Ristilkrabbamein á Íslandi árin 1955-2004 : faraldsfræðileg og meinafræðileg athugun og samanburður á kynjum

• Main Authors: Pétur Snæbjörnsson, Lárus Jónasson, Þorvaldur Jónsson, Páll Helgi Möller, Ásgeir Theodórs, Jón Gunnlaugur Jónasson
• Other Authors: Læknadeild Hĺ
• Format: Article in Journal/Newspaper
• Language: Icelandic
• Published: Læknafélag Íslands, Læknafélag Reykjavíkur 2009
• Subjects: Ristilkrabbamein; Meinafræði; Adenocarcinoma; Mucinous; Adult; Age Distribution; Aged; 80 and over; Colectomy; Colonic Neoplasms; Female; Iceland; Incidence; Linear Models; Male; Middle Aged; Neoplasm Staging; Sex Distribution; Sex Factors; Time Factors; TNM; Smella
• Online Access: http://hdl.handle.net/2336/74773

Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open OBJECTIVE: Colon cancer is the third most common cancer in Iceland. The aim of this study was to analyze the epidemiology and histopathology of colon cancer in Iceland, resection rate and the difference between men and women. MATERIAL AND METHODS: Pathology and autopsy reports for all patients diagnosed with colon cancer between 1955 and 2004 where reviewed. All the histopathology material was re-evaluated. Demographical information and pathological findings were registered. Age-standardized incidence was calculated for both men and women. Gender difference was evaluated. Time trend was evaluated by linear regression. RESULTS: After re-evaluation 2293 cases remained (1148 males and 1145 females). The incidence increased for men from 7.5, to 22.2/105 and for women from 8.6 to 15.1/105. Most tumors were located in the sigmoid colon (35%). Surgical rate increased from 50% to 85%. Adenocarcinomas where 84% and mucinous adenocarcinoma 7%. Altogether 7% of cases were TNM-stage I, 32% were stage II, 24% stage III, 21% in stage IV and stage was unknown in 16% of cases. Slight gender difference was observed regarding grade, vessel invasion, depth of invasion and anatomic subsite. CONCLUSION: Incidence of colon cancer increased considerably, mainly for men. Surgical rate and pathology of colon cancer is similar to that reported elsewhere except that there are somewhat fewer cases in TNM-stage I. Little gender difference was observed in the pathological parameters analysed. Inngangur: Krabbamein í ristli er þriðja algengasta krabbamein á Íslandi. Þessi rannsókn gerir grein fyrir faralds- og meinafræði ristilkrabbameins á Íslandi, skurðtíðni og kynjamun. Efniviður og aðferðir: Vefjasvör og krufningaskýrslur þeirra sem greindust með ristilkrabbamein á árunum 1955-2004 voru yfirfarin. Vefjasýni sjúklinga voru endurskoðuð og meinafræðilegir og lýðfræðilegir þættir skráðir. Aldursstaðlað nýgengi var reiknað fyrir bæði kyn. ...