Electrochemical device for the rapid detection of genotoxic compounds in fish bile samples

The scientific goal of the present work is the development of a new molecular biomarker as a biomonitoring tool for early assessment of the biological effect of complex mixtures of pollutants (especially polycyclic aromatic hydrocarbons) and validation of the approach by comparison with standard met...

Full description

Bibliographic Details
Published in:Analytical Letters
Main Authors: Bagni, Graziana, Baussant, Thierry, Jonsson, Grete, Baršienė, Janina, Mascini, Marco
Format: Article in Journal/Newspaper
Language:English
Published: 2005
Subjects:
Polycyclic aromatic-hydrocarbons
Fixed-wavelength fluorescence
Atlantic cod
Dna biosensor
Pah
Metabolites
Exposure
atlantic cod
Online Access:http://lmavb.lvb.lt/LMAVB:ELABAPDB5611057&prefLang=en_US
Description
Summary:The scientific goal of the present work is the development of a new molecular biomarker as a biomonitoring tool for early assessment of the biological effect of complex mixtures of pollutants (especially polycyclic aromatic hydrocarbons) and validation of the approach by comparison with standard methodologies. Hence, a DNA-based biosensor, which is able to detect the presence of compounds with affinity for DNA to measure their effect on the guanine base, was used in this research.

Similar Items