Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices
Skin is being increasingly exposed to artificial blue light due to the extensive use of electronic devices. This, together with recent observations reporting that blue light—also known as high-energy visible light—can exert cytotoxic effects associated with oxidative stress and promote hyperpigmenta...
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ftmdpi:oai:mdpi.com:/1422-0067/21/3/988/ 2023-08-20T04:01:23+02:00 Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices Silvia Lorrio Azahara Rodríguez-Luna Pablo Delgado-Wicke Marta Mascaraque María Gallego Azahara Pérez-Davó Salvador González Ángeles Juarranz agris 2020-02-02 application/pdf https://doi.org/10.3390/ijms21030988 EN eng Multidisciplinary Digital Publishing Institute Biochemistry https://dx.doi.org/10.3390/ijms21030988 https://creativecommons.org/licenses/by/4.0/ International Journal of Molecular Sciences; Volume 21; Issue 3; Pages: 988 artificial blue light hyperpigmentation reactive oxygen species natural extract dermal fibroblast melanocyte Text 2020 ftmdpi https://doi.org/10.3390/ijms21030988 2023-07-31T23:04:00Z Skin is being increasingly exposed to artificial blue light due to the extensive use of electronic devices. This, together with recent observations reporting that blue light—also known as high-energy visible light—can exert cytotoxic effects associated with oxidative stress and promote hyperpigmentation, has sparked interest in blue light and its potential harmful effects on skin. The photoprotective properties of new extracts of different botanicals with antioxidant activity are therefore being studied. Deschampsia antarctica (Edafence®, EDA), a natural aqueous extract, has shown keratinocyte and fibroblast cell protection effects against ultraviolet radiation and dioxin toxicity. In this regard, we studied the protective capacity of EDA against the deleterious effects of artificial blue light irradiation in human dermal fibroblasts (HDF) and melanocytes. We analyzed the impact of EDA on viability, cell morphology, oxidative stress, melanogenic signaling pathway activation and hyperpigmentation in HDF and melanocytes subjected to artificial blue light irradiation. Our results show that EDA protects against cell damage caused by artificial blue light, decreasing oxidative stress, melanogenic signaling pathway activation and hyperpigmentation caused by blue light irradiation. All these findings suggest that EDA might help prevent skin damage produced by artificial blue light exposure from screen of electronic devices. Text Antarc* Antarctica MDPI Open Access Publishing International Journal of Molecular Sciences 21 3 988 |
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MDPI Open Access Publishing |
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ftmdpi |
language |
English |
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artificial blue light hyperpigmentation reactive oxygen species natural extract dermal fibroblast melanocyte |
spellingShingle |
artificial blue light hyperpigmentation reactive oxygen species natural extract dermal fibroblast melanocyte Silvia Lorrio Azahara Rodríguez-Luna Pablo Delgado-Wicke Marta Mascaraque María Gallego Azahara Pérez-Davó Salvador González Ángeles Juarranz Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices |
topic_facet |
artificial blue light hyperpigmentation reactive oxygen species natural extract dermal fibroblast melanocyte |
description |
Skin is being increasingly exposed to artificial blue light due to the extensive use of electronic devices. This, together with recent observations reporting that blue light—also known as high-energy visible light—can exert cytotoxic effects associated with oxidative stress and promote hyperpigmentation, has sparked interest in blue light and its potential harmful effects on skin. The photoprotective properties of new extracts of different botanicals with antioxidant activity are therefore being studied. Deschampsia antarctica (Edafence®, EDA), a natural aqueous extract, has shown keratinocyte and fibroblast cell protection effects against ultraviolet radiation and dioxin toxicity. In this regard, we studied the protective capacity of EDA against the deleterious effects of artificial blue light irradiation in human dermal fibroblasts (HDF) and melanocytes. We analyzed the impact of EDA on viability, cell morphology, oxidative stress, melanogenic signaling pathway activation and hyperpigmentation in HDF and melanocytes subjected to artificial blue light irradiation. Our results show that EDA protects against cell damage caused by artificial blue light, decreasing oxidative stress, melanogenic signaling pathway activation and hyperpigmentation caused by blue light irradiation. All these findings suggest that EDA might help prevent skin damage produced by artificial blue light exposure from screen of electronic devices. |
format |
Text |
author |
Silvia Lorrio Azahara Rodríguez-Luna Pablo Delgado-Wicke Marta Mascaraque María Gallego Azahara Pérez-Davó Salvador González Ángeles Juarranz |
author_facet |
Silvia Lorrio Azahara Rodríguez-Luna Pablo Delgado-Wicke Marta Mascaraque María Gallego Azahara Pérez-Davó Salvador González Ángeles Juarranz |
author_sort |
Silvia Lorrio |
title |
Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices |
title_short |
Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices |
title_full |
Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices |
title_fullStr |
Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices |
title_full_unstemmed |
Protective Effect of the Aqueous Extract of Deschampsia antarctica (EDAFENCE®) on Skin Cells against Blue Light Emitted from Digital Devices |
title_sort |
protective effect of the aqueous extract of deschampsia antarctica (edafence®) on skin cells against blue light emitted from digital devices |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2020 |
url |
https://doi.org/10.3390/ijms21030988 |
op_coverage |
agris |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
International Journal of Molecular Sciences; Volume 21; Issue 3; Pages: 988 |
op_relation |
Biochemistry https://dx.doi.org/10.3390/ijms21030988 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/ijms21030988 |
container_title |
International Journal of Molecular Sciences |
container_volume |
21 |
container_issue |
3 |
container_start_page |
988 |
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1774724664975687680 |