Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management.
Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we invest...
Published in: | International Journal of Chronic Obstructive Pulmonary Disease |
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Informa UK Limited
2021
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Online Access: | https://researchonline.lshtm.ac.uk/id/eprint/4660886/ https://researchonline.lshtm.ac.uk/id/eprint/4660886/1/COPD-292472-chronic-obstructive-pulmonary-disease--copd--in-population-s.pdf |
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ftlshtm:oai:researchonline.lshtm.ac.uk:4660886 2023-05-15T18:34:17+02:00 Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. Cook, Sarah Eggen, Anne Elise Hopstock, Laila A Malyutina, Sofia Shapkina, Marina Kudryavtsev, Alexander V Melbye, Hasse Quint, Jennifer K 2021-05-14 text https://researchonline.lshtm.ac.uk/id/eprint/4660886/ https://researchonline.lshtm.ac.uk/id/eprint/4660886/1/COPD-292472-chronic-obstructive-pulmonary-disease--copd--in-population-s.pdf en eng Informa UK Limited https://researchonline.lshtm.ac.uk/id/eprint/4660886/1/COPD-292472-chronic-obstructive-pulmonary-disease--copd--in-population-s.pdf Cook, Sarah <https://researchonline.lshtm.ac.uk/view/creators/ppehscoo.html>; Eggen, Anne Elise; Hopstock, Laila A; Malyutina, Sofia; Shapkina, Marina; Kudryavtsev, Alexander V; Melbye, Hasse; Quint, Jennifer K; (2021) Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. International Journal of Chronic Obstructive Pulmonary Disease, 16. pp. 1353-1368. DOI: https://doi.org/10.2147/COPD.S292472 <https://doi.org/10.2147/COPD.S292472> cc_by_nc_nd CC-BY-NC-ND Article NonPeerReviewed 2021 ftlshtm https://doi.org/10.2147/COPD.S292472 2022-03-03T07:34:32Z Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we investigated the prevalence of both obstructive lung disease and respiratory symptoms in a population-based study conducted in two Russian cities and compared the findings with a similar study from Norway conducted in the same time period. Methods: The study population was a sub-sample of participants aged 40-69 years participating in the Know Your Heart (KYH) study in Russia in 2015-18 (n=1883) and in the 7th survey of the Tromsø Study (n=5271) carried out in Norway in 2015-16 (Tromsø 7) who participated in spirometry examinations. The main outcome was obstructive lung function (FEV1/FVC ratio< lower limit of normal on pre-bronchodilator spirometry examination) with and without respiratory symptoms (chronic cough and breathlessness). In those with obstructive lung function, awareness (known diagnosis) and management (use of medications, smoking cessation) were compared. Results: The age-standardized prevalence of obstructive lung function was similar among men in both studies (KYH 11.0% vs Tromsø 7 9.8%, p=0.21) and higher in the Norwegian (9.4%) than Russian (6.8%) women (p=0.006). In contrast, the prevalence of obstructive lung function plus respiratory symptoms was higher in Russian men (KYH 8.3% vs Tromsø 7 4.7%, p<0.001) but similar in women (KYH 5.9% vs Tromsø 7 6.4%, p=0.18). There was a much higher prevalence of respiratory symptoms in Russian than Norwegian participants of both sexes regardless of presence of obstructive lung function. Conclusion: The prevalence of respiratory symptoms was strikingly high among Russian participants but this was not explained by a higher burden of obstructive lung function on spirometry testing in comparison with Norwegian participants. Further work is needed to understand the reasons and health implications of this high prevalence of cough and breathlessness. Article in Journal/Newspaper Tromsø London School of Hygiene & Tropical Medicine: LSHTM Research Online Norway Tromsø International Journal of Chronic Obstructive Pulmonary Disease Volume 16 1353 1368 |
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London School of Hygiene & Tropical Medicine: LSHTM Research Online |
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English |
description |
Background: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Despite a high prevalence of smoking and respiratory symptoms, two recent population-based studies in Russia found a relatively low prevalence of obstructive lung function. Here, we investigated the prevalence of both obstructive lung disease and respiratory symptoms in a population-based study conducted in two Russian cities and compared the findings with a similar study from Norway conducted in the same time period. Methods: The study population was a sub-sample of participants aged 40-69 years participating in the Know Your Heart (KYH) study in Russia in 2015-18 (n=1883) and in the 7th survey of the Tromsø Study (n=5271) carried out in Norway in 2015-16 (Tromsø 7) who participated in spirometry examinations. The main outcome was obstructive lung function (FEV1/FVC ratio< lower limit of normal on pre-bronchodilator spirometry examination) with and without respiratory symptoms (chronic cough and breathlessness). In those with obstructive lung function, awareness (known diagnosis) and management (use of medications, smoking cessation) were compared. Results: The age-standardized prevalence of obstructive lung function was similar among men in both studies (KYH 11.0% vs Tromsø 7 9.8%, p=0.21) and higher in the Norwegian (9.4%) than Russian (6.8%) women (p=0.006). In contrast, the prevalence of obstructive lung function plus respiratory symptoms was higher in Russian men (KYH 8.3% vs Tromsø 7 4.7%, p<0.001) but similar in women (KYH 5.9% vs Tromsø 7 6.4%, p=0.18). There was a much higher prevalence of respiratory symptoms in Russian than Norwegian participants of both sexes regardless of presence of obstructive lung function. Conclusion: The prevalence of respiratory symptoms was strikingly high among Russian participants but this was not explained by a higher burden of obstructive lung function on spirometry testing in comparison with Norwegian participants. Further work is needed to understand the reasons and health implications of this high prevalence of cough and breathlessness. |
format |
Article in Journal/Newspaper |
author |
Cook, Sarah Eggen, Anne Elise Hopstock, Laila A Malyutina, Sofia Shapkina, Marina Kudryavtsev, Alexander V Melbye, Hasse Quint, Jennifer K |
spellingShingle |
Cook, Sarah Eggen, Anne Elise Hopstock, Laila A Malyutina, Sofia Shapkina, Marina Kudryavtsev, Alexander V Melbye, Hasse Quint, Jennifer K Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. |
author_facet |
Cook, Sarah Eggen, Anne Elise Hopstock, Laila A Malyutina, Sofia Shapkina, Marina Kudryavtsev, Alexander V Melbye, Hasse Quint, Jennifer K |
author_sort |
Cook, Sarah |
title |
Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. |
title_short |
Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. |
title_full |
Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. |
title_fullStr |
Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. |
title_full_unstemmed |
Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. |
title_sort |
chronic obstructive pulmonary disease (copd) in population studies in russia and norway: comparison of prevalence, awareness and management. |
publisher |
Informa UK Limited |
publishDate |
2021 |
url |
https://researchonline.lshtm.ac.uk/id/eprint/4660886/ https://researchonline.lshtm.ac.uk/id/eprint/4660886/1/COPD-292472-chronic-obstructive-pulmonary-disease--copd--in-population-s.pdf |
geographic |
Norway Tromsø |
geographic_facet |
Norway Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_relation |
https://researchonline.lshtm.ac.uk/id/eprint/4660886/1/COPD-292472-chronic-obstructive-pulmonary-disease--copd--in-population-s.pdf Cook, Sarah <https://researchonline.lshtm.ac.uk/view/creators/ppehscoo.html>; Eggen, Anne Elise; Hopstock, Laila A; Malyutina, Sofia; Shapkina, Marina; Kudryavtsev, Alexander V; Melbye, Hasse; Quint, Jennifer K; (2021) Chronic Obstructive Pulmonary Disease (COPD) in Population Studies in Russia and Norway: Comparison of Prevalence, Awareness and Management. International Journal of Chronic Obstructive Pulmonary Disease, 16. pp. 1353-1368. DOI: https://doi.org/10.2147/COPD.S292472 <https://doi.org/10.2147/COPD.S292472> |
op_rights |
cc_by_nc_nd |
op_rightsnorm |
CC-BY-NC-ND |
op_doi |
https://doi.org/10.2147/COPD.S292472 |
container_title |
International Journal of Chronic Obstructive Pulmonary Disease |
container_volume |
Volume 16 |
container_start_page |
1353 |
op_container_end_page |
1368 |
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1766218961646518272 |