Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa)
Atlantic sea cucumber is a benthic marine echinoderm found in Northwest Atlantic waters and is harvested mainly for its body wall. The body wall, along with internal organs and aquaphyrangeal bulb/flower, is a rich source of proteins, where the latter parts are often considered as processing discard...
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ftmdpi:oai:mdpi.com:/1420-3049/28/13/5263/ 2023-08-20T04:06:06+02:00 Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) Tharindu R. L. Senadheera Abul Hossain Deepika Dave Fereidoon Shahidi agris 2023-07-07 application/pdf https://doi.org/10.3390/molecules28135263 EN eng Multidisciplinary Digital Publishing Institute https://dx.doi.org/10.3390/molecules28135263 https://creativecommons.org/licenses/by/4.0/ Molecules; Volume 28; Issue 13; Pages: 5263 sea cucumber protein hydrolysate antioxidant activity ACE inhibition LDL cholesterol oxidation DNA scission inhibition Text 2023 ftmdpi https://doi.org/10.3390/molecules28135263 2023-08-01T10:46:42Z Atlantic sea cucumber is a benthic marine echinoderm found in Northwest Atlantic waters and is harvested mainly for its body wall. The body wall, along with internal organs and aquaphyrangeal bulb/flower, is a rich source of proteins, where the latter parts are often considered as processing discards. The objective of this research was to produce protein hydrolysates from sea cucumber tissues (body wall, flower, and internal organs) with bioactive properties associated with antioxidants, DNA and LDL cholesterol oxidation inhibition, and angiotensin-I-converting enzyme (ACE) inhibitory effects. The protein hydrolysates were prepared using food-grade commercial enzymes, namely Alcalase, Corolase, and Flavourzyme, individually and in combination, and found that the combination of enzymes exhibited stronger antioxidant potential than the individual enzymes, as well as their untreated counterparts. Similar trends were also observed for the DNA and LDL cholesterol oxidation inhibition and ACE-inhibitory properties of sea cucumber protein hydrolysates, mainly those that were prepared from the flower. Thus, the findings of this study revealed potential applications of sea cucumber-derived protein hydrolysates in functional foods, nutraceuticals, and dietary supplements, as well as natural therapeutics. Text Cucumaria frondosa Northwest Atlantic MDPI Open Access Publishing Molecules 28 13 5263 |
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MDPI Open Access Publishing |
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sea cucumber protein hydrolysate antioxidant activity ACE inhibition LDL cholesterol oxidation DNA scission inhibition |
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sea cucumber protein hydrolysate antioxidant activity ACE inhibition LDL cholesterol oxidation DNA scission inhibition Tharindu R. L. Senadheera Abul Hossain Deepika Dave Fereidoon Shahidi Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) |
topic_facet |
sea cucumber protein hydrolysate antioxidant activity ACE inhibition LDL cholesterol oxidation DNA scission inhibition |
description |
Atlantic sea cucumber is a benthic marine echinoderm found in Northwest Atlantic waters and is harvested mainly for its body wall. The body wall, along with internal organs and aquaphyrangeal bulb/flower, is a rich source of proteins, where the latter parts are often considered as processing discards. The objective of this research was to produce protein hydrolysates from sea cucumber tissues (body wall, flower, and internal organs) with bioactive properties associated with antioxidants, DNA and LDL cholesterol oxidation inhibition, and angiotensin-I-converting enzyme (ACE) inhibitory effects. The protein hydrolysates were prepared using food-grade commercial enzymes, namely Alcalase, Corolase, and Flavourzyme, individually and in combination, and found that the combination of enzymes exhibited stronger antioxidant potential than the individual enzymes, as well as their untreated counterparts. Similar trends were also observed for the DNA and LDL cholesterol oxidation inhibition and ACE-inhibitory properties of sea cucumber protein hydrolysates, mainly those that were prepared from the flower. Thus, the findings of this study revealed potential applications of sea cucumber-derived protein hydrolysates in functional foods, nutraceuticals, and dietary supplements, as well as natural therapeutics. |
format |
Text |
author |
Tharindu R. L. Senadheera Abul Hossain Deepika Dave Fereidoon Shahidi |
author_facet |
Tharindu R. L. Senadheera Abul Hossain Deepika Dave Fereidoon Shahidi |
author_sort |
Tharindu R. L. Senadheera |
title |
Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) |
title_short |
Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) |
title_full |
Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) |
title_fullStr |
Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) |
title_full_unstemmed |
Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Cucumaria frondosa) |
title_sort |
antioxidant and ace-inhibitory activity of protein hydrolysates produced from atlantic sea cucumber (cucumaria frondosa) |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2023 |
url |
https://doi.org/10.3390/molecules28135263 |
op_coverage |
agris |
genre |
Cucumaria frondosa Northwest Atlantic |
genre_facet |
Cucumaria frondosa Northwest Atlantic |
op_source |
Molecules; Volume 28; Issue 13; Pages: 5263 |
op_relation |
https://dx.doi.org/10.3390/molecules28135263 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/molecules28135263 |
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Molecules |
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28 |
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13 |
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5263 |
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1774717021416587264 |