The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research
The world-famous Antarctic krill (Euphausia superba) plays a fundamental role in the Antarctic food chain. It resides in cold environments with the most abundant biomass to support the Antarctic ecology and fisheries. Here, we performed the first genome survey of the Antarctic krill, with genomic ev...
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ftmdpi:oai:mdpi.com:/1660-3397/18/4/185/ 2023-08-20T04:01:39+02:00 The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research Yuting Huang Chao Bian Zhaoqun Liu Lingling Wang Changhu Xue Hongliang Huang Yunhai Yi Xinxin You Wei Song Xiangzhao Mao Linsheng Song Qiong Shi agris 2020-03-31 application/pdf https://doi.org/10.3390/md18040185 EN eng Multidisciplinary Digital Publishing Institute https://dx.doi.org/10.3390/md18040185 https://creativecommons.org/licenses/by/4.0/ Marine Drugs; Volume 18; Issue 4; Pages: 185 Antarctic krill (Euphausia superba) genome survey mitochondrial genome whiteleg shrimp ( Penaeus vannamei ) antimicrobial peptide (AMP) antihypertensive peptide (AHTP) Text 2020 ftmdpi https://doi.org/10.3390/md18040185 2023-07-31T23:18:45Z The world-famous Antarctic krill (Euphausia superba) plays a fundamental role in the Antarctic food chain. It resides in cold environments with the most abundant biomass to support the Antarctic ecology and fisheries. Here, we performed the first genome survey of the Antarctic krill, with genomic evidence for its estimated genome size of 42.1 gigabases (Gb). Such a large genome, however, is beyond our present capability to obtain a good assembly, although our sequencing data are a valuable genetic resource for subsequent polar biomedical research. We extracted 13 typical protein-coding gene sequences of the mitochondrial genome and analyzed simple sequence repeats (SSRs), which are useful for species identification and origin determination. Meanwhile, we conducted a high-throughput comparative identification of putative antimicrobial peptides (AMPs) and antihypertensive peptides (AHTPs) from whole-body transcriptomes of the Antarctic krill and its well-known counterpart, the whiteleg shrimp (Penaeus vannamei; resident in warm waters). Related data revealed that AMPs/AMP precursors and AHTPs were generally conserved, with interesting variations between the two crustacean species. In summary, as the first report of estimated genome size of the Antarctic krill, our present genome survey data provide a foundation for further biological research into this polar species. Our preliminary investigations on bioactive peptides will bring a new perspective for the in-depth development of novel marine drugs. Text Antarc* Antarctic Antarctic Krill Euphausia superba MDPI Open Access Publishing Antarctic The Antarctic Marine Drugs 18 4 185 |
institution |
Open Polar |
collection |
MDPI Open Access Publishing |
op_collection_id |
ftmdpi |
language |
English |
topic |
Antarctic krill (Euphausia superba) genome survey mitochondrial genome whiteleg shrimp ( Penaeus vannamei ) antimicrobial peptide (AMP) antihypertensive peptide (AHTP) |
spellingShingle |
Antarctic krill (Euphausia superba) genome survey mitochondrial genome whiteleg shrimp ( Penaeus vannamei ) antimicrobial peptide (AMP) antihypertensive peptide (AHTP) Yuting Huang Chao Bian Zhaoqun Liu Lingling Wang Changhu Xue Hongliang Huang Yunhai Yi Xinxin You Wei Song Xiangzhao Mao Linsheng Song Qiong Shi The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research |
topic_facet |
Antarctic krill (Euphausia superba) genome survey mitochondrial genome whiteleg shrimp ( Penaeus vannamei ) antimicrobial peptide (AMP) antihypertensive peptide (AHTP) |
description |
The world-famous Antarctic krill (Euphausia superba) plays a fundamental role in the Antarctic food chain. It resides in cold environments with the most abundant biomass to support the Antarctic ecology and fisheries. Here, we performed the first genome survey of the Antarctic krill, with genomic evidence for its estimated genome size of 42.1 gigabases (Gb). Such a large genome, however, is beyond our present capability to obtain a good assembly, although our sequencing data are a valuable genetic resource for subsequent polar biomedical research. We extracted 13 typical protein-coding gene sequences of the mitochondrial genome and analyzed simple sequence repeats (SSRs), which are useful for species identification and origin determination. Meanwhile, we conducted a high-throughput comparative identification of putative antimicrobial peptides (AMPs) and antihypertensive peptides (AHTPs) from whole-body transcriptomes of the Antarctic krill and its well-known counterpart, the whiteleg shrimp (Penaeus vannamei; resident in warm waters). Related data revealed that AMPs/AMP precursors and AHTPs were generally conserved, with interesting variations between the two crustacean species. In summary, as the first report of estimated genome size of the Antarctic krill, our present genome survey data provide a foundation for further biological research into this polar species. Our preliminary investigations on bioactive peptides will bring a new perspective for the in-depth development of novel marine drugs. |
format |
Text |
author |
Yuting Huang Chao Bian Zhaoqun Liu Lingling Wang Changhu Xue Hongliang Huang Yunhai Yi Xinxin You Wei Song Xiangzhao Mao Linsheng Song Qiong Shi |
author_facet |
Yuting Huang Chao Bian Zhaoqun Liu Lingling Wang Changhu Xue Hongliang Huang Yunhai Yi Xinxin You Wei Song Xiangzhao Mao Linsheng Song Qiong Shi |
author_sort |
Yuting Huang |
title |
The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research |
title_short |
The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research |
title_full |
The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research |
title_fullStr |
The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research |
title_full_unstemmed |
The First Genome Survey of the Antarctic Krill (Euphausia superba) Provides a Valuable Genetic Resource for Polar Biomedical Research |
title_sort |
first genome survey of the antarctic krill (euphausia superba) provides a valuable genetic resource for polar biomedical research |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2020 |
url |
https://doi.org/10.3390/md18040185 |
op_coverage |
agris |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic Antarctic Krill Euphausia superba |
genre_facet |
Antarc* Antarctic Antarctic Krill Euphausia superba |
op_source |
Marine Drugs; Volume 18; Issue 4; Pages: 185 |
op_relation |
https://dx.doi.org/10.3390/md18040185 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/md18040185 |
container_title |
Marine Drugs |
container_volume |
18 |
container_issue |
4 |
container_start_page |
185 |
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1774724909645168640 |