The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration.
Diphtheria is an acute toxin-mediated superficial infection of the respiratory tract or skin caused by the aerobic gram-positive bacillus Corynebacterium diphtheriae. The epidemiology of infection and clinical manifestations of the disease vary in different parts of the world. Historical accounts of...
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Online Access: | https://researchonline.lshtm.ac.uk/id/eprint/3350117/ |
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ftlshtm:oai:researchonline.lshtm.ac.uk:3350117 2023-05-15T17:24:00+02:00 The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. Aboul-Enein, Basil H Puddy, William C Bowser, Jacquelyn E 2016-12-29 https://researchonline.lshtm.ac.uk/id/eprint/3350117/ unknown Springer (part of Springer Nature) Aboul-Enein, Basil H <https://researchonline.lshtm.ac.uk/view/creators/sdblbabo.html>; Puddy, William C; Bowser, Jacquelyn E; (2016) The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. The Journal of medical humanities, 40 (3). pp. 287-296. ISSN 1041-3545 DOI: https://doi.org/10.1007/s10912-016-9428-y <https://doi.org/10.1007/s10912-016-9428-y> Article PeerReviewed 2016 ftlshtm https://doi.org/10.1007/s10912-016-9428-y 2022-03-03T07:13:00Z Diphtheria is an acute toxin-mediated superficial infection of the respiratory tract or skin caused by the aerobic gram-positive bacillus Corynebacterium diphtheriae. The epidemiology of infection and clinical manifestations of the disease vary in different parts of the world. Historical accounts of diphtheria epidemics have been described in many parts of the world since antiquity. Developed in the late 19th century, the diphtheria antitoxin (DAT) played a pivotal role in the history of public health and vaccinology prior to the advent of the diphtheria-tetanus toxoids and acellular pertussis (DTaP) vaccine. One of the most significant demonstrations of the importance of DAT was its use in the 1925 diphtheria epidemic of Nome, Alaska. Coordinated emergency delivery of this life-saving antitoxin by dog-sled relay in the harshest of conditions has left a profound legacy in the annals of vaccinology and public health. Lead dogs Balto and Togo, and the dog-led antitoxin run of 1925 represent a dynamic illustration of the contribution made by non-human species towards mass immunization in the history of vaccinology. This unique example of cooperative interspecies fellowship and collaboration highlights the importance of the human-animal bond in the one-health initiative. Article in Journal/Newspaper Nome Alaska London School of Hygiene & Tropical Medicine: LSHTM Research Online Journal of Medical Humanities 40 3 287 296 |
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London School of Hygiene & Tropical Medicine: LSHTM Research Online |
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Diphtheria is an acute toxin-mediated superficial infection of the respiratory tract or skin caused by the aerobic gram-positive bacillus Corynebacterium diphtheriae. The epidemiology of infection and clinical manifestations of the disease vary in different parts of the world. Historical accounts of diphtheria epidemics have been described in many parts of the world since antiquity. Developed in the late 19th century, the diphtheria antitoxin (DAT) played a pivotal role in the history of public health and vaccinology prior to the advent of the diphtheria-tetanus toxoids and acellular pertussis (DTaP) vaccine. One of the most significant demonstrations of the importance of DAT was its use in the 1925 diphtheria epidemic of Nome, Alaska. Coordinated emergency delivery of this life-saving antitoxin by dog-sled relay in the harshest of conditions has left a profound legacy in the annals of vaccinology and public health. Lead dogs Balto and Togo, and the dog-led antitoxin run of 1925 represent a dynamic illustration of the contribution made by non-human species towards mass immunization in the history of vaccinology. This unique example of cooperative interspecies fellowship and collaboration highlights the importance of the human-animal bond in the one-health initiative. |
format |
Article in Journal/Newspaper |
author |
Aboul-Enein, Basil H Puddy, William C Bowser, Jacquelyn E |
spellingShingle |
Aboul-Enein, Basil H Puddy, William C Bowser, Jacquelyn E The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. |
author_facet |
Aboul-Enein, Basil H Puddy, William C Bowser, Jacquelyn E |
author_sort |
Aboul-Enein, Basil H |
title |
The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. |
title_short |
The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. |
title_full |
The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. |
title_fullStr |
The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. |
title_full_unstemmed |
The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. |
title_sort |
1925 diphtheria antitoxin run to nome - alaska: a public health illustration of human-animal collaboration. |
publisher |
Springer (part of Springer Nature) |
publishDate |
2016 |
url |
https://researchonline.lshtm.ac.uk/id/eprint/3350117/ |
genre |
Nome Alaska |
genre_facet |
Nome Alaska |
op_relation |
Aboul-Enein, Basil H <https://researchonline.lshtm.ac.uk/view/creators/sdblbabo.html>; Puddy, William C; Bowser, Jacquelyn E; (2016) The 1925 Diphtheria Antitoxin Run to Nome - Alaska: A Public Health Illustration of Human-Animal Collaboration. The Journal of medical humanities, 40 (3). pp. 287-296. ISSN 1041-3545 DOI: https://doi.org/10.1007/s10912-016-9428-y <https://doi.org/10.1007/s10912-016-9428-y> |
op_doi |
https://doi.org/10.1007/s10912-016-9428-y |
container_title |
Journal of Medical Humanities |
container_volume |
40 |
container_issue |
3 |
container_start_page |
287 |
op_container_end_page |
296 |
_version_ |
1766114776123965440 |