RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome
The Greenland shark (Somniosus microcephalus) is an enigmatic species known for its exceptional longevity and extraordinary adaptations to the cold environment. This animal lives in the arctic and subarctic regions of the North Atlantic Ocean. Surprisingly, even though it is a vertebrate with the lo...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Masaryk Univerzity
2024
|
Subjects: | |
Online Access: | https://journals.muni.cz/CPR/article/view/38141 |
id |
ftmasarykunivojs:oai:ojs.journals.muni.cz:article/38141 |
---|---|
record_format |
openpolar |
spelling |
ftmasarykunivojs:oai:ojs.journals.muni.cz:article/38141 2024-04-14T08:07:54+00:00 RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav 2024-03-15 application/pdf application/zip https://journals.muni.cz/CPR/article/view/38141 eng eng Masaryk Univerzity https://journals.muni.cz/CPR/article/view/38141/32439 https://journals.muni.cz/CPR/article/view/38141/32440 https://journals.muni.cz/CPR/article/view/38141 Copyright © 2024 Martin Bartas, Jiří Červeň, Natália Valková, Adriana Volná, Michaela Dobrovolná, Lucie Šislerová, Hörður Baldvinsson, Petr Pečinka, Václav Brázda Czech Polar Reports; Vol 13 No 2 (2023); 210–227 Czech Polar Reports; Vol. 13 No. 2 (2023); 210–227 1805-0697 1805-0689 Greenland shark transcriptome bioinformatics LINE-1 longevity research Somniosus microcephalus info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2024 ftmasarykunivojs 2024-03-21T15:48:35Z The Greenland shark (Somniosus microcephalus) is an enigmatic species known for its exceptional longevity and extraordinary adaptations to the cold environment. This animal lives in the arctic and subarctic regions of the North Atlantic Ocean. Surprisingly, even though it is a vertebrate with the longest known lifespan, its transcriptome has not been studied yet. Therefore, we isolated and analyzed RNA in the Greenland shark samples. Our findings reveal some important information about the possible genetic mechanisms that could contribute to its longevity. We identified a highly expressed long interspersed nuclear element-like transcript (LINE-like) that is supposed to be associated with extended lifespan and resilience to age-related diseases, possibly through an improved telomere maintenance mechanism. This research not only contributes to our understanding of the biology and evolution of the Greenland shark but could also have implications for human longevity research. Article in Journal/Newspaper Arctic Greenland North Atlantic Somniosus microcephalus Subarctic Masaryk University Journals Arctic Greenland |
institution |
Open Polar |
collection |
Masaryk University Journals |
op_collection_id |
ftmasarykunivojs |
language |
English |
topic |
Greenland shark transcriptome bioinformatics LINE-1 longevity research Somniosus microcephalus |
spellingShingle |
Greenland shark transcriptome bioinformatics LINE-1 longevity research Somniosus microcephalus Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
topic_facet |
Greenland shark transcriptome bioinformatics LINE-1 longevity research Somniosus microcephalus |
description |
The Greenland shark (Somniosus microcephalus) is an enigmatic species known for its exceptional longevity and extraordinary adaptations to the cold environment. This animal lives in the arctic and subarctic regions of the North Atlantic Ocean. Surprisingly, even though it is a vertebrate with the longest known lifespan, its transcriptome has not been studied yet. Therefore, we isolated and analyzed RNA in the Greenland shark samples. Our findings reveal some important information about the possible genetic mechanisms that could contribute to its longevity. We identified a highly expressed long interspersed nuclear element-like transcript (LINE-like) that is supposed to be associated with extended lifespan and resilience to age-related diseases, possibly through an improved telomere maintenance mechanism. This research not only contributes to our understanding of the biology and evolution of the Greenland shark but could also have implications for human longevity research. |
format |
Article in Journal/Newspaper |
author |
Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav |
author_facet |
Bartas, Martin Červeň, Jiří Valková, Natália Volná, Adriana Dobrovolná, Michaela Šislerová, Lucie Baldvinsson, Hörður Pečinka, Petr Brázda, Václav |
author_sort |
Bartas, Martin |
title |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_short |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_full |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_fullStr |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_full_unstemmed |
RNA analysis of the longest living vertebrate Greenland shark revealed an abundance of LINE-like elements in its transcriptome |
title_sort |
rna analysis of the longest living vertebrate greenland shark revealed an abundance of line-like elements in its transcriptome |
publisher |
Masaryk Univerzity |
publishDate |
2024 |
url |
https://journals.muni.cz/CPR/article/view/38141 |
geographic |
Arctic Greenland |
geographic_facet |
Arctic Greenland |
genre |
Arctic Greenland North Atlantic Somniosus microcephalus Subarctic |
genre_facet |
Arctic Greenland North Atlantic Somniosus microcephalus Subarctic |
op_source |
Czech Polar Reports; Vol 13 No 2 (2023); 210–227 Czech Polar Reports; Vol. 13 No. 2 (2023); 210–227 1805-0697 1805-0689 |
op_relation |
https://journals.muni.cz/CPR/article/view/38141/32439 https://journals.muni.cz/CPR/article/view/38141/32440 https://journals.muni.cz/CPR/article/view/38141 |
op_rights |
Copyright © 2024 Martin Bartas, Jiří Červeň, Natália Valková, Adriana Volná, Michaela Dobrovolná, Lucie Šislerová, Hörður Baldvinsson, Petr Pečinka, Václav Brázda |
_version_ |
1796305308222488576 |