Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study.
To access publisher's full text version of this article click on the hyperlink below An increase in the incidence of kidney stone disease has been reported for all age groups worldwide. To examine this trend, we conducted a nationwide study of the epidemiology of kidney stones in Icelandic chil...
Published in: | Pediatric Nephrology |
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Online Access: | http://hdl.handle.net/2336/620647 https://doi.org/10.1007/s00467-018-3947-x |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620647 2023-05-15T16:52:47+02:00 Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. Edvardsson, Vidar O Ingvarsdottir, Solborg E Palsson, Runolfur Indridason, Olafur S 1 Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. vidare@landspitali.is. 2 Children's Medical Center, Landspitali-The National University Hospital of Iceland, 101, Reykjavik, Iceland. vidare@landspitali.is. 3 Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. 4 Children's Medical Center, Landspitali-The National University Hospital of Iceland, 101, Reykjavik, Iceland. 5 Division of Nephrology, Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland. 2018 http://hdl.handle.net/2336/620647 https://doi.org/10.1007/s00467-018-3947-x en eng Springer https://link.springer.com/content/pdf/10.1007%2Fs00467-018-3947-x.pdf Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. 2018, 33 (8):1375-1384 Pediatr. Nephrol. 1432-198X 29626242 doi:10.1007/s00467-018-3947-x http://hdl.handle.net/2336/620647 Pediatric nephrology (Berlin, Germany) Archived with thanks to Pediatric nephrology (Berlin, Germany) National Consortium - Landsaðgangur Nýrnasteinar Börn Unglingar Kidney Calculi Child Adolescent Nephrolithiasis Urolithiasis Article 2018 ftlandspitaliuni https://doi.org/10.1007/s00467-018-3947-x 2022-05-29T08:22:21Z To access publisher's full text version of this article click on the hyperlink below An increase in the incidence of kidney stone disease has been reported for all age groups worldwide. To examine this trend, we conducted a nationwide study of the epidemiology of kidney stones in Icelandic children and adolescents over a 30-year period. Computerized databases of all major hospitals and medical imaging centers in Iceland were searched for International Classification of Diseases and radiologic and surgical procedure codes indicative of kidney stones in patients aged < 18 years, followed by a thorough medical record review. Age-adjusted incidence was calculated for the time intervals 1985-1989, 1990-1994, 1995-1999, 2000-2004, 2005-2009, and 2010-2013. Time trends in stone incidence were assessed by Poisson regression. The prevalence of stone disease for the years 1999-2013 was also determined. Almost all the 190 patients (97%) that we identified had symptomatic stones, and acute flank or abdominal pain and hematuria were the most common presenting features. The total annual incidence of kidney stones increased from 3.7/100,000 in the first 5-year interval to 11.0/100,000 during the years 1995-2004 (p < 0.001) and decreased thereafter to 8.7/100,000 in 2010-2013 (p = 0.63). The incidence rise was highest in girls aged 13-17 years, in whom it rose from 9.8/100,000 in 1985-1989 to 39.2/100,000 in 2010-2013 (p < 0.001), resulting in an overall female predominance in this age group. The mean annual prevalence of stone disease in 1999-2013 was 48/100,000 for boys and 52/100,000 for girls. We found a significant increase in the incidence of childhood kidney stone disease, driven by a dramatic increase of stone frequency in teenage females which is poorly understood and warrants further study. Landspitali University Hospital Research Fund Rare Kidney Stone Consortium a part of the National Center for Advancing Translational Sciences' (NCATS) Rare Diseases Clinical Research Network (RDCRN), which is an ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Pediatric Nephrology 33 8 1375 1384 |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Nýrnasteinar Börn Unglingar Kidney Calculi Child Adolescent Nephrolithiasis Urolithiasis |
spellingShingle |
Nýrnasteinar Börn Unglingar Kidney Calculi Child Adolescent Nephrolithiasis Urolithiasis Edvardsson, Vidar O Ingvarsdottir, Solborg E Palsson, Runolfur Indridason, Olafur S Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
topic_facet |
Nýrnasteinar Börn Unglingar Kidney Calculi Child Adolescent Nephrolithiasis Urolithiasis |
description |
To access publisher's full text version of this article click on the hyperlink below An increase in the incidence of kidney stone disease has been reported for all age groups worldwide. To examine this trend, we conducted a nationwide study of the epidemiology of kidney stones in Icelandic children and adolescents over a 30-year period. Computerized databases of all major hospitals and medical imaging centers in Iceland were searched for International Classification of Diseases and radiologic and surgical procedure codes indicative of kidney stones in patients aged < 18 years, followed by a thorough medical record review. Age-adjusted incidence was calculated for the time intervals 1985-1989, 1990-1994, 1995-1999, 2000-2004, 2005-2009, and 2010-2013. Time trends in stone incidence were assessed by Poisson regression. The prevalence of stone disease for the years 1999-2013 was also determined. Almost all the 190 patients (97%) that we identified had symptomatic stones, and acute flank or abdominal pain and hematuria were the most common presenting features. The total annual incidence of kidney stones increased from 3.7/100,000 in the first 5-year interval to 11.0/100,000 during the years 1995-2004 (p < 0.001) and decreased thereafter to 8.7/100,000 in 2010-2013 (p = 0.63). The incidence rise was highest in girls aged 13-17 years, in whom it rose from 9.8/100,000 in 1985-1989 to 39.2/100,000 in 2010-2013 (p < 0.001), resulting in an overall female predominance in this age group. The mean annual prevalence of stone disease in 1999-2013 was 48/100,000 for boys and 52/100,000 for girls. We found a significant increase in the incidence of childhood kidney stone disease, driven by a dramatic increase of stone frequency in teenage females which is poorly understood and warrants further study. Landspitali University Hospital Research Fund Rare Kidney Stone Consortium a part of the National Center for Advancing Translational Sciences' (NCATS) Rare Diseases Clinical Research Network (RDCRN), which is an ... |
author2 |
1 Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. vidare@landspitali.is. 2 Children's Medical Center, Landspitali-The National University Hospital of Iceland, 101, Reykjavik, Iceland. vidare@landspitali.is. 3 Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. 4 Children's Medical Center, Landspitali-The National University Hospital of Iceland, 101, Reykjavik, Iceland. 5 Division of Nephrology, Internal Medicine Services, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland. |
format |
Article in Journal/Newspaper |
author |
Edvardsson, Vidar O Ingvarsdottir, Solborg E Palsson, Runolfur Indridason, Olafur S |
author_facet |
Edvardsson, Vidar O Ingvarsdottir, Solborg E Palsson, Runolfur Indridason, Olafur S |
author_sort |
Edvardsson, Vidar O |
title |
Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
title_short |
Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
title_full |
Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
title_fullStr |
Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
title_full_unstemmed |
Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
title_sort |
incidence of kidney stone disease in icelandic children and adolescents from 1985 to 2013: results of a nationwide study. |
publisher |
Springer |
publishDate |
2018 |
url |
http://hdl.handle.net/2336/620647 https://doi.org/10.1007/s00467-018-3947-x |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
https://link.springer.com/content/pdf/10.1007%2Fs00467-018-3947-x.pdf Incidence of kidney stone disease in Icelandic children and adolescents from 1985 to 2013: results of a nationwide study. 2018, 33 (8):1375-1384 Pediatr. Nephrol. 1432-198X 29626242 doi:10.1007/s00467-018-3947-x http://hdl.handle.net/2336/620647 Pediatric nephrology (Berlin, Germany) |
op_rights |
Archived with thanks to Pediatric nephrology (Berlin, Germany) National Consortium - Landsaðgangur |
op_doi |
https://doi.org/10.1007/s00467-018-3947-x |
container_title |
Pediatric Nephrology |
container_volume |
33 |
container_issue |
8 |
container_start_page |
1375 |
op_container_end_page |
1384 |
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1766043198583472128 |