Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Objective . The objectives of this study were to investigate the incidence, aetiology and mortality of liver cirrhosis in Iceland and in Gothenburg in Sweden. Further objectives were progno...
Published in: | Scandinavian Journal of Gastroenterology |
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Online Access: | http://hdl.handle.net/2336/86463 https://doi.org/10.1080/00365520902912571 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/86463 2023-05-15T16:42:17+02:00 Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes Gunnarsdottir, S A Olsson, R Olafsson, S Cariglia, N Westin, J Thjodleifsson, B Bjornsson, E Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden. 2009-11-19 http://hdl.handle.net/2336/86463 https://doi.org/10.1080/00365520902912571 ENG n/a eng Informa Healthcare http://dx.doi.org/10.1080/00365520902912571 Scand. J. Gastroenterol. 2009, 44(8):984-93 1502-7708 19437344 doi:10.1080/00365520902912571 http://hdl.handle.net/2336/86463 Scandinavian journal of gastroenterology Liver Cirrhosis Alcoholic Mortality Article 2009 ftlandspitaliuni https://doi.org/10.1080/00365520902912571 2022-05-29T08:21:27Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Objective . The objectives of this study were to investigate the incidence, aetiology and mortality of liver cirrhosis in Iceland and in Gothenburg in Sweden. Further objectives were prognosis in relation to different aetiologies and to evaluate the relationship between alcohol consumption in these countries and the incidence of alcoholic cirrhosis in recent decades. The incidence and mortality of liver cirrhosis in Iceland has been reported to be the lowest in the Western world. There are very few data on aetiology, incidence and prognosis among cirrhotics in Sweden. Material and methods . All patients diagnosed with liver cirrhosis in Gothenburg (600,000 inhabitants) and Iceland (300,000 inhabitants) during the period 1994-2003 were included. Results . A total of 918 patients in Gothenburg and 98 in Iceland were identified. The annual incidence in Gothenburg was 15.3+/-2.4/100,000 compared to 3.3+/-1.2/100,000 in Iceland (p<0.0001). In Gothenburg, 69% were male and in Iceland 52% (p<0.001). In Gothenburg, 50% of the patients had alcoholic cirrhosis compared to 29% in Iceland (p<0.0001). In Gothenburg, the patients had a higher Child-Pugh score (9.0) (SD 2.5) compared to Iceland (7.3) (SD 2.7) (p<0.0001). There was no difference in survival between patients with alcoholic liver disease and those with other aetiologies. Conclusions . The incidence of liver cirrhosis is low in Iceland, i.e. 24% of the incidence in Gothenburg, due to the lower incidence of alcoholic and hepatitis C cirrhosis in Iceland. No increasing trends in the incidence of cirrhosis in these two countries were observed during the study period. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Scandinavian Journal of Gastroenterology 44 8 984 993 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
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language |
English |
topic |
Liver Cirrhosis Alcoholic Mortality |
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Liver Cirrhosis Alcoholic Mortality Gunnarsdottir, S A Olsson, R Olafsson, S Cariglia, N Westin, J Thjodleifsson, B Bjornsson, E Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes |
topic_facet |
Liver Cirrhosis Alcoholic Mortality |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Objective . The objectives of this study were to investigate the incidence, aetiology and mortality of liver cirrhosis in Iceland and in Gothenburg in Sweden. Further objectives were prognosis in relation to different aetiologies and to evaluate the relationship between alcohol consumption in these countries and the incidence of alcoholic cirrhosis in recent decades. The incidence and mortality of liver cirrhosis in Iceland has been reported to be the lowest in the Western world. There are very few data on aetiology, incidence and prognosis among cirrhotics in Sweden. Material and methods . All patients diagnosed with liver cirrhosis in Gothenburg (600,000 inhabitants) and Iceland (300,000 inhabitants) during the period 1994-2003 were included. Results . A total of 918 patients in Gothenburg and 98 in Iceland were identified. The annual incidence in Gothenburg was 15.3+/-2.4/100,000 compared to 3.3+/-1.2/100,000 in Iceland (p<0.0001). In Gothenburg, 69% were male and in Iceland 52% (p<0.001). In Gothenburg, 50% of the patients had alcoholic cirrhosis compared to 29% in Iceland (p<0.0001). In Gothenburg, the patients had a higher Child-Pugh score (9.0) (SD 2.5) compared to Iceland (7.3) (SD 2.7) (p<0.0001). There was no difference in survival between patients with alcoholic liver disease and those with other aetiologies. Conclusions . The incidence of liver cirrhosis is low in Iceland, i.e. 24% of the incidence in Gothenburg, due to the lower incidence of alcoholic and hepatitis C cirrhosis in Iceland. No increasing trends in the incidence of cirrhosis in these two countries were observed during the study period. |
author2 |
Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden. |
format |
Article in Journal/Newspaper |
author |
Gunnarsdottir, S A Olsson, R Olafsson, S Cariglia, N Westin, J Thjodleifsson, B Bjornsson, E |
author_facet |
Gunnarsdottir, S A Olsson, R Olafsson, S Cariglia, N Westin, J Thjodleifsson, B Bjornsson, E |
author_sort |
Gunnarsdottir, S A |
title |
Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes |
title_short |
Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes |
title_full |
Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes |
title_fullStr |
Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes |
title_full_unstemmed |
Liver cirrhosis in Iceland and Sweden: incidence, aetiology and outcomes |
title_sort |
liver cirrhosis in iceland and sweden: incidence, aetiology and outcomes |
publisher |
Informa Healthcare |
publishDate |
2009 |
url |
http://hdl.handle.net/2336/86463 https://doi.org/10.1080/00365520902912571 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1080/00365520902912571 Scand. J. Gastroenterol. 2009, 44(8):984-93 1502-7708 19437344 doi:10.1080/00365520902912571 http://hdl.handle.net/2336/86463 Scandinavian journal of gastroenterology |
op_doi |
https://doi.org/10.1080/00365520902912571 |
container_title |
Scandinavian Journal of Gastroenterology |
container_volume |
44 |
container_issue |
8 |
container_start_page |
984 |
op_container_end_page |
993 |
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1766032726043918336 |