Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland.

To access publisher's full text version of this article click on the hyperlink below We studied the outcome of pulmonary resection with curative intent for non-small cell lung cancer (NSCLC) in a nationwide study covering a 24-year period, focusing on survival. All patients who underwent pulmon...

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Bibliographic Details
Published in:Annals of Translational Medicine
Main Authors: Halldorsson, Hannes, Orrason, Andri Wilberg, Oskarsdottir, Gudrun Nina, Petursdottir, Astridur, Fridriksson, Bjorn Mar, Magnusson, Magnus Karl, Jonsson, Steinn, Gudbjartsson, Tomas
Other Authors: 1 Department of Cardiothoracic Surgery, Landspitali University Hospital, Reykjavik, Iceland. 2 Department of Pulmonology, Skåne University Hospital, Lund, Sweden. 3 Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 4 Department of Pulmonology, Landspitali University Hospital, Reykjavik, Iceland.
Format: Article in Journal/Newspaper
Language:English
Published: AME Publishing Company 2019
Subjects:
Non-small cell lung cancer (NSCLC)
long-term survival
outcome
prognosis
pulmonary resection
Lungnakrabbamein
Skurðlækningar
Carcinoma
Non-Small-Cell Lung
Pulmonary Surgical Procedures
Lung Neoplasms
TNM
Iceland
Online Access:http://hdl.handle.net/2336/620895
https://doi.org/10.21037/atm.2019.01.10
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Summary:To access publisher's full text version of this article click on the hyperlink below We studied the outcome of pulmonary resection with curative intent for non-small cell lung cancer (NSCLC) in a nationwide study covering a 24-year period, focusing on survival. All patients who underwent pulmonary resection for NSCLC in Iceland in the period 1991-2014 were reviewed for demographics, TNM stage and survival. Median length of follow-up was 45 months. Three 8-year periods were compared, overall survival was estimated, and prognostic factors for survival were identified. Altogether, 652 surgical resections were performed on 644 individuals (52% females): 492 lobectomies (75%), 77 pneumonectomies (12%), and 83 sublobar resections (13%). Mean age increased from 65 to 68 yrs during the study period (P=0.002). The number of cases operated at stage IA increased substantially between the first and last periods (29% Survival of patients who have undergone pulmonary resection for NSCLC has improved significantly in Iceland. This may be explained by the increased number of patients diagnosed at lower stages and improved preoperative staging, with fewer understaged patients. Landspitali University Research Fund University of Iceland Research Fund

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