Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark
To access publisher's full text version of this article click on the hyperlink below Currently, data on Escherichia coli antibacterial susceptibilities in the Faroe Islands are lacking. The aim was to investigate the antibacterial susceptibilities of E. coli from patients with community-acquire...
Published in: | Microbial Drug Resistance |
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Main Authors: | , , , |
Other Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Mary Ann Liebert
2018
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Subjects: | |
Online Access: | http://hdl.handle.net/2336/620460 https://doi.org/10.1089/mdr.2017.0034 |
_version_ | 1821508234343612416 |
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author | Magnussen, Marita Debess Gislason, Hannes Gaini, Shahin Kristinsson, Karl G. |
author2 | 1 Thetis, Food & Environm Lab, Vio Myllutjorn 6, FO-100 Torshavn, Faroe Islands, Denmark Show more 2 Univ Iceland, Med Fac, Reykjavik, Iceland 3 Univ Faroe Isl, Fac Sci & Technol, Torshavn, Faroe Islands, Denmark 4 Queen Alexandrines Teaching Hosp, Natl Hosp Faroe Isl, Dept Internal Med, Torshavn, Faroe Islands, Denmark 5 Queen Alexandrines Teaching Hosp, Natl Hosp Faroe Isl, Med Dept, Res Unit, Torshavn, Faroe Islands, Denmark Show more 6 Odense Univ Hosp, Dept Infect Dis, Odense, Denmark Show more 7 Univ Southern Denmark, Odense, Denmark Show more 8 Landspitali Univ Hosp, Dept Clin Microbiol, Reykjavik, Iceland Thetis, Food and Environmental Laboratory, Tórshavn, Faroe Islands. Faculty of Science and Technology, University of the Faroe Islands, Tórshavn, Faroe Islands. Medical Faculty, University of Iceland, Reykjavík, Iceland. |
author_facet | Magnussen, Marita Debess Gislason, Hannes Gaini, Shahin Kristinsson, Karl G. |
author_sort | Magnussen, Marita Debess |
collection | Hirsla - Landspítali University Hospital research archive |
container_issue | 1 |
container_start_page | 40 |
container_title | Microbial Drug Resistance |
container_volume | 24 |
description | To access publisher's full text version of this article click on the hyperlink below Currently, data on Escherichia coli antibacterial susceptibilities in the Faroe Islands are lacking. The aim was to investigate the antibacterial susceptibilities of E. coli from patients with community-acquired urinary tract infections in the Faroe Islands, correlate with antibacterial sales, and compare with Iceland and Denmark. From 2009 to 2010 and in 2012, 12 general practitioners from the Faroe Islands were recruited to provide urine samples from patients. Antibacterial susceptibilities were determined by disc diffusion testing according to the Clinical and Laboratory Standards Institute methods and criteria. Logistic regression (quasibinomial) of the antibacterial resistance proportions versus mean sales during the period of 2008-2011 was used to determine association. Nonsusceptibility to at least 1 of the 14 antibacterial drugs investigated was found in 54% of the E. coli isolates and was most common to ampicillin (46%), followed by sulfamethoxazole (39%), trimethoprim (27%), trimethoprim/sulfamethoxazole (27%), and <10% to the remaining 10 antibiotics. The resistance prevalence did not change significantly with time. From logistic regression modeling, we find significant associations between antibacterial mean sales and antibacterial resistances. For the resistances in the Faroe Islands compared with data from Denmark and Iceland, we infer two groups of resistances indicating different responses-one steep and one gradual-to antibacterial sales. For these two groups, we find β1 = 4.77 (Std. Error = 0.624, p-value = 0.002) and β1 = 0.26 (Std. Error = 0.020, p-value = 4e-7) for the steep and gradual groups, respectively. This knowledge can potentially be used to predict and control the future increase in E. coli resistance with antibacterial sales. Faroese research Council BP Amoco Chevron Texaco Eik Visindagrunninum SSAC foundation |
format | Article in Journal/Newspaper |
genre | Faroe Islands Iceland |
genre_facet | Faroe Islands Iceland |
geographic | Eik Faroe Islands |
geographic_facet | Eik Faroe Islands |
id | ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620460 |
institution | Open Polar |
language | English |
long_lat | ENVELOPE(6.668,6.668,62.627,62.627) |
op_collection_id | ftlandspitaliuni |
op_container_end_page | 47 |
op_doi | https://doi.org/10.1089/mdr.2017.0034 |
op_relation | http://online.liebertpub.com/doi/10.1089/mdr.2017.0034 Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark 2018, 24 (1):40 Microbial Drug Resistance 1076-6294 1931-8448 doi:10.1089/mdr.2017.0034 http://hdl.handle.net/2336/620460 Microbial Drug Resistance |
op_rights | Archived with thanks to Microbial Drug Resistance Closed - Lokað |
publishDate | 2018 |
publisher | Mary Ann Liebert |
record_format | openpolar |
spelling | ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620460 2025-01-16T21:48:57+00:00 Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark Magnussen, Marita Debess Gislason, Hannes Gaini, Shahin Kristinsson, Karl G. 1 Thetis, Food & Environm Lab, Vio Myllutjorn 6, FO-100 Torshavn, Faroe Islands, Denmark Show more 2 Univ Iceland, Med Fac, Reykjavik, Iceland 3 Univ Faroe Isl, Fac Sci & Technol, Torshavn, Faroe Islands, Denmark 4 Queen Alexandrines Teaching Hosp, Natl Hosp Faroe Isl, Dept Internal Med, Torshavn, Faroe Islands, Denmark 5 Queen Alexandrines Teaching Hosp, Natl Hosp Faroe Isl, Med Dept, Res Unit, Torshavn, Faroe Islands, Denmark Show more 6 Odense Univ Hosp, Dept Infect Dis, Odense, Denmark Show more 7 Univ Southern Denmark, Odense, Denmark Show more 8 Landspitali Univ Hosp, Dept Clin Microbiol, Reykjavik, Iceland Thetis, Food and Environmental Laboratory, Tórshavn, Faroe Islands. Faculty of Science and Technology, University of the Faroe Islands, Tórshavn, Faroe Islands. Medical Faculty, University of Iceland, Reykjavík, Iceland. 2018 http://hdl.handle.net/2336/620460 https://doi.org/10.1089/mdr.2017.0034 en eng Mary Ann Liebert http://online.liebertpub.com/doi/10.1089/mdr.2017.0034 Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark 2018, 24 (1):40 Microbial Drug Resistance 1076-6294 1931-8448 doi:10.1089/mdr.2017.0034 http://hdl.handle.net/2336/620460 Microbial Drug Resistance Archived with thanks to Microbial Drug Resistance Closed - Lokað Þvagfærasjúkdómar Gerlar Lyfhrifafræði Sýklalyf BAC12 Escherichia coli Drug Resistance Bacterial Urinary Tract Infections Article 2018 ftlandspitaliuni https://doi.org/10.1089/mdr.2017.0034 2022-05-29T08:22:19Z To access publisher's full text version of this article click on the hyperlink below Currently, data on Escherichia coli antibacterial susceptibilities in the Faroe Islands are lacking. The aim was to investigate the antibacterial susceptibilities of E. coli from patients with community-acquired urinary tract infections in the Faroe Islands, correlate with antibacterial sales, and compare with Iceland and Denmark. From 2009 to 2010 and in 2012, 12 general practitioners from the Faroe Islands were recruited to provide urine samples from patients. Antibacterial susceptibilities were determined by disc diffusion testing according to the Clinical and Laboratory Standards Institute methods and criteria. Logistic regression (quasibinomial) of the antibacterial resistance proportions versus mean sales during the period of 2008-2011 was used to determine association. Nonsusceptibility to at least 1 of the 14 antibacterial drugs investigated was found in 54% of the E. coli isolates and was most common to ampicillin (46%), followed by sulfamethoxazole (39%), trimethoprim (27%), trimethoprim/sulfamethoxazole (27%), and <10% to the remaining 10 antibiotics. The resistance prevalence did not change significantly with time. From logistic regression modeling, we find significant associations between antibacterial mean sales and antibacterial resistances. For the resistances in the Faroe Islands compared with data from Denmark and Iceland, we infer two groups of resistances indicating different responses-one steep and one gradual-to antibacterial sales. For these two groups, we find β1 = 4.77 (Std. Error = 0.624, p-value = 0.002) and β1 = 0.26 (Std. Error = 0.020, p-value = 4e-7) for the steep and gradual groups, respectively. This knowledge can potentially be used to predict and control the future increase in E. coli resistance with antibacterial sales. Faroese research Council BP Amoco Chevron Texaco Eik Visindagrunninum SSAC foundation Article in Journal/Newspaper Faroe Islands Iceland Hirsla - Landspítali University Hospital research archive Eik ENVELOPE(6.668,6.668,62.627,62.627) Faroe Islands Microbial Drug Resistance 24 1 40 47 |
spellingShingle | Þvagfærasjúkdómar Gerlar Lyfhrifafræði Sýklalyf BAC12 Escherichia coli Drug Resistance Bacterial Urinary Tract Infections Magnussen, Marita Debess Gislason, Hannes Gaini, Shahin Kristinsson, Karl G. Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark |
title | Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark |
title_full | Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark |
title_fullStr | Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark |
title_full_unstemmed | Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark |
title_short | Antibacterial Susceptibilities of Escherichia coli from Community-Acquired Urinary Tract Infections in the Faroe Islands, Associations with Antibacterial Sales, and Comparison with Iceland and Denmark |
title_sort | antibacterial susceptibilities of escherichia coli from community-acquired urinary tract infections in the faroe islands, associations with antibacterial sales, and comparison with iceland and denmark |
topic | Þvagfærasjúkdómar Gerlar Lyfhrifafræði Sýklalyf BAC12 Escherichia coli Drug Resistance Bacterial Urinary Tract Infections |
topic_facet | Þvagfærasjúkdómar Gerlar Lyfhrifafræði Sýklalyf BAC12 Escherichia coli Drug Resistance Bacterial Urinary Tract Infections |
url | http://hdl.handle.net/2336/620460 https://doi.org/10.1089/mdr.2017.0034 |