Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field AIM: To compare the consumption of the cow milk proteins A1 and B beta-casein among children and adolescents in Iceland and Scandinavia (Norway, Denmark, Sweden and Finland) as this might e...
Published in: | Annals of Nutrition and Metabolism |
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Online Access: | http://hdl.handle.net/2336/6444 https://doi.org/10.1159/000090738 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/6444 2023-05-15T16:45:39+02:00 Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia Birgisdottir, B E Hill, J P Thorsson, A V Thorsdottir, I 2006-12-07 YES http://hdl.handle.net/2336/6444 https://doi.org/10.1159/000090738 en eng Karger http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=90738&Ausgabe=231622&ProduktNr=223977&filename=90738.pdf Ann. Nutr. Metab. 2006, 50(3):177-83 0250-6807 16407643 doi:10.1159/000090738 NUR12 PED12 http://hdl.handle.net/2336/6444 Adolescent Age Factors Animals Caseins Cattle Child Preschool Comparative Study Dairy Products Diabetes Mellitus Type 1 Diet Surveys Female Health Surveys Humans Iceland/epidemiology Incidence Male Research Support Non-U.S. Gov't Scandinavia/epidemiology Article 2006 ftlandspitaliuni https://doi.org/10.1159/000090738 2022-05-29T08:20:55Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field AIM: To compare the consumption of the cow milk proteins A1 and B beta-casein among children and adolescents in Iceland and Scandinavia (Norway, Denmark, Sweden and Finland) as this might explain the lower incidence of type 1 diabetes (per 100,000/year, 0-14 years) in Iceland. METHODS: The consumption of A1 beta-casein in each country among 2- and 11- to 14-year-old children was calculated from results on food intake and on cow milk protein concentration. The consumption values were then compared and evaluated against the incidence of type 1 diabetes. RESULTS: There was a significant difference between the consumption of A1 (p = 0.034) as well as the sum of A1 and B (p = 0.021) beta-casein in Iceland and Scandinavia for 2-year-old children. In the same age group, consumption of A1 beta-casein correlated with the incidence of type 1 diabetes in the countries (r = 0.9; p = 0.037). No significant difference in consumption of A1 or the sum of A1 and B beta-casein was found for 11- to 14-year-old adolescents. CONCLUSION: This study supports that lower consumption of A1 beta-casein might be related to the lower incidence of type 1 diabetes in Iceland than in Scandinavia. Additionally it indicates that consumption in young childhood might be of more importance for the development of the disease incidence than consumption in adolescence. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Norway Annals of Nutrition and Metabolism 50 3 177 183 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adolescent Age Factors Animals Caseins Cattle Child Preschool Comparative Study Dairy Products Diabetes Mellitus Type 1 Diet Surveys Female Health Surveys Humans Iceland/epidemiology Incidence Male Research Support Non-U.S. Gov't Scandinavia/epidemiology |
spellingShingle |
Adolescent Age Factors Animals Caseins Cattle Child Preschool Comparative Study Dairy Products Diabetes Mellitus Type 1 Diet Surveys Female Health Surveys Humans Iceland/epidemiology Incidence Male Research Support Non-U.S. Gov't Scandinavia/epidemiology Birgisdottir, B E Hill, J P Thorsson, A V Thorsdottir, I Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia |
topic_facet |
Adolescent Age Factors Animals Caseins Cattle Child Preschool Comparative Study Dairy Products Diabetes Mellitus Type 1 Diet Surveys Female Health Surveys Humans Iceland/epidemiology Incidence Male Research Support Non-U.S. Gov't Scandinavia/epidemiology |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field AIM: To compare the consumption of the cow milk proteins A1 and B beta-casein among children and adolescents in Iceland and Scandinavia (Norway, Denmark, Sweden and Finland) as this might explain the lower incidence of type 1 diabetes (per 100,000/year, 0-14 years) in Iceland. METHODS: The consumption of A1 beta-casein in each country among 2- and 11- to 14-year-old children was calculated from results on food intake and on cow milk protein concentration. The consumption values were then compared and evaluated against the incidence of type 1 diabetes. RESULTS: There was a significant difference between the consumption of A1 (p = 0.034) as well as the sum of A1 and B (p = 0.021) beta-casein in Iceland and Scandinavia for 2-year-old children. In the same age group, consumption of A1 beta-casein correlated with the incidence of type 1 diabetes in the countries (r = 0.9; p = 0.037). No significant difference in consumption of A1 or the sum of A1 and B beta-casein was found for 11- to 14-year-old adolescents. CONCLUSION: This study supports that lower consumption of A1 beta-casein might be related to the lower incidence of type 1 diabetes in Iceland than in Scandinavia. Additionally it indicates that consumption in young childhood might be of more importance for the development of the disease incidence than consumption in adolescence. |
format |
Article in Journal/Newspaper |
author |
Birgisdottir, B E Hill, J P Thorsson, A V Thorsdottir, I |
author_facet |
Birgisdottir, B E Hill, J P Thorsson, A V Thorsdottir, I |
author_sort |
Birgisdottir, B E |
title |
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia |
title_short |
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia |
title_full |
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia |
title_fullStr |
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia |
title_full_unstemmed |
Lower consumption of cow milk protein A1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in Iceland than in Scandinavia |
title_sort |
lower consumption of cow milk protein a1 beta-casein at 2 years of age, rather than consumption among 11- to 14-year-old adolescents, may explain the lower incidence of type 1 diabetes in iceland than in scandinavia |
publisher |
Karger |
publishDate |
2006 |
url |
http://hdl.handle.net/2336/6444 https://doi.org/10.1159/000090738 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=90738&Ausgabe=231622&ProduktNr=223977&filename=90738.pdf Ann. Nutr. Metab. 2006, 50(3):177-83 0250-6807 16407643 doi:10.1159/000090738 NUR12 PED12 http://hdl.handle.net/2336/6444 |
op_doi |
https://doi.org/10.1159/000090738 |
container_title |
Annals of Nutrition and Metabolism |
container_volume |
50 |
container_issue |
3 |
container_start_page |
177 |
op_container_end_page |
183 |
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1766035807184879616 |