Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open BACKGROUND: Foodborne or orofecal transmitted infections can have influence on health by direct consequences of the infection and indirectly by modulating the immune system. OBJECTIVES: To investigate th...
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Format: | Article in Journal/Newspaper |
Language: | Icelandic |
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Læknafélag Íslands, Læknafélag Reykjavíkur
2006
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Online Access: | http://hdl.handle.net/2336/6604 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/6604 2023-05-15T16:49:39+02:00 Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni Foodborne infections in Iceland. Relationship to allergy and lung function Hulda Ásbjörnsdóttir Rúna B Sigurjónsdóttir Signý V Sveinsdóttir Alda Birgisdóttir Davíð Gíslason Christer Jansson Ísleifur Ólafsson Þórarinn Gíslason Bjarni Þjóðleifsson 2006-12-18 YES http://hdl.handle.net/2336/6604 ice is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www.laeknabladid.is Læknablaðið 2006, 92(6):437-44 0023-7213 16819003 PAD12 GAS12 http://hdl.handle.net/2336/6604 Læknablaðið Faraldsfræði Smitsjúkdómar Lungnasjúkdómar Ofnæmi Veirur Fræðigreinar LBL12 Adult Animals Antibodies Bacterial Protozoan Asthma English Abstract Enzyme-Linked Immunosorbent Assay Female Food Poisoning Forced Expiratory Volume Helicobacter Infections Helicobacter pylori Hepatitis A Hepatitis A virus Humans Hypersensitivity Immediate Iceland/epidemiology Immunoglobulin G Logistic Models Lung Male Middle Aged Odds Ratio Prevalence Questionnaires Toxoplasma Article 2006 ftlandspitaliuni 2022-05-29T08:20:55Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open BACKGROUND: Foodborne or orofecal transmitted infections can have influence on health by direct consequences of the infection and indirectly by modulating the immune system. OBJECTIVES: To investigate the prevalence and risk factors for T. gondii, H. pylori and HAV infection in the Icelandic population and their influence on atopy, allergy related lung symptoms and lung function. MATERIAL AND METHODS: Blood samples were collected in 1999-2001 from 505 subjects in age group 28-52, randomly selected from the Icelandic population. The presence of T. gondii, H. pylori and HAV IgG antibodies was determined by an ELISA method. Allergy related lung symptoms were assessed with questionnaire and IgE sensitization and lung function measured. X(2) test was used to test for trend but unadjusted logistic regression for comparison of IgG prevalence. Multiple logistic regression was used to calculate adjusted odds ratios and 95% confidence intervals for different infections factors. RESULTS: The prevalence of antibodies was 9.8%, for T. gondii, 36.3% for H. pylori and 4.9% for HAV. Attending day care before the age of 3 years was a risk factor for having T. gondii antibodies. The prevalence of H. pylori increased with age and smoking. The infections were not associated with the prevalence of asthma or atopy. Having IgG antibodies against T. gondii was, however, associated with an increased risk of having FEV/FVC ratio below 70%. CONCLUSION: T. gondii, H. pylori and H AV infection does not influence the prevalence of atopy or asthma. The data indicated that infection with T. gondii might be associated with a diminished lung function. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Smella ENVELOPE(29.443,29.443,69.896,69.896) |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Faraldsfræði Smitsjúkdómar Lungnasjúkdómar Ofnæmi Veirur Fræðigreinar LBL12 Adult Animals Antibodies Bacterial Protozoan Asthma English Abstract Enzyme-Linked Immunosorbent Assay Female Food Poisoning Forced Expiratory Volume Helicobacter Infections Helicobacter pylori Hepatitis A Hepatitis A virus Humans Hypersensitivity Immediate Iceland/epidemiology Immunoglobulin G Logistic Models Lung Male Middle Aged Odds Ratio Prevalence Questionnaires Toxoplasma |
spellingShingle |
Faraldsfræði Smitsjúkdómar Lungnasjúkdómar Ofnæmi Veirur Fræðigreinar LBL12 Adult Animals Antibodies Bacterial Protozoan Asthma English Abstract Enzyme-Linked Immunosorbent Assay Female Food Poisoning Forced Expiratory Volume Helicobacter Infections Helicobacter pylori Hepatitis A Hepatitis A virus Humans Hypersensitivity Immediate Iceland/epidemiology Immunoglobulin G Logistic Models Lung Male Middle Aged Odds Ratio Prevalence Questionnaires Toxoplasma Hulda Ásbjörnsdóttir Rúna B Sigurjónsdóttir Signý V Sveinsdóttir Alda Birgisdóttir Davíð Gíslason Christer Jansson Ísleifur Ólafsson Þórarinn Gíslason Bjarni Þjóðleifsson Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni |
topic_facet |
Faraldsfræði Smitsjúkdómar Lungnasjúkdómar Ofnæmi Veirur Fræðigreinar LBL12 Adult Animals Antibodies Bacterial Protozoan Asthma English Abstract Enzyme-Linked Immunosorbent Assay Female Food Poisoning Forced Expiratory Volume Helicobacter Infections Helicobacter pylori Hepatitis A Hepatitis A virus Humans Hypersensitivity Immediate Iceland/epidemiology Immunoglobulin G Logistic Models Lung Male Middle Aged Odds Ratio Prevalence Questionnaires Toxoplasma |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open BACKGROUND: Foodborne or orofecal transmitted infections can have influence on health by direct consequences of the infection and indirectly by modulating the immune system. OBJECTIVES: To investigate the prevalence and risk factors for T. gondii, H. pylori and HAV infection in the Icelandic population and their influence on atopy, allergy related lung symptoms and lung function. MATERIAL AND METHODS: Blood samples were collected in 1999-2001 from 505 subjects in age group 28-52, randomly selected from the Icelandic population. The presence of T. gondii, H. pylori and HAV IgG antibodies was determined by an ELISA method. Allergy related lung symptoms were assessed with questionnaire and IgE sensitization and lung function measured. X(2) test was used to test for trend but unadjusted logistic regression for comparison of IgG prevalence. Multiple logistic regression was used to calculate adjusted odds ratios and 95% confidence intervals for different infections factors. RESULTS: The prevalence of antibodies was 9.8%, for T. gondii, 36.3% for H. pylori and 4.9% for HAV. Attending day care before the age of 3 years was a risk factor for having T. gondii antibodies. The prevalence of H. pylori increased with age and smoking. The infections were not associated with the prevalence of asthma or atopy. Having IgG antibodies against T. gondii was, however, associated with an increased risk of having FEV/FVC ratio below 70%. CONCLUSION: T. gondii, H. pylori and H AV infection does not influence the prevalence of atopy or asthma. The data indicated that infection with T. gondii might be associated with a diminished lung function. |
format |
Article in Journal/Newspaper |
author |
Hulda Ásbjörnsdóttir Rúna B Sigurjónsdóttir Signý V Sveinsdóttir Alda Birgisdóttir Davíð Gíslason Christer Jansson Ísleifur Ólafsson Þórarinn Gíslason Bjarni Þjóðleifsson |
author_facet |
Hulda Ásbjörnsdóttir Rúna B Sigurjónsdóttir Signý V Sveinsdóttir Alda Birgisdóttir Davíð Gíslason Christer Jansson Ísleifur Ólafsson Þórarinn Gíslason Bjarni Þjóðleifsson |
author_sort |
Hulda Ásbjörnsdóttir |
title |
Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni |
title_short |
Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni |
title_full |
Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni |
title_fullStr |
Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni |
title_full_unstemmed |
Algengi IgG mótefna gegn Toxoplasma gondii, Helicobacter pylori og lifrarbólguveiru A á Íslandi. Tengsl við ofnæmi og lungnaeinkenni |
title_sort |
algengi igg mótefna gegn toxoplasma gondii, helicobacter pylori og lifrarbólguveiru a á íslandi. tengsl við ofnæmi og lungnaeinkenni |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2006 |
url |
http://hdl.handle.net/2336/6604 |
long_lat |
ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
Smella |
geographic_facet |
Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.laeknabladid.is Læknablaðið 2006, 92(6):437-44 0023-7213 16819003 PAD12 GAS12 http://hdl.handle.net/2336/6604 Læknablaðið |
_version_ |
1766039790124269568 |