Secondary Metabolites from Polar Organisms

Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms,...

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Bibliographic Details
Published in:Marine Drugs
Main Authors: Yuan Tian, Yan-Ling Li, Feng-Chun Zhao
Format: Text
Language:English
Published: Multidisciplinary Digital Publishing Institute 2017
Subjects:
natural products
secondary metabolism
structure elucidation
biological activity
biosynthesis
chemical synthesis
Antarctic
Arctic
The Antarctic
Antarc*
Online Access:https://doi.org/10.3390/md15030028
Description
Summary:Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms, lichen, moss and marine faunas. The structures of the new compounds and details of the source organism, along with any relevant biological activities are presented. Where reported, synthetic and biosynthetic studies on the polar metabolites have also been included.

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