Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study
To access publisher's full text version of this article click on the hyperlink below OBJECTIVE: Limited data exist on the changes in the epidemiology of pancreatic cancer and outcomes over the last decades in population-based cohorts. We aimed to compare the incidence of pancreatic cancer, diag...
Published in: | Scandinavian Journal of Gastroenterology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Taylor & Francis
2018
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Online Access: | http://hdl.handle.net/2336/620442 https://doi.org/10.1080/00365521.2017.1390598 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620442 2023-05-15T16:48:45+02:00 Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study Jonsdottir, Sara B. Juliusson, Gunnar Kristinsson, Jon Ö. Hreinsson, Johann P. Jonasson, Jon G. Björnsson, Einar S. 1 Landspitali Univ Hosp, Div Gastroenterol & Hepatol, Dept Internal Med, Reykjavik, Iceland Show more 2 Univ Iceland, Fac Med, Reykjavik, Iceland Show more 3 Landspitali Univ Hosp, Dept Pathol, Reykjavik, Iceland 4 Krabbameinsfelagid Isl, Iceland Canc Soc, Iceland Canc Registry, Reykjavik, Iceland Department of Internal Medicine, Division of Gastroenterology and Hepatology, Landspitali University Hospital, Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland; 2018 http://hdl.handle.net/2336/620442 https://doi.org/10.1080/00365521.2017.1390598 en eng Taylor & Francis https://www.tandfonline.com/doi/full/10.1080/00365521.2017.1390598 Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study 2017, 53 (1):100 Scandinavian Journal of Gastroenterology 0036-5521 1502-7708 doi:10.1080/00365521.2017.1390598 http://hdl.handle.net/2336/620442 Scandinavian Journal of Gastroenterology Archived with thanks to Scandinavian Journal of Gastroenterology Landspitali Access - LSH-aðgangur Krabbamein Bris Lækningar Lífslíkur GAS12 Pancreatic Neoplasms Survival Therapeutics Article 2018 ftlandspitaliuni https://doi.org/10.1080/00365521.2017.1390598 2022-05-29T08:22:18Z To access publisher's full text version of this article click on the hyperlink below OBJECTIVE: Limited data exist on the changes in the epidemiology of pancreatic cancer and outcomes over the last decades in population-based cohorts. We aimed to compare the incidence of pancreatic cancer, diagnostic, treatment and survival among patients diagnosed over the period 1986-2009. MATERIALS AND METHODS: A retrospective, nationwide, population-based study. All patients diagnosed with pancreatic cancer in Iceland in two periods, 1986-1997 (P1) and 1998-2009 (P2) were identified through the Icelandic Cancer Registry and relevant clinical information obtained from medical records. RESULTS: A total of 645 patients were identified, 296 in P1 and 349 in P2 (NS). The incidence during P1 was 6.8 per 100,000 inhabitants and 6.2 during P2 (NS). Among biopsy-proven cancers, adenocarcinoma was diagnosed in 89% of the cases in P1 and in P2 in 93% of the cases. Overall 38 (14%) in P1 underwent resection and 22 (7%) in P2 (p < .0004). Patients diagnosed in P2 had longer survival at 6 months (p = .015, log-rank test) and one year (p = .0206) after diagnosis. A total of 4/296 (1.4%) in P1 survived more than 5 years and 3/349 (0.9%) in P2 (NS). CONCLUSIONS: The incidence among patients with pancreatic cancer in Iceland did not show major changes during the last 20 years. Diagnostic approach has changed considerably demonstrating more patients that are not 'resectable'. Survival rate at 6 months and one year has improved over the last two decades whereas the 5-year prognosis has not improved. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Bris ENVELOPE(-59.824,-59.824,-63.983,-63.983) Scandinavian Journal of Gastroenterology 53 1 100 106 |
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Hirsla - Landspítali University Hospital research archive |
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ftlandspitaliuni |
language |
English |
topic |
Krabbamein Bris Lækningar Lífslíkur GAS12 Pancreatic Neoplasms Survival Therapeutics |
spellingShingle |
Krabbamein Bris Lækningar Lífslíkur GAS12 Pancreatic Neoplasms Survival Therapeutics Jonsdottir, Sara B. Juliusson, Gunnar Kristinsson, Jon Ö. Hreinsson, Johann P. Jonasson, Jon G. Björnsson, Einar S. Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
topic_facet |
Krabbamein Bris Lækningar Lífslíkur GAS12 Pancreatic Neoplasms Survival Therapeutics |
description |
To access publisher's full text version of this article click on the hyperlink below OBJECTIVE: Limited data exist on the changes in the epidemiology of pancreatic cancer and outcomes over the last decades in population-based cohorts. We aimed to compare the incidence of pancreatic cancer, diagnostic, treatment and survival among patients diagnosed over the period 1986-2009. MATERIALS AND METHODS: A retrospective, nationwide, population-based study. All patients diagnosed with pancreatic cancer in Iceland in two periods, 1986-1997 (P1) and 1998-2009 (P2) were identified through the Icelandic Cancer Registry and relevant clinical information obtained from medical records. RESULTS: A total of 645 patients were identified, 296 in P1 and 349 in P2 (NS). The incidence during P1 was 6.8 per 100,000 inhabitants and 6.2 during P2 (NS). Among biopsy-proven cancers, adenocarcinoma was diagnosed in 89% of the cases in P1 and in P2 in 93% of the cases. Overall 38 (14%) in P1 underwent resection and 22 (7%) in P2 (p < .0004). Patients diagnosed in P2 had longer survival at 6 months (p = .015, log-rank test) and one year (p = .0206) after diagnosis. A total of 4/296 (1.4%) in P1 survived more than 5 years and 3/349 (0.9%) in P2 (NS). CONCLUSIONS: The incidence among patients with pancreatic cancer in Iceland did not show major changes during the last 20 years. Diagnostic approach has changed considerably demonstrating more patients that are not 'resectable'. Survival rate at 6 months and one year has improved over the last two decades whereas the 5-year prognosis has not improved. |
author2 |
1 Landspitali Univ Hosp, Div Gastroenterol & Hepatol, Dept Internal Med, Reykjavik, Iceland Show more 2 Univ Iceland, Fac Med, Reykjavik, Iceland Show more 3 Landspitali Univ Hosp, Dept Pathol, Reykjavik, Iceland 4 Krabbameinsfelagid Isl, Iceland Canc Soc, Iceland Canc Registry, Reykjavik, Iceland Department of Internal Medicine, Division of Gastroenterology and Hepatology, Landspitali University Hospital, Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland; |
format |
Article in Journal/Newspaper |
author |
Jonsdottir, Sara B. Juliusson, Gunnar Kristinsson, Jon Ö. Hreinsson, Johann P. Jonasson, Jon G. Björnsson, Einar S. |
author_facet |
Jonsdottir, Sara B. Juliusson, Gunnar Kristinsson, Jon Ö. Hreinsson, Johann P. Jonasson, Jon G. Björnsson, Einar S. |
author_sort |
Jonsdottir, Sara B. |
title |
Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
title_short |
Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
title_full |
Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
title_fullStr |
Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
title_full_unstemmed |
Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
title_sort |
incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study |
publisher |
Taylor & Francis |
publishDate |
2018 |
url |
http://hdl.handle.net/2336/620442 https://doi.org/10.1080/00365521.2017.1390598 |
long_lat |
ENVELOPE(-59.824,-59.824,-63.983,-63.983) |
geographic |
Bris |
geographic_facet |
Bris |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
https://www.tandfonline.com/doi/full/10.1080/00365521.2017.1390598 Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986–2009: a population-based study 2017, 53 (1):100 Scandinavian Journal of Gastroenterology 0036-5521 1502-7708 doi:10.1080/00365521.2017.1390598 http://hdl.handle.net/2336/620442 Scandinavian Journal of Gastroenterology |
op_rights |
Archived with thanks to Scandinavian Journal of Gastroenterology Landspitali Access - LSH-aðgangur |
op_doi |
https://doi.org/10.1080/00365521.2017.1390598 |
container_title |
Scandinavian Journal of Gastroenterology |
container_volume |
53 |
container_issue |
1 |
container_start_page |
100 |
op_container_end_page |
106 |
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1766038834378702848 |