Electrochemical device for the rapid detection of genotoxic compounds in fish bile samples
The scientific goal of the present work is the development of a new molecular biomarker as a biomonitoring tool for early assessment of the biological effect of complex mixtures of pollutants (especially polycyclic aromatic hydrocarbons) and validation of the approach by comparison with standard met...
Published in: | Analytical Letters |
---|---|
Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2005
|
Subjects: | |
Online Access: | http://lmavb.lvb.lt/LMAVB:ELABAPDB5611057&prefLang=en_US |
Summary: | The scientific goal of the present work is the development of a new molecular biomarker as a biomonitoring tool for early assessment of the biological effect of complex mixtures of pollutants (especially polycyclic aromatic hydrocarbons) and validation of the approach by comparison with standard methodologies. Hence, a DNA-based biosensor, which is able to detect the presence of compounds with affinity for DNA to measure their effect on the guanine base, was used in this research. |
---|