Prokaryotic Expression, Purification, and Antibacterial Activity of the Hepcidin Peptide of Crescent Sweetlips (Plectorhinchus cinctus)

• Published in: Current Issues in Molecular Biology
• Main Authors: Peixin Wang, Zhongjing Lin, Shaoling Lin, Baodong Zheng, Yi Zhang, Jiamiao Hu
• Format: Text
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2023
• Subjects: crescent sweetlips; hepcidin; soluble expression; optimization; antibacterial activity; Arctic; Ida
• Online Access: https://doi.org/10.3390/cimb45090456

The hepcidin peptide of crescent sweetlips (Plectorhinchus cinctus) is a cysteine-rich, cationic antimicrobial peptide that plays a crucial role in the innate immune system’s defense against invading microbes. The aim of this study was to identify the optimal parameters for prokaryotic expression an...