Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator
The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during c...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Other Non-Article Part of Journal/Newspaper |
Language: | unknown |
Published: |
2022
|
Subjects: | |
Online Access: | https://doi.org/10.26181/21569649.v1 https://figshare.com/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649 |
id |
ftlatrobeunivfig:oai:figshare.com:article/21569649 |
---|---|
record_format |
openpolar |
spelling |
ftlatrobeunivfig:oai:figshare.com:article/21569649 2023-05-15T14:35:58+02:00 Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator L Hu J Long Y Lin Z Gu H Su X Dong Z Lin Q Xiao N Batbayar B Bold L Deutschová S Ganusevich V Sokolov A Sokolov HR Patel PD Waters Jennifer Graves A Dixon S Pan X Zhan 2022-11-17T04:23:58Z https://doi.org/10.26181/21569649.v1 https://figshare.com/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649 unknown doi:10.26181/21569649.v1 https://figshare.com/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649 CC BY 4.0 CC-BY Genetics Ecology Female Animals Chromatin Tibet Hybridization Genetic Acclimatization Hypoxia Text Journal contribution 2022 ftlatrobeunivfig https://doi.org/10.26181/21569649.v1 2022-11-24T00:08:03Z The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory elements during hypoxic response and UV protection. Other Non-Article Part of Journal/Newspaper Arctic La Trobe University (Melbourne): Figshare Arctic |
institution |
Open Polar |
collection |
La Trobe University (Melbourne): Figshare |
op_collection_id |
ftlatrobeunivfig |
language |
unknown |
topic |
Genetics Ecology Female Animals Chromatin Tibet Hybridization Genetic Acclimatization Hypoxia |
spellingShingle |
Genetics Ecology Female Animals Chromatin Tibet Hybridization Genetic Acclimatization Hypoxia L Hu J Long Y Lin Z Gu H Su X Dong Z Lin Q Xiao N Batbayar B Bold L Deutschová S Ganusevich V Sokolov A Sokolov HR Patel PD Waters Jennifer Graves A Dixon S Pan X Zhan Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator |
topic_facet |
Genetics Ecology Female Animals Chromatin Tibet Hybridization Genetic Acclimatization Hypoxia |
description |
The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic, and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation. QTP animals have adapted to these extreme conditions, but whether they obtained genetic variations from the Arctic during cold adaptation, and how genomic mutations in non-coding regions regulate gene expression under hypoxia and intense UV environment, remain largely unknown. Here, we assemble a high-quality saker falcon genome and resequence populations across Eurasia. We identify female-biased hybridization with Arctic gyrfalcons in the last glacial maximum, that endowed eastern sakers with alleles conveying larger body size and changes in fat metabolism, predisposing their QTP cold adaptation. We discover that QTP hypoxia and UV adaptations mainly involve independent changes in non-coding genomic variants. Our study highlights key roles of gene flow from Arctic relatives during QTP hypothermia adaptation, and cis-regulatory elements during hypoxic response and UV protection. |
format |
Other Non-Article Part of Journal/Newspaper |
author |
L Hu J Long Y Lin Z Gu H Su X Dong Z Lin Q Xiao N Batbayar B Bold L Deutschová S Ganusevich V Sokolov A Sokolov HR Patel PD Waters Jennifer Graves A Dixon S Pan X Zhan |
author_facet |
L Hu J Long Y Lin Z Gu H Su X Dong Z Lin Q Xiao N Batbayar B Bold L Deutschová S Ganusevich V Sokolov A Sokolov HR Patel PD Waters Jennifer Graves A Dixon S Pan X Zhan |
author_sort |
L Hu |
title |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator |
title_short |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator |
title_full |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator |
title_fullStr |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator |
title_full_unstemmed |
Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator |
title_sort |
arctic introgression and chromatin regulation facilitated rapid qinghai-tibet plateau colonization by an avian predator |
publishDate |
2022 |
url |
https://doi.org/10.26181/21569649.v1 https://figshare.com/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_relation |
doi:10.26181/21569649.v1 https://figshare.com/articles/journal_contribution/Arctic_introgression_and_chromatin_regulation_facilitated_rapid_Qinghai-Tibet_Plateau_colonization_by_an_avian_predator/21569649 |
op_rights |
CC BY 4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.26181/21569649.v1 |
_version_ |
1766308691367165952 |