Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study.
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field AIM: To establish the epidemiology of the grey crescent in a white population within the age range most susceptible to glaucoma. METHODS: Bruce Shields was first to use this term to describ...
Published in: | British Journal of Ophthalmology |
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Online Access: | http://hdl.handle.net/2336/82834 https://doi.org/10.1136/bjo.2004.044305 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/82834 2023-05-15T16:51:49+02:00 Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. Jonsson, O Damji, K F Jonasson, F Arnarsson, A Eysteinsson, T Sasaki, H Sasaki, K University of Ottawa Eye Institute, 501 Smyth Road, Ottawa, Ontario, Canada K1H 8L6. 2009-09-28 http://hdl.handle.net/2336/82834 https://doi.org/10.1136/bjo.2004.044305 en eng British Medical Association http://dx.doi.org/10.1136/bjo.2004.044305 Br J Ophthalmol. 2005, 89(1):36-9 0007-1161 15615743 doi:10.1136/bjo.2004.044305 http://hdl.handle.net/2336/82834 British journal of ophthalmology Aged 80 and over Atrophy Female Fluorescein Angiography Glaucoma Humans Iceland Male Middle Aged Optic Disk Optic Nerve Diseases Pigmentation Disorders Prevalence Sex Distribution Article 2009 ftlandspitaliuni https://doi.org/10.1136/bjo.2004.044305 2022-05-29T08:21:26Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field AIM: To establish the epidemiology of the grey crescent in a white population within the age range most susceptible to glaucoma. METHODS: Bruce Shields was first to use this term to describe a localised, physiological pigmentation of the optic nerve neuroretinal rim tissue that is distinct from peripapillary pigmentation. An experienced glaucomatologist (KFD) evaluated stereofundus photographs of the participants of the Reykjavik Eye Study (RES)-a random sample from the national population census including people 50 years and older. 1012 right eyes could be evaluated for grey crescent. RESULTS: The prevalence of grey crescent in the right eyes was 22.0% (95% CI 10 to 25). It was more commonly found in women (27.0%: 95% CI 23 to 30) than in men (17.0%: 95% CI 14 to 21), and was most often located temporally (36.9%), 360 degrees (15.9%), or nasally (15.4%). The spherical equivalent was +1.30 dioptres (D) for those with and +0.80 D for those without grey crescent (p = 0.002), respectively. Vertical optic disc diameters were 0.203 v 0.195 units (p<0.001). There was no difference in the prevalence of grey crescent in glaucomatous or non-glaucomatous eyes (OR = 1.05, 95% CI 0.49 to 2.26). The prevalence of a grey crescent was inversely related to the prevalence of peripapillary atrophy (p = 0.001). CONCLUSIONS: The grey crescent needs to be recognised as a physiological variant in order to avoid falsely labelling eyes as having glaucomatous optic nerve damage. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive British Journal of Ophthalmology 89 1 36 39 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Aged 80 and over Atrophy Female Fluorescein Angiography Glaucoma Humans Iceland Male Middle Aged Optic Disk Optic Nerve Diseases Pigmentation Disorders Prevalence Sex Distribution |
spellingShingle |
Aged 80 and over Atrophy Female Fluorescein Angiography Glaucoma Humans Iceland Male Middle Aged Optic Disk Optic Nerve Diseases Pigmentation Disorders Prevalence Sex Distribution Jonsson, O Damji, K F Jonasson, F Arnarsson, A Eysteinsson, T Sasaki, H Sasaki, K Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. |
topic_facet |
Aged 80 and over Atrophy Female Fluorescein Angiography Glaucoma Humans Iceland Male Middle Aged Optic Disk Optic Nerve Diseases Pigmentation Disorders Prevalence Sex Distribution |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field AIM: To establish the epidemiology of the grey crescent in a white population within the age range most susceptible to glaucoma. METHODS: Bruce Shields was first to use this term to describe a localised, physiological pigmentation of the optic nerve neuroretinal rim tissue that is distinct from peripapillary pigmentation. An experienced glaucomatologist (KFD) evaluated stereofundus photographs of the participants of the Reykjavik Eye Study (RES)-a random sample from the national population census including people 50 years and older. 1012 right eyes could be evaluated for grey crescent. RESULTS: The prevalence of grey crescent in the right eyes was 22.0% (95% CI 10 to 25). It was more commonly found in women (27.0%: 95% CI 23 to 30) than in men (17.0%: 95% CI 14 to 21), and was most often located temporally (36.9%), 360 degrees (15.9%), or nasally (15.4%). The spherical equivalent was +1.30 dioptres (D) for those with and +0.80 D for those without grey crescent (p = 0.002), respectively. Vertical optic disc diameters were 0.203 v 0.195 units (p<0.001). There was no difference in the prevalence of grey crescent in glaucomatous or non-glaucomatous eyes (OR = 1.05, 95% CI 0.49 to 2.26). The prevalence of a grey crescent was inversely related to the prevalence of peripapillary atrophy (p = 0.001). CONCLUSIONS: The grey crescent needs to be recognised as a physiological variant in order to avoid falsely labelling eyes as having glaucomatous optic nerve damage. |
author2 |
University of Ottawa Eye Institute, 501 Smyth Road, Ottawa, Ontario, Canada K1H 8L6. |
format |
Article in Journal/Newspaper |
author |
Jonsson, O Damji, K F Jonasson, F Arnarsson, A Eysteinsson, T Sasaki, H Sasaki, K |
author_facet |
Jonsson, O Damji, K F Jonasson, F Arnarsson, A Eysteinsson, T Sasaki, H Sasaki, K |
author_sort |
Jonsson, O |
title |
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. |
title_short |
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. |
title_full |
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. |
title_fullStr |
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. |
title_full_unstemmed |
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. |
title_sort |
epidemiology of the optic nerve grey crescent in the reykjavik eye study. |
publisher |
British Medical Association |
publishDate |
2009 |
url |
http://hdl.handle.net/2336/82834 https://doi.org/10.1136/bjo.2004.044305 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1136/bjo.2004.044305 Br J Ophthalmol. 2005, 89(1):36-9 0007-1161 15615743 doi:10.1136/bjo.2004.044305 http://hdl.handle.net/2336/82834 British journal of ophthalmology |
op_doi |
https://doi.org/10.1136/bjo.2004.044305 |
container_title |
British Journal of Ophthalmology |
container_volume |
89 |
container_issue |
1 |
container_start_page |
36 |
op_container_end_page |
39 |
_version_ |
1766041917079945216 |