Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes?
Recent studies of fish red blood cells found that a regular paracrystalline array of hemoglobin (Hb) tetamers formed under low oxygen conditions in 2 species of boreal fishes, Atlantic cod (Gadus morhua) and toadfish, (Opsanus tau). This phenomenon is termed hemoglobin gelation and its physiological...
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ftmaineuniv:oai:digitalcommons.library.umaine.edu:orsp_reports-1193 2023-05-15T15:02:18+02:00 Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? Hunt Von Herbing, Ione 2003-02-21T08:00:00Z application/pdf https://digitalcommons.library.umaine.edu/orsp_reports/187 https://digitalcommons.library.umaine.edu/cgi/viewcontent.cgi?article=1193&context=orsp_reports unknown DigitalCommons@UMaine https://digitalcommons.library.umaine.edu/orsp_reports/187 https://digitalcommons.library.umaine.edu/cgi/viewcontent.cgi?article=1193&context=orsp_reports This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. In addition, no permission is required from the rights-holder(s) for educational uses. For other uses, you need to obtain permission from the rights-holder(s). University of Maine Office of Research Administration: Grant Reports Hemoglobin tetamers Atlantic cod Toadfish Cellular and Molecular Physiology Marine Biology text 2003 ftmaineuniv 2023-03-12T19:15:56Z Recent studies of fish red blood cells found that a regular paracrystalline array of hemoglobin (Hb) tetamers formed under low oxygen conditions in 2 species of boreal fishes, Atlantic cod (Gadus morhua) and toadfish, (Opsanus tau). This phenomenon is termed hemoglobin gelation and its physiological characteristics and importance to survival of boreal fishes is unknown. The study outlined in this proposal will obtain preliminary data on the frequency and physiological nature of the phenomenon of hemoglobin (Hb) gelation in red blood cells of fishes that inhabit cold-water temperate and Arctic environments. The present study will test the hypothesis that hemoglobin gelation within fish red blood cells may be a feature of normal fish respiratory physiology and might be adaptive in extreme cold-water environments. Twelve fish species have been examined to date, and only the cold-water boreal marine fishes exhibited Hb gelation. In one species, Atlantic cod, gelation was relatively mild and did not result in changes in the gross morphology of the blood cells. In a second species, toadfish, gelation resulted in large crystalline structures that disrupted the red cell membranes and ruptured blood cells. The differences in type and severity of Hb gelation among fish species may directly affect their physiology and ultimately play an important part in their capacity for survival. However, too few species have been assayed to determine the extent of hemoglobin gelation in boreal fishes and no data exists on the physiological conditions that facilitate gelation. Few experimental links have been established between gelation and fish hemoglobin structure or between the variation in hemoglobin type and physiology.In this study blood will be sampled from a large number of boreal and Arctic fishes and tested for Hb gelation and the presence of the Hb paracrystalline matrix. These data will provide an accurate assessment of the distribution of the gelation phenomenon within boreal fishes and any correlation with genetic ... Text Arctic atlantic cod Gadus morhua The University of Maine: DigitalCommons@UMaine Arctic |
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The University of Maine: DigitalCommons@UMaine |
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Hemoglobin tetamers Atlantic cod Toadfish Cellular and Molecular Physiology Marine Biology |
spellingShingle |
Hemoglobin tetamers Atlantic cod Toadfish Cellular and Molecular Physiology Marine Biology Hunt Von Herbing, Ione Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? |
topic_facet |
Hemoglobin tetamers Atlantic cod Toadfish Cellular and Molecular Physiology Marine Biology |
description |
Recent studies of fish red blood cells found that a regular paracrystalline array of hemoglobin (Hb) tetamers formed under low oxygen conditions in 2 species of boreal fishes, Atlantic cod (Gadus morhua) and toadfish, (Opsanus tau). This phenomenon is termed hemoglobin gelation and its physiological characteristics and importance to survival of boreal fishes is unknown. The study outlined in this proposal will obtain preliminary data on the frequency and physiological nature of the phenomenon of hemoglobin (Hb) gelation in red blood cells of fishes that inhabit cold-water temperate and Arctic environments. The present study will test the hypothesis that hemoglobin gelation within fish red blood cells may be a feature of normal fish respiratory physiology and might be adaptive in extreme cold-water environments. Twelve fish species have been examined to date, and only the cold-water boreal marine fishes exhibited Hb gelation. In one species, Atlantic cod, gelation was relatively mild and did not result in changes in the gross morphology of the blood cells. In a second species, toadfish, gelation resulted in large crystalline structures that disrupted the red cell membranes and ruptured blood cells. The differences in type and severity of Hb gelation among fish species may directly affect their physiology and ultimately play an important part in their capacity for survival. However, too few species have been assayed to determine the extent of hemoglobin gelation in boreal fishes and no data exists on the physiological conditions that facilitate gelation. Few experimental links have been established between gelation and fish hemoglobin structure or between the variation in hemoglobin type and physiology.In this study blood will be sampled from a large number of boreal and Arctic fishes and tested for Hb gelation and the presence of the Hb paracrystalline matrix. These data will provide an accurate assessment of the distribution of the gelation phenomenon within boreal fishes and any correlation with genetic ... |
format |
Text |
author |
Hunt Von Herbing, Ione |
author_facet |
Hunt Von Herbing, Ione |
author_sort |
Hunt Von Herbing, Ione |
title |
Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? |
title_short |
Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? |
title_full |
Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? |
title_fullStr |
Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? |
title_full_unstemmed |
Is Hemoglobin Gelation an Adaptation to the Cold in Boreal Fishes? |
title_sort |
is hemoglobin gelation an adaptation to the cold in boreal fishes? |
publisher |
DigitalCommons@UMaine |
publishDate |
2003 |
url |
https://digitalcommons.library.umaine.edu/orsp_reports/187 https://digitalcommons.library.umaine.edu/cgi/viewcontent.cgi?article=1193&context=orsp_reports |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic atlantic cod Gadus morhua |
genre_facet |
Arctic atlantic cod Gadus morhua |
op_source |
University of Maine Office of Research Administration: Grant Reports |
op_relation |
https://digitalcommons.library.umaine.edu/orsp_reports/187 https://digitalcommons.library.umaine.edu/cgi/viewcontent.cgi?article=1193&context=orsp_reports |
op_rights |
This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. In addition, no permission is required from the rights-holder(s) for educational uses. For other uses, you need to obtain permission from the rights-holder(s). |
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1766334275670507520 |