The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors
Lonicera caerulea is a species of bush native to the Kamchatka Peninsula (Russian Far East) whose berries have been extensively studied due to their potential high antioxidant activity. The aim of our work was to investigate the in vivo effects of the antioxidant action of Lonicera caerulea berry ex...
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Molecular Diversity Preservation International
2008
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ftmdpi:oai:mdpi.com:/1420-3049/13/5/1195/ 2023-08-20T04:07:40+02:00 The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors Maria Iuliana Gruia Eliza Oprea Ion Gruia Valentina Negoita Ileana Cornelia Farcasanu agris 2008-05-27 application/pdf https://doi.org/10.3390/molecules13051195 EN eng Molecular Diversity Preservation International https://dx.doi.org/10.3390/molecules13051195 https://creativecommons.org/licenses/by/3.0/ Molecules; Volume 13; Issue 5; Pages: 1195-1206 Antioxidant Lonicera caerulaea experimental tumors lipid peroxidation ceruloplasmin thiol groups Text 2008 ftmdpi https://doi.org/10.3390/molecules13051195 2023-07-31T20:21:42Z Lonicera caerulea is a species of bush native to the Kamchatka Peninsula (Russian Far East) whose berries have been extensively studied due to their potential high antioxidant activity. The aim of our work was to investigate the in vivo effects of the antioxidant action of Lonicera caerulea berry extracts on the dynamics of experimentallyinduced tumors. Our data showed that aqueous Lonicera caerulaea extracts reduced the tumor volume when administered continuously during the tumor growth and development stages, but augmented the tumor growth when the administration of extracts started three weeks before tumor grafting. Prolonged administration of Lonicera caerulaea berry extracts induced the antioxidant defense mechanism in the tumor tissues, while surprisingly amplifying the peripheral oxidative stress. Text Kamchatka Kamchatka Peninsula MDPI Open Access Publishing Kamchatka Peninsula ENVELOPE(160.000,160.000,56.000,56.000) Molecules 13 5 1195 1206 |
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MDPI Open Access Publishing |
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English |
topic |
Antioxidant Lonicera caerulaea experimental tumors lipid peroxidation ceruloplasmin thiol groups |
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Antioxidant Lonicera caerulaea experimental tumors lipid peroxidation ceruloplasmin thiol groups Maria Iuliana Gruia Eliza Oprea Ion Gruia Valentina Negoita Ileana Cornelia Farcasanu The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors |
topic_facet |
Antioxidant Lonicera caerulaea experimental tumors lipid peroxidation ceruloplasmin thiol groups |
description |
Lonicera caerulea is a species of bush native to the Kamchatka Peninsula (Russian Far East) whose berries have been extensively studied due to their potential high antioxidant activity. The aim of our work was to investigate the in vivo effects of the antioxidant action of Lonicera caerulea berry extracts on the dynamics of experimentallyinduced tumors. Our data showed that aqueous Lonicera caerulaea extracts reduced the tumor volume when administered continuously during the tumor growth and development stages, but augmented the tumor growth when the administration of extracts started three weeks before tumor grafting. Prolonged administration of Lonicera caerulaea berry extracts induced the antioxidant defense mechanism in the tumor tissues, while surprisingly amplifying the peripheral oxidative stress. |
format |
Text |
author |
Maria Iuliana Gruia Eliza Oprea Ion Gruia Valentina Negoita Ileana Cornelia Farcasanu |
author_facet |
Maria Iuliana Gruia Eliza Oprea Ion Gruia Valentina Negoita Ileana Cornelia Farcasanu |
author_sort |
Maria Iuliana Gruia |
title |
The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors |
title_short |
The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors |
title_full |
The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors |
title_fullStr |
The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors |
title_full_unstemmed |
The Antioxidant Response Induced by Lonicera caerulaea Berry Extracts in Animals Bearing Experimental Solid Tumors |
title_sort |
antioxidant response induced by lonicera caerulaea berry extracts in animals bearing experimental solid tumors |
publisher |
Molecular Diversity Preservation International |
publishDate |
2008 |
url |
https://doi.org/10.3390/molecules13051195 |
op_coverage |
agris |
long_lat |
ENVELOPE(160.000,160.000,56.000,56.000) |
geographic |
Kamchatka Peninsula |
geographic_facet |
Kamchatka Peninsula |
genre |
Kamchatka Kamchatka Peninsula |
genre_facet |
Kamchatka Kamchatka Peninsula |
op_source |
Molecules; Volume 13; Issue 5; Pages: 1195-1206 |
op_relation |
https://dx.doi.org/10.3390/molecules13051195 |
op_rights |
https://creativecommons.org/licenses/by/3.0/ |
op_doi |
https://doi.org/10.3390/molecules13051195 |
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Molecules |
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13 |
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5 |
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1195 |
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1206 |
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1774719468986957824 |