Mordhorst, Matthias Köck
Format: Text
Language:English
Published: Molecular Diversity Preservation International 2010
Subjects:
Online Access:https://doi.org/10.3390/md8030483
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author Christoph Timm
Thorsten Mordhorst
Matthias Köck
author_facet Christoph Timm
Thorsten Mordhorst
Matthias Köck
author_sort Christoph Timm
collection MDPI Open Access Publishing
container_issue 3
container_start_page 483
container_title Marine Drugs
container_volume 8
description 3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them were isolated from the Arctic sponge Haliclona viscosa collected in Spitsbergen, Norway. In this article we report the syntheses of these secondary metabolites from Haliclona viscosa and related compounds and give a short overview of the bioactivity.
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genre Arctic
Spitsbergen
genre_facet Arctic
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geographic Arctic
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op_doi https://doi.org/10.3390/md8030483
op_relation https://dx.doi.org/10.3390/md8030483
op_rights https://creativecommons.org/licenses/by/3.0/
op_source Marine Drugs; Volume 8; Issue 3; Pages: 483-497
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spelling ftmdpi:oai:mdpi.com:/1660-3397/8/3/483/ 2025-01-16T20:19:33+00:00 Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa Christoph Timm Thorsten Mordhorst Matthias Köck agris 2010-03-05 application/pdf https://doi.org/10.3390/md8030483 EN eng Molecular Diversity Preservation International https://dx.doi.org/10.3390/md8030483 https://creativecommons.org/licenses/by/3.0/ Marine Drugs; Volume 8; Issue 3; Pages: 483-497 3-alkyl pyridinium alkaloids; Haliclona viscosa synthesis marine natural products Text 2010 ftmdpi https://doi.org/10.3390/md8030483 2023-07-31T20:24:16Z 3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them were isolated from the Arctic sponge Haliclona viscosa collected in Spitsbergen, Norway. In this article we report the syntheses of these secondary metabolites from Haliclona viscosa and related compounds and give a short overview of the bioactivity. Text Arctic Spitsbergen MDPI Open Access Publishing Arctic Norway Marine Drugs 8 3 483 497
spellingShingle 3-alkyl pyridinium alkaloids; Haliclona viscosa
synthesis
marine natural products
Christoph Timm
Thorsten Mordhorst
Matthias Köck
Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_full Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_fullStr Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_full_unstemmed Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_short Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa
title_sort synthesis of 3-alkyl pyridinium alkaloids from the arctic sponge haliclona viscosa
topic 3-alkyl pyridinium alkaloids; Haliclona viscosa
synthesis
marine natural products
topic_facet 3-alkyl pyridinium alkaloids; Haliclona viscosa
synthesis
marine natural products
url https://doi.org/10.3390/md8030483