Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review
One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a...
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ftmdpi:oai:mdpi.com:/1660-3397/18/1/41/ 2023-08-20T04:04:35+02:00 Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama agris 2020-01-06 application/pdf https://doi.org/10.3390/md18010041 EN eng Multidisciplinary Digital Publishing Institute https://dx.doi.org/10.3390/md18010041 https://creativecommons.org/licenses/by/4.0/ Marine Drugs; Volume 18; Issue 1; Pages: 41 Sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory Text 2020 ftmdpi https://doi.org/10.3390/md18010041 2023-07-31T22:58:14Z One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton, as well as their reported biological activities covering a period of about two decades (1998–2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities. Text Arctic MDPI Open Access Publishing Arctic Pacific Marine Drugs 18 1 41 |
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MDPI Open Access Publishing |
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language |
English |
topic |
Sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory |
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Sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
topic_facet |
Sacrphyton soft coral terpenoids antimicrobial antitumor antidiabetic anti-inflammatory |
description |
One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton, as well as their reported biological activities covering a period of about two decades (1998–2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities. |
format |
Text |
author |
Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama |
author_facet |
Yasmin A. Elkhawas Ahmed M. Elissawy Mohamed S. Elnaggar Nada M. Mostafa Eman Al-Sayed Mokhtar M. Bishr Abdel Nasser B. Singab Osama M. Salama |
author_sort |
Yasmin A. Elkhawas |
title |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_short |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_full |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_fullStr |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_full_unstemmed |
Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review |
title_sort |
chemical diversity in species belonging to soft coral genus sacrophyton and its impact on biological activity: a review |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2020 |
url |
https://doi.org/10.3390/md18010041 |
op_coverage |
agris |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Marine Drugs; Volume 18; Issue 1; Pages: 41 |
op_relation |
https://dx.doi.org/10.3390/md18010041 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/md18010041 |
container_title |
Marine Drugs |
container_volume |
18 |
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1 |
container_start_page |
41 |
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