Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Introduction: Middle lobe syndrome (MLS) is a relatively uncommon lung disease that is characterized by damage to the middle lobe and often needs surgical intervention. Objective: To study...
Published in: | The Clinical Respiratory Journal |
---|---|
Main Authors: | , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Blackwell Publishing Ltd
2009
|
Subjects: | |
Online Access: | http://hdl.handle.net/2336/80115 https://doi.org/10.1111/j.1752-699X.2008.00109.x |
id |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/80115 |
---|---|
record_format |
openpolar |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/80115 2023-05-15T16:48:44+02:00 Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment Einarsson, J T Einarsson, J G Isaksson, H Gudbjartsson, T Gudmundsson, G Department of Respiratory Medicine, Allergy and Sleep, Landspitali University Hospital, E-7 Fossvogur, IS-108 2009-09-07 http://hdl.handle.net/2336/80115 https://doi.org/10.1111/j.1752-699X.2008.00109.x en eng Blackwell Publishing Ltd http://dx.doi.org/10.1111/j.1752-699X.2008.00109.x Clin. Respir. J. 2009, 3(2):77-81 17526981 1752699X doi:10.1111/j.1752-699X.2008.00109.x http://hdl.handle.net/2336/80115 Clinical Respiratory Journal Middle Lobe Syndrome Bronchiectasis Article 2009 ftlandspitaliuni https://doi.org/10.1111/j.1752-699X.2008.00109.x 2022-05-29T08:21:24Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Introduction: Middle lobe syndrome (MLS) is a relatively uncommon lung disease that is characterized by damage to the middle lobe and often needs surgical intervention. Objective: To study clinical, radiological and histological features of all patients who underwent surgical resection for MLS in Iceland over a 13-year period, including evaluation of surgical outcome. Methods: Information on patients who underwent surgery of the right middle lobe in Iceland from 1984 to 2006 was obtained from a centralized diagnosis and pathology registry. Clinical data were collected retrospectively from clinical records from hospitals and from private offices. All pathology specimens were reviewed. Results: We studied 18 patients, 3 males and 15 females between the ages 2 and 86 years (mean 55). The most common clinical features were recurrent infection (n = 15), chronic cough with productive sputum (n = 9), chest pain (n = 8) or dyspnea (n = 7). The most common findings on chest radiographs and on computerized tomography of the chest were atelectasis, consolidation and bronchiectasis. One patient had a foreign body. The most common major histological finding was bronchiectasis in nine patients, and two had foreign body reaction. Minor findings included bronchiolitis, organizing pneumonia and peribronchial inflammation. All patients survived surgery with minor peri- and postoperative complications. Conclusion: MLS is more common in females, and recurrent infections, chronic productive cough and dyspnea were the most common symptoms. Bronchiectasis is the most common histological finding. MLS can be treated effectively with lobectomy with low mortality and rate of complications. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive The Clinical Respiratory Journal 3 2 77 81 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Middle Lobe Syndrome Bronchiectasis |
spellingShingle |
Middle Lobe Syndrome Bronchiectasis Einarsson, J T Einarsson, J G Isaksson, H Gudbjartsson, T Gudmundsson, G Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment |
topic_facet |
Middle Lobe Syndrome Bronchiectasis |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Introduction: Middle lobe syndrome (MLS) is a relatively uncommon lung disease that is characterized by damage to the middle lobe and often needs surgical intervention. Objective: To study clinical, radiological and histological features of all patients who underwent surgical resection for MLS in Iceland over a 13-year period, including evaluation of surgical outcome. Methods: Information on patients who underwent surgery of the right middle lobe in Iceland from 1984 to 2006 was obtained from a centralized diagnosis and pathology registry. Clinical data were collected retrospectively from clinical records from hospitals and from private offices. All pathology specimens were reviewed. Results: We studied 18 patients, 3 males and 15 females between the ages 2 and 86 years (mean 55). The most common clinical features were recurrent infection (n = 15), chronic cough with productive sputum (n = 9), chest pain (n = 8) or dyspnea (n = 7). The most common findings on chest radiographs and on computerized tomography of the chest were atelectasis, consolidation and bronchiectasis. One patient had a foreign body. The most common major histological finding was bronchiectasis in nine patients, and two had foreign body reaction. Minor findings included bronchiolitis, organizing pneumonia and peribronchial inflammation. All patients survived surgery with minor peri- and postoperative complications. Conclusion: MLS is more common in females, and recurrent infections, chronic productive cough and dyspnea were the most common symptoms. Bronchiectasis is the most common histological finding. MLS can be treated effectively with lobectomy with low mortality and rate of complications. |
author2 |
Department of Respiratory Medicine, Allergy and Sleep, Landspitali University Hospital, E-7 Fossvogur, IS-108 |
format |
Article in Journal/Newspaper |
author |
Einarsson, J T Einarsson, J G Isaksson, H Gudbjartsson, T Gudmundsson, G |
author_facet |
Einarsson, J T Einarsson, J G Isaksson, H Gudbjartsson, T Gudmundsson, G |
author_sort |
Einarsson, J T |
title |
Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment |
title_short |
Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment |
title_full |
Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment |
title_fullStr |
Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment |
title_full_unstemmed |
Middle lobe syndrome: A nationwide study on clinicopathological features and surgical treatment |
title_sort |
middle lobe syndrome: a nationwide study on clinicopathological features and surgical treatment |
publisher |
Blackwell Publishing Ltd |
publishDate |
2009 |
url |
http://hdl.handle.net/2336/80115 https://doi.org/10.1111/j.1752-699X.2008.00109.x |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1111/j.1752-699X.2008.00109.x Clin. Respir. J. 2009, 3(2):77-81 17526981 1752699X doi:10.1111/j.1752-699X.2008.00109.x http://hdl.handle.net/2336/80115 Clinical Respiratory Journal |
op_doi |
https://doi.org/10.1111/j.1752-699X.2008.00109.x |
container_title |
The Clinical Respiratory Journal |
container_volume |
3 |
container_issue |
2 |
container_start_page |
77 |
op_container_end_page |
81 |
_version_ |
1766038822042206208 |