Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis.
To access publisher's full text version of this article click on the hyperlink below To study the outcome of acute pancreatitis and risk factors for recurrent and chronic pancreatitis in a population based cohort of patients with first-time acute pancreatitis. All patients with first-time acute...
Published in: | Scandinavian Journal of Gastroenterology |
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Online Access: | http://hdl.handle.net/2336/620901 https://doi.org/10.1080/00365521.2018.1550670 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620901 2023-05-15T16:50:57+02:00 Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. Magnusdottir, Berglind A Baldursdottir, Maria B Kalaitzakis, Evangelos Björnsson, Einar S 1 a Faculty of Medicine , University of Iceland , Reykjavík , Iceland. 2 b Digestive Disease Center, Copenhagen University Hospital/Herlev, University of Copenhagen , Copenhagen , Denmark. 3 c Department of Gastroenterology , Landspitali University Hospital Reykjavik , Reykjavík , Iceland. 2019-05 http://hdl.handle.net/2336/620901 https://doi.org/10.1080/00365521.2018.1550670 en eng Taylor & Francis https://www.tandfonline.com/doi/full/10.1080/00365521.2018.1550670 Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. 2019, 54(1):87-94 Scand J Gastroenterol 1502-7708 30700163 doi:10.1080/00365521.2018.1550670 http://hdl.handle.net/2336/620901 Scandinavian journal of gastroenterology Landspitali Access - LSH-aðgangur Scandinavian journal of gastroenterology Pancreas alcohol cholecystectomy gallstones natural history Brisbólga Pancreatitis Chronic Alcoholic Article 2019 ftlandspitaliuni https://doi.org/10.1080/00365521.2018.1550670 2022-05-29T08:22:25Z To access publisher's full text version of this article click on the hyperlink below To study the outcome of acute pancreatitis and risk factors for recurrent and chronic pancreatitis in a population based cohort of patients with first-time acute pancreatitis. All patients with first-time acute pancreatitis from 2006-2015 in Iceland were retrospectively evaluated. Medical records were scrutinized and relevant data extracted. 1102 cases of first-time acute pancreatitis were identified: mean age 56yr, 46% female, 41% biliary, 21% alcohol, 26% idiopathic, 13% other causes, mean follow-up 4yr. 21% had ≥1 recurrent acute pancreatitis which was independently related to alcoholic (vs. biliary hazard ratio (HR) 2.29, 95% confidence interval (CI) 1.51-3.46), male gender (HR 1.48, 95%CI 1.08-2.04), and smoking (HR 1.62, 95%CI 1.15-2.28). 3.7% developed chronic pancreatitis. Independent predictors were recurrent acute pancreatitis (HR 8.79, 95%CI 3.94-19.62), alcoholic (vs. biliary HR 9.16, 95%CI 2.71-30.9), local complications (HR 4.77, 95%CI 1.93-11.79), and organ-failure (HR 2.86, 95%CI 1.10-7.42). Recurrent acute pancreatitis occurred in one-fifth of patients. Development of chronic pancreatitis was infrequent. Both recurrent acute pancreatitis and chronic pancreatitis were related to alcoholic acute pancreatitis, while recurrent acute pancreatitis was associated with smoking and male gender, and chronic pancreatitis to recurrent acute pancreatitis, organ-failure, and local complications. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Scandinavian Journal of Gastroenterology 54 1 87 94 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Pancreas alcohol cholecystectomy gallstones natural history Brisbólga Pancreatitis Chronic Alcoholic |
spellingShingle |
Pancreas alcohol cholecystectomy gallstones natural history Brisbólga Pancreatitis Chronic Alcoholic Magnusdottir, Berglind A Baldursdottir, Maria B Kalaitzakis, Evangelos Björnsson, Einar S Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
topic_facet |
Pancreas alcohol cholecystectomy gallstones natural history Brisbólga Pancreatitis Chronic Alcoholic |
description |
To access publisher's full text version of this article click on the hyperlink below To study the outcome of acute pancreatitis and risk factors for recurrent and chronic pancreatitis in a population based cohort of patients with first-time acute pancreatitis. All patients with first-time acute pancreatitis from 2006-2015 in Iceland were retrospectively evaluated. Medical records were scrutinized and relevant data extracted. 1102 cases of first-time acute pancreatitis were identified: mean age 56yr, 46% female, 41% biliary, 21% alcohol, 26% idiopathic, 13% other causes, mean follow-up 4yr. 21% had ≥1 recurrent acute pancreatitis which was independently related to alcoholic (vs. biliary hazard ratio (HR) 2.29, 95% confidence interval (CI) 1.51-3.46), male gender (HR 1.48, 95%CI 1.08-2.04), and smoking (HR 1.62, 95%CI 1.15-2.28). 3.7% developed chronic pancreatitis. Independent predictors were recurrent acute pancreatitis (HR 8.79, 95%CI 3.94-19.62), alcoholic (vs. biliary HR 9.16, 95%CI 2.71-30.9), local complications (HR 4.77, 95%CI 1.93-11.79), and organ-failure (HR 2.86, 95%CI 1.10-7.42). Recurrent acute pancreatitis occurred in one-fifth of patients. Development of chronic pancreatitis was infrequent. Both recurrent acute pancreatitis and chronic pancreatitis were related to alcoholic acute pancreatitis, while recurrent acute pancreatitis was associated with smoking and male gender, and chronic pancreatitis to recurrent acute pancreatitis, organ-failure, and local complications. |
author2 |
1 a Faculty of Medicine , University of Iceland , Reykjavík , Iceland. 2 b Digestive Disease Center, Copenhagen University Hospital/Herlev, University of Copenhagen , Copenhagen , Denmark. 3 c Department of Gastroenterology , Landspitali University Hospital Reykjavik , Reykjavík , Iceland. |
format |
Article in Journal/Newspaper |
author |
Magnusdottir, Berglind A Baldursdottir, Maria B Kalaitzakis, Evangelos Björnsson, Einar S |
author_facet |
Magnusdottir, Berglind A Baldursdottir, Maria B Kalaitzakis, Evangelos Björnsson, Einar S |
author_sort |
Magnusdottir, Berglind A |
title |
Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
title_short |
Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
title_full |
Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
title_fullStr |
Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
title_full_unstemmed |
Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
title_sort |
risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. |
publisher |
Taylor & Francis |
publishDate |
2019 |
url |
http://hdl.handle.net/2336/620901 https://doi.org/10.1080/00365521.2018.1550670 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Scandinavian journal of gastroenterology |
op_relation |
https://www.tandfonline.com/doi/full/10.1080/00365521.2018.1550670 Risk factors for chronic and recurrent pancreatitis after first attack of acute pancreatitis. 2019, 54(1):87-94 Scand J Gastroenterol 1502-7708 30700163 doi:10.1080/00365521.2018.1550670 http://hdl.handle.net/2336/620901 Scandinavian journal of gastroenterology |
op_rights |
Landspitali Access - LSH-aðgangur |
op_doi |
https://doi.org/10.1080/00365521.2018.1550670 |
container_title |
Scandinavian Journal of Gastroenterology |
container_volume |
54 |
container_issue |
1 |
container_start_page |
87 |
op_container_end_page |
94 |
_version_ |
1766041072371236864 |