Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni
Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in...
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ftmdpi:oai:mdpi.com:/1422-0067/23/21/12799/ 2023-08-20T04:01:57+02:00 Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni Rigers Bakiu Sara Pacchini Elisabetta Piva Sophia Schumann Anna Maria Tolomeo Diana Ferro Paola Irato Gianfranco Santovito agris 2022-10-24 application/pdf https://doi.org/10.3390/ijms232112799 EN eng Multidisciplinary Digital Publishing Institute Molecular Toxicology https://dx.doi.org/10.3390/ijms232112799 https://creativecommons.org/licenses/by/4.0/ International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12799 Antarctica antioxidants cadmium copper fish metallothioneins Text 2022 ftmdpi https://doi.org/10.3390/ijms232112799 2023-08-01T07:01:04Z Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in its tissues. Specimens of this Antarctic fish were collected from Terra Nova Bay (Ross Sea) and used for a metal exposure experiment in controlled laboratory conditions. The two treatments led to a significant accumulation of both metals and increased gene transcription only for the MT-1. The biosynthesis of MTs was verified especially in specimens exposed to Cd, but most of these proteins were soon oxidized, probably because they were involved in cell protection against oxidative stress risk by scavenging reactive oxygen species. The obtained data highlighted the phenotypic plasticity of T. hansoni, a species that evolved in an environment characterized by naturally high concentrations of Cu and Cd, and maybe the possibility for the Antarctic fish to face the challenges of a world that is becoming more toxic every day. Text Antarc* Antarctic Antarctica Ross Sea MDPI Open Access Publishing Antarctic Ross Sea Terra Nova Bay The Antarctic International Journal of Molecular Sciences 23 21 12799 |
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Open Polar |
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MDPI Open Access Publishing |
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ftmdpi |
language |
English |
topic |
Antarctica antioxidants cadmium copper fish metallothioneins |
spellingShingle |
Antarctica antioxidants cadmium copper fish metallothioneins Rigers Bakiu Sara Pacchini Elisabetta Piva Sophia Schumann Anna Maria Tolomeo Diana Ferro Paola Irato Gianfranco Santovito Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
topic_facet |
Antarctica antioxidants cadmium copper fish metallothioneins |
description |
Metal bioaccumulation and metallothionein (MT) expression were investigated in the gills and liver of the red-blooded Antarctic teleost Trematomus hansoni to evaluate the possibility for this species to face, with adequate physiological responses, an increase of copper and cadmium concentrations in its tissues. Specimens of this Antarctic fish were collected from Terra Nova Bay (Ross Sea) and used for a metal exposure experiment in controlled laboratory conditions. The two treatments led to a significant accumulation of both metals and increased gene transcription only for the MT-1. The biosynthesis of MTs was verified especially in specimens exposed to Cd, but most of these proteins were soon oxidized, probably because they were involved in cell protection against oxidative stress risk by scavenging reactive oxygen species. The obtained data highlighted the phenotypic plasticity of T. hansoni, a species that evolved in an environment characterized by naturally high concentrations of Cu and Cd, and maybe the possibility for the Antarctic fish to face the challenges of a world that is becoming more toxic every day. |
format |
Text |
author |
Rigers Bakiu Sara Pacchini Elisabetta Piva Sophia Schumann Anna Maria Tolomeo Diana Ferro Paola Irato Gianfranco Santovito |
author_facet |
Rigers Bakiu Sara Pacchini Elisabetta Piva Sophia Schumann Anna Maria Tolomeo Diana Ferro Paola Irato Gianfranco Santovito |
author_sort |
Rigers Bakiu |
title |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_short |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_full |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_fullStr |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_full_unstemmed |
Metallothionein Expression as a Physiological Response against Metal Toxicity in the Striped Rockcod Trematomus hansoni |
title_sort |
metallothionein expression as a physiological response against metal toxicity in the striped rockcod trematomus hansoni |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2022 |
url |
https://doi.org/10.3390/ijms232112799 |
op_coverage |
agris |
geographic |
Antarctic Ross Sea Terra Nova Bay The Antarctic |
geographic_facet |
Antarctic Ross Sea Terra Nova Bay The Antarctic |
genre |
Antarc* Antarctic Antarctica Ross Sea |
genre_facet |
Antarc* Antarctic Antarctica Ross Sea |
op_source |
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12799 |
op_relation |
Molecular Toxicology https://dx.doi.org/10.3390/ijms232112799 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/ijms232112799 |
container_title |
International Journal of Molecular Sciences |
container_volume |
23 |
container_issue |
21 |
container_start_page |
12799 |
_version_ |
1774712337660379136 |