Notkun sýklalyfja á Landspítala

• Main Authors: Arnar Þór Guðjónsson, Karl G. Kristinsson, Sigurður Guðmundsson
• Format: Article in Journal/Newspaper
• Language: Icelandic
• Published: Læknafélag Íslands, Læknafélag Reykjavíkur 2009
• Subjects: Sýklalyf; Lyfjanotkun; Anti-Bacterial Agents; Antibiotics; Drug Utilization Review; Smella; Vikna; Iceland
• Online Access: http://hdl.handle.net/2336/67357

Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Introduction: Antibiotics are responsible for 20-25% of the total drug-cost in the larger hospitals in Iceland. Studies from other countries, both in Europe and North-America suggest that 40-70% of both antibiotic therapy and prophylaxis is inappropriate in the larger teaching hospitals. We undertook a prospective study to determine the patterns of antimicrobial use in a university hospital. Methods: Data on antibiotic prescriptions were collected over two four week periods in April and August 1994 on 12 wards at the National University Hospital. Results: During the eight weeks 302 (30%) of 1020 hospitalized medical, surgical and gynecological patients received one or more courses of antimicrobial therapy. Presumptive infection was the reason for therapy in 73% of the cases, prophylaxis in 35% and both therapy and prophylaxis in 8%. Cephalosporins were the most commonly used drugs for antimicrobial therapy and cloxacillin for prophylaxis. Therapy was judged appropriate in only 45% of the courses. Poor drug choice (bacterologically, pharmacologically), misguided prophylaxis, wrong drug dosage or unneccessary therapy were the most frequent reason for inappropriate therapy. Conclusion: Because of the worldwide increase of antibiotic-resistant strains the results of this study clearly indicate the need for additional measures to improve antibiotic use. Inngangur: Um 20-25% lyfjakostnaðar apóteka stærri sjúkrahúsa hérlendis er vegna sýklalyfja. Rannsóknir frá nálægum löndum benda til að um 40-70% sýklalyfjaávísana á stærri kennslusjúkrahúsum sé ábótavant. Litlar upplýsingar lágu fyrir um hvernig þessu væri háttað hérlendis. Við könnuðum því ávísanir á sýklalyf um átta vikna skeið á ýmsum deildum Landspítala. Aðferðir: Efniviður var útskrifaðir sjúklingar á lyflækninga-, handlækninga-, krabbameins- og kvennadeildum Landspítalans (að undanskildum fæðinga- og meðgöngudeild) á tveimur fjögurra vikna tímabilum, í apríl og ...