Exopolysaccharides from Cyanobacterium aponinum induce a regulatory dendritic cell phenotype and inhibit SYK and CLEC7A expression in dendritic cells, T cells and keratinocytes.

• Published in: International Immunopharmacology
• Main Authors: Gudmundsdottir, Asa B, Brynjolfsdottir, Asa, Olafsdottir, Elin Soffia, Hardardottir, Ingibjorg, Freysdottir, Jona
• Other Authors: 1 Faculty of Medicine, University of Iceland, Biomedical Center, Vatnsmyrarvegur 16, IS-101 Reykjavik, Iceland; Department of Immunology, Landspitali-The National University Hospital of Iceland, Bld 14 at Eiriksgata, IS-101 Reykjavik, Iceland; Center for Rheumatology Research, Landspitali-The National University Hospital of Iceland, Bld 14 at Eiriksgata, IS-101 Reykjavik, Iceland. 2 Blue Lagoon, Nordurljosavegur 9, IS-240 Grindavik, Iceland. 3 Faculty of Pharmaceutical Sciences, University of Iceland, Hofsvallagata 53, IS-107 Reykjavik, Iceland. 4 Faculty of Medicine, University of Iceland, Biomedical Center, Vatnsmyrarvegur 16, IS-101 Reykjavik, Iceland; Department of Immunology, Landspitali-The National University Hospital of Iceland, Bld 14 at Eiriksgata, IS-101 Reykjavik, Iceland. 5 Faculty of Medicine, University of Iceland, Biomedical Center, Vatnsmyrarvegur 16, IS-101 Reykjavik, Iceland; Department of Immunology, Landspitali-The National University Hospital of Iceland, Bld 14 at Eiriksgata, IS-101 Reykjavik, Iceland; Center for Rheumatology Research, Landspitali-The National University Hospital of Iceland, Bld 14 at Eiriksgata, IS-101 Reykjavik, Iceland. Electronic address: [e-mail].
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier Science 2019
• Subjects: CAMP; CLEC7A; Dendritic cells; Keratinocytes; Syk signaling pathway; T cells; Sóríasis; Psoriasis; Blue Lagoon; Iceland
• Online Access: http://hdl.handle.net/2336/620926; https://doi.org/10.1016/j.intimp.2019.01.044

To access publisher's full text version of this article click on the hyperlink below Regular bathing in the Blue Lagoon has beneficial effects on psoriasis. Previously, we showed that exopolysaccharides (EPS-Ca) secreted by Cyanobacterium aponinum, a dominating organism in the Blue Lagoon, incr...