Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation
The objective of this study was to investigate the antibacterial activity and potential mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus. Results show that the length of the alkyl chain plays a pivotal role in eliciting the activity and octyl gallate (OG) exerted excell...
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ftleedsuniv:oai:eprints.whiterose.ac.uk:169763 2023-05-15T16:42:06+02:00 Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation Shi, Y-G Zhang, R-R Zhu, C-M Xu, M-F Gu, Q Ettelaie, R Lin, S Wang, Y-F Leng, X-Y 2021-06-01 text https://eprints.whiterose.ac.uk/169763/ https://eprints.whiterose.ac.uk/169763/1/FOODCHEM-D-20-06453.pdf en eng Elsevier BV https://eprints.whiterose.ac.uk/169763/1/FOODCHEM-D-20-06453.pdf Shi, Y-G, Zhang, R-R, Zhu, C-M et al. (6 more authors) (2021) Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation. Food Chemistry, 346. 128949. ISSN 0308-8146 cc_by_nc_nd_4 CC-BY-NC-ND Article NonPeerReviewed 2021 ftleedsuniv 2023-01-30T22:35:42Z The objective of this study was to investigate the antibacterial activity and potential mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus. Results show that the length of the alkyl chain plays a pivotal role in eliciting the activity and octyl gallate (OG) exerted excellent bactericidal activity through a multiple bactericidal mechanism. OG functions against both bacteria through damaging bacterial cell wall integrity, permeating into cells and then interacting with DNA, as well as disturbing the activity of the respiratory electron transport chain to induce a high-level toxic ROS (hydroxyl radicals) generation and up-regulation of the ROS genes. Also, electrospun nanofibers with OG have unique superiorities for maintaining the freshness of the icefish (4 °C). This research not only provides a more in-depth understanding of the interaction between OG and microorganisms but also highlights the great promise of using OG as a safe multi-functionalized food additive for food preservations. Article in Journal/Newspaper Icefish White Rose Research Online (Universities of Leeds, Sheffield & York) |
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Open Polar |
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White Rose Research Online (Universities of Leeds, Sheffield & York) |
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ftleedsuniv |
language |
English |
description |
The objective of this study was to investigate the antibacterial activity and potential mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus. Results show that the length of the alkyl chain plays a pivotal role in eliciting the activity and octyl gallate (OG) exerted excellent bactericidal activity through a multiple bactericidal mechanism. OG functions against both bacteria through damaging bacterial cell wall integrity, permeating into cells and then interacting with DNA, as well as disturbing the activity of the respiratory electron transport chain to induce a high-level toxic ROS (hydroxyl radicals) generation and up-regulation of the ROS genes. Also, electrospun nanofibers with OG have unique superiorities for maintaining the freshness of the icefish (4 °C). This research not only provides a more in-depth understanding of the interaction between OG and microorganisms but also highlights the great promise of using OG as a safe multi-functionalized food additive for food preservations. |
format |
Article in Journal/Newspaper |
author |
Shi, Y-G Zhang, R-R Zhu, C-M Xu, M-F Gu, Q Ettelaie, R Lin, S Wang, Y-F Leng, X-Y |
spellingShingle |
Shi, Y-G Zhang, R-R Zhu, C-M Xu, M-F Gu, Q Ettelaie, R Lin, S Wang, Y-F Leng, X-Y Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation |
author_facet |
Shi, Y-G Zhang, R-R Zhu, C-M Xu, M-F Gu, Q Ettelaie, R Lin, S Wang, Y-F Leng, X-Y |
author_sort |
Shi, Y-G |
title |
Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation |
title_short |
Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation |
title_full |
Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation |
title_fullStr |
Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation |
title_full_unstemmed |
Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation |
title_sort |
antimicrobial mechanism of alkyl gallates against escherichia coli and staphylococcus aureus and its combined effect with electrospun nanofibers on chinese taihu icefish preservation |
publisher |
Elsevier BV |
publishDate |
2021 |
url |
https://eprints.whiterose.ac.uk/169763/ https://eprints.whiterose.ac.uk/169763/1/FOODCHEM-D-20-06453.pdf |
genre |
Icefish |
genre_facet |
Icefish |
op_relation |
https://eprints.whiterose.ac.uk/169763/1/FOODCHEM-D-20-06453.pdf Shi, Y-G, Zhang, R-R, Zhu, C-M et al. (6 more authors) (2021) Antimicrobial mechanism of alkyl gallates against Escherichia coli and Staphylococcus aureus and its combined effect with electrospun nanofibers on Chinese Taihu icefish preservation. Food Chemistry, 346. 128949. ISSN 0308-8146 |
op_rights |
cc_by_nc_nd_4 |
op_rightsnorm |
CC-BY-NC-ND |
_version_ |
1766032550215548928 |