On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions
Microwave energy (MWe) is, nowadays, widely used as a clean synthesis tool to improve several chemical reactions, such as drug molecule synthesis, carbohydrate conversion and biomass pyrolysis. On the other hand, its exploitation in enzymatic reactions has only been fleetingly investigated and, henc...
Published in: | Molecules |
---|---|
Main Authors: | , , |
Format: | Text |
Language: | English |
Published: |
Multidisciplinary Digital Publishing Institute
2016
|
Subjects: | |
Online Access: | https://doi.org/10.3390/molecules21091245 |
id |
ftmdpi:oai:mdpi.com:/1420-3049/21/9/1245/ |
---|---|
record_format |
openpolar |
spelling |
ftmdpi:oai:mdpi.com:/1420-3049/21/9/1245/ 2023-08-20T04:00:02+02:00 On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions Alessandro Pellis Georg Guebitz Thomas Farmer agris 2016-09-19 application/pdf https://doi.org/10.3390/molecules21091245 EN eng Multidisciplinary Digital Publishing Institute Green Chemistry https://dx.doi.org/10.3390/molecules21091245 https://creativecommons.org/licenses/by/4.0/ Molecules; Volume 21; Issue 9; Pages: 1245 Candida antarctica lipase B microwave energy polycondensation reactions enzymatic synthesis bio-based monomers bio-based polymers platform molecules Text 2016 ftmdpi https://doi.org/10.3390/molecules21091245 2023-07-31T20:57:15Z Microwave energy (MWe) is, nowadays, widely used as a clean synthesis tool to improve several chemical reactions, such as drug molecule synthesis, carbohydrate conversion and biomass pyrolysis. On the other hand, its exploitation in enzymatic reactions has only been fleetingly investigated and, hence, further study of MWe is required to reach a precise understanding of its potential in this field. Starting from the authors’ experience in clean synthesis and biocatalyzed reactions, this study sheds light on the possibility of using MWe for enhancing enzyme-catalyzed polycondensation reactions and pre-polymer formation. Several systems and set ups were investigated involving bulk and organic media (solution phase) reactions, different enzymatic preparations and various starting bio-based monomers. Results show that MWe enables the biocatalyzed synthesis of polyesters and pre-polymers in a similar way to that reported using conventional heating with an oil bath, but in a few cases, notably bulk phase polycondensations under intense microwave irradiation, MWe leads to a rapid enzyme deactivation. Text Antarc* Antarctica MDPI Open Access Publishing Molecules 21 9 1245 |
institution |
Open Polar |
collection |
MDPI Open Access Publishing |
op_collection_id |
ftmdpi |
language |
English |
topic |
Candida antarctica lipase B microwave energy polycondensation reactions enzymatic synthesis bio-based monomers bio-based polymers platform molecules |
spellingShingle |
Candida antarctica lipase B microwave energy polycondensation reactions enzymatic synthesis bio-based monomers bio-based polymers platform molecules Alessandro Pellis Georg Guebitz Thomas Farmer On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions |
topic_facet |
Candida antarctica lipase B microwave energy polycondensation reactions enzymatic synthesis bio-based monomers bio-based polymers platform molecules |
description |
Microwave energy (MWe) is, nowadays, widely used as a clean synthesis tool to improve several chemical reactions, such as drug molecule synthesis, carbohydrate conversion and biomass pyrolysis. On the other hand, its exploitation in enzymatic reactions has only been fleetingly investigated and, hence, further study of MWe is required to reach a precise understanding of its potential in this field. Starting from the authors’ experience in clean synthesis and biocatalyzed reactions, this study sheds light on the possibility of using MWe for enhancing enzyme-catalyzed polycondensation reactions and pre-polymer formation. Several systems and set ups were investigated involving bulk and organic media (solution phase) reactions, different enzymatic preparations and various starting bio-based monomers. Results show that MWe enables the biocatalyzed synthesis of polyesters and pre-polymers in a similar way to that reported using conventional heating with an oil bath, but in a few cases, notably bulk phase polycondensations under intense microwave irradiation, MWe leads to a rapid enzyme deactivation. |
format |
Text |
author |
Alessandro Pellis Georg Guebitz Thomas Farmer |
author_facet |
Alessandro Pellis Georg Guebitz Thomas Farmer |
author_sort |
Alessandro Pellis |
title |
On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions |
title_short |
On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions |
title_full |
On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions |
title_fullStr |
On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions |
title_full_unstemmed |
On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions |
title_sort |
on the effect of microwave energy on lipase-catalyzed polycondensation reactions |
publisher |
Multidisciplinary Digital Publishing Institute |
publishDate |
2016 |
url |
https://doi.org/10.3390/molecules21091245 |
op_coverage |
agris |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_source |
Molecules; Volume 21; Issue 9; Pages: 1245 |
op_relation |
Green Chemistry https://dx.doi.org/10.3390/molecules21091245 |
op_rights |
https://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.3390/molecules21091245 |
container_title |
Molecules |
container_volume |
21 |
container_issue |
9 |
container_start_page |
1245 |
_version_ |
1774716494662336512 |